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Amphiphilic Modulation of Glycosylated Antitumor Ether Lipids Results in a Potent Triamino Scaffold against Epithelial Cancer Cell Lines and BT474 Cancer Stem Cells.

• Authors : Idowu, Temilolu; Samadder, Pranati; Arthur, Gilbert

• Source: Journal of Medicinal Chemistry; 12/14/2017, Vol. 60 Issue 23, p9724-9738, 15p

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Replacing d-Glucosamine with Its l-Enantiomer in Glycosylated Antitumor Ether Lipids (GAELs) Retains Cytotoxic Effects against Epithelial Cancer Cells and Cancer Stem Cells.

• Authors : Ogunsina, Makanjuola; Samadder, Pranati; Idowu, Temilolu

• Source: Journal of Medicinal Chemistry; 3/9/2017, Vol. 60 Issue 5, p2142-2147, 6p

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Amphiphilic Modulation of Glycosylated Antitumor Ether Lipids Results in a Potent Triamino Scaffold against Epithelial Cancer Cell Lines and BT474 Cancer Stem Cells

• Authors : Idowu, Temilolu; Samadder, Pranati; Arthur, Gilbert

• Source: Journal of Medicinal Chemistry; 20240101, Issue: Preprints

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Synthesis and biological activity of anticancer ether lipids that are specifically released by phospholipase A2 in tumor tissue.

• Authors : Andresen TL; Department of Chemistry, Technical University of Denmark, Building 207, DK-2800 Lyngby, Denmark. ; Jensen SS

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Ethers/Ethers/Ethers/*chemical synthesis ; Lipids/Lipids/Lipids/*chemical synthesis

• Source: Journal of medicinal chemistry [J Med Chem] 2005 Nov 17; Vol. 48 (23), pp. 7305-14.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN:

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Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs.

• Authors : Andresen TL; Department of Chemistry and LiPlasome Pharma A/S, Technical University of Denmark, Building 207, DK-2800 Lyngby, Denmark. ; Davidsen J

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Ethers/Ethers/Ethers/*chemical synthesis ; Phospholipases A/Phospholipases A/Phospholipases A/*chemistry

• Source: Journal of medicinal chemistry [J Med Chem] 2004 Mar 25; Vol. 47 (7), pp. 1694-703.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN:

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Nucleoside conjugates. 14. Synthesis and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of ether lipids with improved water solubility.

• Authors : Hong CI; Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.; Nechaev A

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Cytarabine/Cytarabine/Cytarabine/*analogs & derivatives ; Lipids/Lipids/Lipids/*chemistry

• Source: Journal of medicinal chemistry [J Med Chem] 1995 May 12; Vol. 38 (10), pp. 1629-34.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN:

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Synthesis of alkyl chain-modified ether lipids and evaluation of their in vitro cytotoxicity.

• Authors : Fos E; Research and Development, Laboratorios Menarini SA, Badalona, Spain.; Suesa N

Subjects: Lysophospholipids/Lysophospholipids/Lysophospholipids/*chemical synthesis; Animals ; Cell Division/Cell Division/Cell Division/drug effects

• Source: Journal of medicinal chemistry [J Med Chem] 1995 Mar 31; Vol. 38 (7), pp. 1216-28.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN:

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Syntheses of racemic and nearly optically pure ether lipids and evaluation of in vitro antineoplastic activities.

• Authors : Duclos RI Jr; School of Pharmacy, University of Connecticut, Storrs 06269-2092.; Chia HH

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Phospholipid Ethers/Phospholipid Ethers/Phospholipid Ethers/*chemical synthesis; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/pharmacology

• Source: Journal of medicinal chemistry [J Med Chem] 1994 Nov 25; Vol. 37 (24), pp. 4147-54.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN:

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Synthesis of phosphocholine and quaternary amine ether lipids and evaluation of in vitro antineoplastic activity.

• Authors : Morris-Natschke SL; School of Pharmacy, Division of Medicinal Chemistry and Natural Products, University of North Carolina, Chapel Hill 27599.; Gumus F

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Lipids/Lipids/Lipids/*chemical synthesis ; Phosphorylcholine/Phosphorylcholine/Phosphorylcholine/*analogs & derivatives

• Source: Journal of medicinal chemistry [J Med Chem] 1993 Jul 09; Vol. 36 (14), pp. 2018-25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN:

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Synthesis of quaternary amine ether lipids and evaluation of neoplastic cell growth inhibitory properties.

• Authors : Morris-Natschke SL; University of North Carolina, School of Pharmacy, Division of Medicinal Chemistry and Natural Products, Chapel Hill 27599.; Meyer KL

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Ethers/Ethers/Ethers/*pharmacology ; Lipids/Lipids/Lipids/*pharmacology

• Source: Journal of medicinal chemistry [J Med Chem] 1990 Jun; Vol. 33 (6), pp. 1812-8.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN:

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