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Diester Prodrugs of a Phosphonate Butyrophilin Ligand Display Improved Cell Potency, Plasma Stability, and Payload Internalization.

• Authors : Singh, Umed; Pawge, Girija; Rani, Sarita

• Source: Journal of Medicinal Chemistry; 11/23/2023, Vol. 66 Issue 22, p15309-15325, 17p

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Development of N‑Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability.

• Authors : Harms, Mirja; Fabech Hansson, Rikke; Gilg, Andrea

• Source: Journal of Medicinal Chemistry; 11/23/2023, Vol. 66 Issue 22, p15189-15204, 16p

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Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent Vγ9 Vδ2 T Cell Stimulation.

• Authors : Lentini, Nicholas A.; Foust, Benjamin J.; Hsiao, Chia-Hung Christine

• Source: Journal of Medicinal Chemistry; 10/11/2018, Vol. 61 Issue 19, p8658-8669, 12p

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Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox.

• Authors : Hermant, Paul; Bosc, Damien; Piveteau, Catherine

• Source: Journal of Medicinal Chemistry; 11/9/2017, Vol. 60 Issue 21, p9067-9089, 23p

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Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox

• Authors : Hermant, Paul; Bosc, Damien; Piveteau, Catherine

• Source: Journal of Medicinal Chemistry; 20240101, Issue: Preprints

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Modulating Oxytocin Activity and Plasma Stability by Disulfide Bond Engineering.

• Authors : Muttenthaler, Markus; Andersson, Asa; de Araujo, Aline D.

• Source: Journal of Medicinal Chemistry; 12/23/2010, Vol. 53 Issue 24, p8585-8596, 12p

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Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity.

• Authors : Les P. Miranda; Katherine A. Winters; Colin V. Gegg

• Source: Journal of Medicinal Chemistry; Apr2008, Vol. 51 Issue 9, p2758-2765, 8p

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Hydroxamates: relationships between structure and plasma stability.

• Authors : Flipo M; INSERM U761 Biostructures and Drug Discovery, Univ Lille Nord de France, Lille F-59006, France.; Charton J

Subjects: Hydroxamic Acids/Hydroxamic Acids/Hydroxamic Acids/*chemical synthesis; Animals ; Drug Evaluation, Preclinical

• Source: Journal of medicinal chemistry [J Med Chem] 2009 Nov 12; Vol. 52 (21), pp. 6790-802.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Internet ISSN:

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Design and Synthesis of Pyrrolidine-5,5‘-trans-Lactams (5-Oxo-hexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 4. Antiviral Activity and Plasma Stability

• Authors : Borthwick, A. D.; Davies, D. E.; Ertl, P. F.

• Source: Journal of Medicinal Chemistry; October 2003, Vol. 46 Issue: 21 p4428-4449, 22p

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Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity.

• Authors : Miranda LP; Chemistry Research and Discovery, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, California 91320, USA. ; Winters KA

Subjects: Glucagon-Like Peptide 1/Glucagon-Like Peptide 1/Glucagon-Like Peptide 1/*analogs & derivatives ; Glucagon-Like Peptide 1/Glucagon-Like Peptide 1/Glucagon-Like Peptide 1/*chemical synthesis ; Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*chemical synthesis

• Source: Journal of medicinal chemistry [J Med Chem] 2008 May 08; Vol. 51 (9), pp. 2758-65. Date of Electronic Publication: 2008 Apr 15.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Print

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