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Academic Journal

Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson's disease.

  • Authors : Marinova-Mutafchieva L; Parkinson's Disease Research Group, Department of Cellular and Molecular Neuroscience, Division of Neuroscience and Mental Health, Faculty of Medicine, Imperial College London, London, UK.; Sadeghian M

Subjects: Disease Models, Animal* ; Oxidopamine*; Dopamine/Dopamine/Dopamine/*physiology

  • Source: Journal of neurochemistry [J Neurochem] 2009 Aug; Vol. 110 (3), pp. 966-75. Date of Electronic Publication: 2009 Jun 22.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic

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Academic Journal

Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death.

  • Authors : Monti B; Department of Biology, University of Bologna, Bologna, Italy.; Polazzi E

Subjects: Neuroprotective Agents*; Cerebellum/Cerebellum/Cerebellum/*cytology ; Cerebellum/Cerebellum/Cerebellum/*drug effects

  • Source: Journal of neurochemistry [J Neurochem] 2007 Oct; Vol. 103 (2), pp. 518-30. Date of Electronic Publication: 2007 Jul 17.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic

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Academic Journal

Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease.

  • Authors : Soto-Otero R; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Santiago de Compostela, Spain. ; Méndez-Alvarez E

Subjects: Antioxidants/Antioxidants/Antioxidants/*pharmacology ; Ascorbic Acid/Ascorbic Acid/Ascorbic Acid/*pharmacology ; Oxidopamine/Oxidopamine/Oxidopamine/*toxicity

  • Source: Journal of neurochemistry [J Neurochem] 2000 Apr; Vol. 74 (4), pp. 1605-12.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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Academic Journal

Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF.

  • Authors : Cohen AD; Department of Neurology and Center for Neuroscience, University of Pittsburgh, Philadelphia, USA.; Tillerson JL

Subjects: Forelimb*/Forelimb*/Forelimb*/physiopathology; Medial Forebrain Bundle/Medial Forebrain Bundle/Medial Forebrain Bundle/*drug effects ; Nerve Growth Factors/Nerve Growth Factors/Nerve Growth Factors/*metabolism

  • Source: Journal of neurochemistry [J Neurochem] 2003 Apr; Vol. 85 (2), pp. 299-305.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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Academic Journal

Chromaffin cell death induced by 6-hydroxydopamine is independent of mitochondrial swelling and caspase activation.

  • Authors : Galindo MF; Centro Regional de Investigaciones Biomédicas y Dpto. de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, Avda. España, s/n, 02071 Albacete, Spain.; Jordán J

Subjects: Caspases/Caspases/Caspases/*metabolism ; Chromaffin Cells/Chromaffin Cells/Chromaffin Cells/*drug effects ; Chromaffin Cells/Chromaffin Cells/Chromaffin Cells/*enzymology

  • Source: Journal of neurochemistry [J Neurochem] 2003 Mar; Vol. 84 (5), pp. 1066-73.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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Academic Journal

6-hydroxydopamine increases the hydroxylation and nitration of phenylalanine in vivo: implication of peroxynitrite formation.

  • Authors : Ferger B; Wolfson Centre for Age-Related Diseases, Guy's, King's & St Thomas' School of Biomedical Sciences, King's College London, London, UK. ; Themann C

Subjects: Corpus Striatum/Corpus Striatum/Corpus Striatum/*metabolism ; Nitrates/Nitrates/Nitrates/*metabolism ; Oxidopamine/Oxidopamine/Oxidopamine/*pharmacology

  • Source: Journal of neurochemistry [J Neurochem] 2001 Aug; Vol. 78 (3), pp. 509-14.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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Academic Journal

Copper increases the ability of 6-hydroxydopamine to generate oxidative stress and the ability of ascorbate and glutathione to potentiate this effect: potential implications in Parkinson's disease.

  • Authors : Cruces-Sande A; Laboratory of Neurochemistry, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain.; Méndez-Álvarez E

Subjects: Adrenergic Agents/Adrenergic Agents/Adrenergic Agents/*pharmacology ; Antioxidants/Antioxidants/Antioxidants/*pharmacology ; Ascorbic Acid/Ascorbic Acid/Ascorbic Acid/*pharmacology

  • Source: Journal of neurochemistry [J Neurochem] 2017 Jun; Vol. 141 (5), pp. 738-749. Date of Electronic Publication: 2017 Apr 06.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic

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Academic Journal

Absence of 6-hydroxydopamine in the rat brain after treatment with stimulants and other dopaminergic agents: a mass fragmentographic study.

  • Authors : Karoum F; Neuropsychiatry Branch, Intramural Research Program, National Institute of Mental Health, Neuroscience Research Center, Washington, D.C. 20032.; Chrapusta SJ

Subjects: Brain/Brain/Brain/*metabolism ; Dopamine Agents/Dopamine Agents/Dopamine Agents/*pharmacology ; Oxidopamine/Oxidopamine/Oxidopamine/*metabolism

  • Source: Journal of neurochemistry [J Neurochem] 1993 Oct; Vol. 61 (4), pp. 1369-75.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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Academic Journal

Neonatal 6-hydroxydopamine and adult SKF 38393 treatments alter dopamine D1 receptor mRNA levels: absence of other neurochemical associations with the enhanced behavioral responses of lesioned rats.

  • Authors : Gong L; Department of Pharmacology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614.; Kostrzewa RM

Subjects: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/*pharmacology ; Aging/Aging/Aging/*metabolism ; Brain/Brain/Brain/*metabolism

  • Source: Journal of neurochemistry [J Neurochem] 1994 Oct; Vol. 63 (4), pp. 1282-90.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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Academic Journal

Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system.

  • Authors : Spina MB; Regeneron Pharmaceuticals, Inc., Tarrytown, New York 10591.; Squinto SP

Subjects: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/*pharmacology ; Dopamine/Dopamine/Dopamine/*metabolism ; Glutathione/Glutathione/Glutathione/*physiology

  • Source: Journal of neurochemistry [J Neurochem] 1992 Jul; Vol. 59 (1), pp. 99-106.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

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