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Palmitoylation acts as a checkpoint for MAVS aggregation to promote antiviral innate immune responses.

• Authors : Wang L; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, Innovation Center of the Sixth Affiliated Hospital, School of Life Sciences of Sun Yat-sen University, Guangzhou, Guangdong, China.; Li M

Subjects: Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/metabolism ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/genetics ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/immunology

• Source: The Journal of clinical investigation [J Clin Invest] 2024 Dec 02; Vol. 134 (23). Date of Electronic Publication: 2024 Dec 02.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium:

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RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.

• Authors : Ren JG; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine, Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, China.; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Subjects: Lipoylation* ; Leukemia, Myeloid*; Humans

• Source: The Journal of clinical investigation [J Clin Invest] 2023 Jun 15; Vol. 133 (12). Date of Electronic Publication: 2023 Jun 15.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium:

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Mechanisms for regulation of RAS palmitoylation and plasma membrane trafficking in hematopoietic malignancies.

• Authors : Fang Yu^1,2; Zhijian Qian^1,2

Subjects: *CELL membranes; *PALMITOYLATION; *HEMATOLOGIC malignancies

• Source: Journal of Clinical Investigation. 6/15/2023, Vol. 133 Issue 12, p1-3. 3p.

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Palmitoylation acts as a checkpoint for MAVS aggregation to promote antiviral innate immune responses.

• Authors : Liqiu Wang¹; Mengqiu Li¹; Guangyu Lian¹

Subjects: *RNA virus infections; *PALMITOYLATION; *TYPE I interferons

• Source: Journal of Clinical Investigation. 12/2/2024, Vol. 134 Issue 23, p1-18. 18p.

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Mechanisms for regulation of RAS palmitoylation and plasma membrane trafficking in hematopoietic malignancies.

• Authors : Yu F; Department of Medicine, UF Health Cancer Center, and.; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA.

Subjects: Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/genetics ; Leukemia*; Humans

• Source: The Journal of clinical investigation [J Clin Invest] 2023 Jun 15; Vol. 133 (12). Date of Electronic Publication: 2023 Jun 15.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium:

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M-current preservation contributes to anticonvulsant effects of valproic acid.

• Authors : Kay HY; Greene DL; Kang S

Subjects: Anticonvulsants/Anticonvulsants/Anticonvulsants/*pharmacology ; KCNQ2 Potassium Channel/KCNQ2 Potassium Channel/KCNQ2 Potassium Channel/*physiology ; Valproic Acid/Valproic Acid/Valproic Acid/*pharmacology

• Source: The Journal of clinical investigation [J Clin Invest] 2015 Oct 01; Vol. 125 (10), pp. 3904-14. Date of Electronic Publication: 2015 Sep 08.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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CIAO1 loss of function causes a neuromuscular disorder with compromise of nucleocytoplasmic Fe-S enzymes

• Authors : Maio, Nunziata; Orbach, Rotem; Zaharieva, Irina T.

• Source: Journal of Clinical Investigation. June 15, 2024, Vol. 134 Issue 12

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Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia.

• Authors : Crispin, Andrew; Guo, Chaoshe; Chen, Caiyong

• Source: Journal of Clinical Investigation. October, 2020, Vol. 130 Issue 10, p5245, 12 p.

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Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue.

• Authors : Song, Anying; Dai, Wenting; Jang, Min Jee

• Source: Journal of Clinical Investigation. January, 2020, Vol. 130 Issue 1, p247, 11 p.

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Cellular heterogeneity in brown adipose tissue.

• Authors : Oguri, Yasuo; Kajimura, Shingo

• Source: Journal of Clinical Investigation. January, 2020, Vol. 130 Issue 1, p65, 3 p.

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