Search Results

Loss of STAT2 may be dangerous in a world filled with viruses.

• Authors : Jordan, Michael B.¹

Subjects: *STAT proteins; *VIRUS diseases; *VIRAL replication

• Source: Journal of Clinical Investigation. 6/15/2023, Vol. 133 Issue 12, p1-2. 2p.

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Reduced thymic IL-4 impairs negative T cell selection in nonobese diabetic mice.

• Authors : Cattin-Roy, Alexis N.¹; Laffey, Kimberly G.¹; Le, Luan B.¹

Subjects: *T cells; *STAT proteins; *T cell receptors

• Source: Journal of Clinical Investigation. 12/2/2024, Vol. 134 Issue 23, p1-13. 13p.

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Rare mutations provide unique insight into oncogenic potential of STAT transcription factors.

• Authors : Heppler, Lisa N.^1,2; Frank, David A.^1,2

Subjects: *GENETIC mutation; *STAT proteins; *TRANSCRIPTION factors

• Source: Journal of Clinical Investigation. Jan2018, Vol. 128 Issue 1, p113-115. 3p. 1 Color Photograph.

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Intrinsic RIG-I restrains STAT5 activation to modulate antitumor activity of CD8+ T cells.

• Authors : Xinyi Jiang¹; Jian Lin^1,2; Chengfang Shangguan³

Subjects: *T cells; *STAT proteins; *ANTINEOPLASTIC agents

• Source: Journal of Clinical Investigation. 5/1/2023, Vol. 134 Issue 9, p1-16. 17p.

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Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.

• Authors : Suske, Tobias; Sorger, Helena; Manhart, Gabriele

Subjects: T cells; LYMPHOBLASTIC leukemia; STAT proteins

• Source: Journal of Clinical Investigation. 4/15/2024, Vol. 134 Issue 8, p1-16. 16p.

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Human inherited complete STAT2 deficiency underlies inflammatory viral diseases.

• Authors : Bucciol, Giorgia; Moens, Leen; Masato Ogishi

Subjects: VIRAL encephalitis; VIRUS diseases; STAT proteins

• Source: Journal of Clinical Investigation. 6/15/2023, Vol. 133 Issue 12, p1-18. 18p.

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UBC9 deficiency enhances immunostimulatory macrophage activation and subsequent antitumor T cell response in prostate cancer.

• Authors : Jun Xiao; Ya-Nan Wang; Bo Liu

Subjects: MACROPHAGE activation; T cells; PROSTATE cancer

• Source: Journal of Clinical Investigation. 2/15/2023, Vol. 133 Issue 4, p1-16. 16p.

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STAT5BN642H is a driver mutation for T cell neoplasia.

• Authors : Ha Thi Thanh Pham^1,2; Maurer, Barbara^1,2; Prchal-Murphy, Michaela³

Subjects: *T cells; *STAT proteins; *GENETIC mutation

• Source: Journal of Clinical Investigation. Jan2018, Vol. 128 Issue 1, p387-401. 15p. 1 Color Photograph, 8 Graphs.

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IL-9/STAT3/fatty acid oxidation-mediated lipid peroxidation contributes to Tc9 cell longevity and enhanced antitumor activity

• Authors : Xiao, Liuling; Ma, Xingzhe; Ye, Lingqun

• Source: Journal of Clinical Investigation. April 1, 2022, Vol. 132 Issue 7

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Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal

• Authors : Zhou, Bing; Damrauer, Jeffrey S.; Bailey, Sean T.

• Source: Journal of Clinical Investigation. February 1, 2014, Vol. 124 Issue 2, p553, 11 p.

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