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Academic Journal

MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution.

  • Authors : Fortier SM; Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Walker NM

Subjects: Dual Specificity Phosphatase 1*/Dual Specificity Phosphatase 1*/Dual Specificity Phosphatase 1*/metabolism ; Dual Specificity Phosphatase 1*/Dual Specificity Phosphatase 1*/Dual Specificity Phosphatase 1*/genetics ; Myofibroblasts*/Myofibroblasts*/Myofibroblasts*/pathology

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Mar 21; Vol. 134 (10). Date of Electronic Publication: 2024 Mar 21.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium:

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Academic Journal

Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis.

  • Authors : Trinh-Minh T; Department of Rheumatology and.; Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, North-Rhine-Westphalia, Germany.

Subjects: Fibroblasts*/Fibroblasts*/Fibroblasts*/drug effects ; Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism ; Fibroblasts*/Fibroblasts*/Fibroblasts*/pathology

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Mar 26; Vol. 134 (10). Date of Electronic Publication: 2024 Mar 26.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium:

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Academic Journal

Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis.

  • Authors : Pachera E; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.; Assassi S

Subjects: Extracellular Matrix/Extracellular Matrix/Extracellular Matrix/*metabolism ; Myofibroblasts/Myofibroblasts/Myofibroblasts/*metabolism ; Pulmonary Fibrosis/Pulmonary Fibrosis/Pulmonary Fibrosis/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2020 Sep 01; Vol. 130 (9), pp. 4888-4905.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium:

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Academic Journal

Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface.

  • Authors : Li R; Department of Pediatrics, School of Medicine, UCSD, La Jolla, California, USA.; Li X

Subjects: Blood-Air Barrier/Blood-Air Barrier/Blood-Air Barrier/*metabolism ; Bronchopulmonary Dysplasia/Bronchopulmonary Dysplasia/Bronchopulmonary Dysplasia/*metabolism ; Myofibroblasts/Myofibroblasts/Myofibroblasts/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2020 Jun 01; Vol. 130 (6), pp. 2859-2871.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium:

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Academic Journal

TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis.

  • Authors : Dees C; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Pötter S

Subjects: Epigenesis, Genetic* ; Signal Transduction*; Myofibroblasts/Myofibroblasts/Myofibroblasts/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2020 May 01; Vol. 130 (5), pp. 2347-2363.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium:

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Academic Journal

Fra-2-expressing macrophages promote lung fibrosis in mice.

  • Authors : Ucero AC; Genes, Development and Disease Group, Cancer Cell Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Bakiri L

Subjects: Fos-Related Antigen-2/Fos-Related Antigen-2/Fos-Related Antigen-2/*biosynthesis ; Idiopathic Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis/*metabolism ; Macrophages/Macrophages/Macrophages/*immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2019 May 28; Vol. 129 (8), pp. 3293-3309. Date of Electronic Publication: 2019 May 28.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium:

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Academic Journal

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis.

  • Authors : Zhou Y; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-0006, USA. ; Huang X

Subjects: Mechanotransduction, Cellular*; Myofibroblasts/Myofibroblasts/Myofibroblasts/*physiology ; Pulmonary Fibrosis/Pulmonary Fibrosis/Pulmonary Fibrosis/*pathology

  • Source: The Journal of clinical investigation [J Clin Invest] 2013 Mar; Vol. 123 (3), pp. 1096-108. Date of Electronic Publication: 2013 Feb 22.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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Academic Journal

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart.

  • Authors : Fu X; Cincinnati Children's Hospital Medical Center (CCHMC), Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, USA.; AgCenter, School of Animal Sciences, Louisiana State University, Baton Rouge, Louisiana, USA.

Subjects: Cell Differentiation*; Cicatrix/Cicatrix/Cicatrix/*metabolism ; Extracellular Matrix/Extracellular Matrix/Extracellular Matrix/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2018 May 01; Vol. 128 (5), pp. 2127-2143. Date of Electronic Publication: 2018 Apr 16.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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Academic Journal

Endoplasmic reticulum stress in the pathogenesis of fibrotic disease.

  • Authors : Kropski JA; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Veterans Affairs Medical Center, Nashville, Tennessee, USA.

Subjects: Apoptosis* ; Endoplasmic Reticulum Stress* ; Signal Transduction*

  • Source: The Journal of clinical investigation [J Clin Invest] 2018 Jan 02; Vol. 128 (1), pp. 64-73. Date of Electronic Publication: 2018 Jan 02.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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Academic Journal

Resolution of organ fibrosis.

Subjects: Apoptosis* ; Cell Dedifferentiation* ; Cellular Reprogramming*

  • Source: The Journal of clinical investigation [J Clin Invest] 2018 Jan 02; Vol. 128 (1), pp. 97-107. Date of Electronic Publication: 2018 Jan 02.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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