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Origins of Enzyme Catalysis: Experimental Findings for C-H Activation, New Models, and Their Relevance to Prevailing Theoretical Constructs.

• Authors : Klinman JP; Department of Chemistry, University of California , Berkeley, California 94720, United States.; Department of Molecular and Cell Biology, University of California , Berkeley, California 94720, United States.

Subjects: Biocatalysis*; Alcohol Dehydrogenase/Alcohol Dehydrogenase/Alcohol Dehydrogenase/*metabolism ; Lipoxygenases/Lipoxygenases/Lipoxygenases/*metabolism

• Source: Journal of the American Chemical Society [J Am Chem Soc] 2017 Dec 27; Vol. 139 (51), pp. 18409-18427. Date of Electronic Publication: 2017 Dec 15.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Direct ESR detection of pentadienyl radicals and peroxyl radicals in lipid peroxidation: mechanistic insight into regioselective oxygenation in lipoxygenases.

• Authors : Kitaguchi H; Department of Material and Life Science, Graduate School of Engineering, Osaka University, SORST, Japan Science and Technology Agency (JST), Suita, Osaka 565-0871, Japan.; Ohkubo K

Subjects: Alkadienes/Alkadienes/Alkadienes/*chemistry ; Lipoxygenase/Lipoxygenase/Lipoxygenase/*chemistry ; Lipoxygenase/Lipoxygenase/Lipoxygenase/*metabolism

• Source: Journal of the American Chemical Society [J Am Chem Soc] 2005 May 11; Vol. 127 (18), pp. 6605-9.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print Cited Medium: Print ISSN:

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Interaction between non-heme iron of lipoxygenases and cumene hydroperoxide: basis for enzyme activation, inactivation, and inhibition.

• Authors : Vahedi-Faridi A; Department of Chemistry, University of Toledo, 2801 West Bancroft Street, Toledo, Ohio 43606, USA.; Brault PA

Subjects: Benzene Derivatives/Benzene Derivatives/Benzene Derivatives/*pharmacology ; Lipoxygenase/Lipoxygenase/Lipoxygenase/*metabolism ; Lipoxygenase Inhibitors/Lipoxygenase Inhibitors/Lipoxygenase Inhibitors/*pharmacology

• Source: Journal of the American Chemical Society [J Am Chem Soc] 2004 Feb 25; Vol. 126 (7), pp. 2006-15.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print Cited Medium: Print ISSN:

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Applied Science & Technology Full Text (H.W. Wilson)

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Applied Science & Technology Full Text (H.W. Wilson)

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Applied Science & Technology Full Text (H.W. Wilson)

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Extremely Elevated Room-Temperature Kinetic Isotope Effects Quantify the Critical Role of Barrier Width in Enzymatic C-H Activation.

• Authors : Shenshen Hu^1,2; Sharma, Sudhir C.^1,2; Scouras, Alexander D.^2,3

Subjects: *LIPOXYGENASES; *KINETIC isotope effects; *ENZYMATIC analysis

• Source: Journal of the American Chemical Society. 6/11/2014, Vol. 136 Issue 23, p8157-8160. 4p.

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Applied Science & Technology Full Text (H.W. Wilson)

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Applied Science & Technology Full Text (H.W. Wilson)

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Applied Science & Technology Full Text (H.W. Wilson)

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