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Innate immune cell activation by adjuvant AS01 in human lymph node explants is age independent

• Authors : Stylianou, Vicki V.; Bertram, Kirstie M.; Vo, Van Anh

• Source: Journal of Clinical Investigation. November 15, 2024, Vol. 134 Issue 22

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Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects.

• Authors : Zitvogel, Laurence^1,2,3,4; Kroemer, Guido^3,4,5

Subjects: *IMMUNOLOGICAL adjuvants; *CANCER treatment; *DRUG therapy

• Source: Journal of Clinical Investigation. Aug2009, Vol. 119 Issue 8, p2127-2130. 4p. 2 Diagrams.

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Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity.

• Authors : Stüve, Olaf^1,2,3; Youssef, Sawsan⁴; Weber, Martin S.¹

Subjects: *IMMUNOLOGICAL adjuvants; *CENTRAL nervous system; *AUTOIMMUNITY

• Source: Journal of Clinical Investigation. Apr2006, Vol. 116 Issue 4, p1037-1044. 8p. 1 Chart, 6 Graphs.

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Prevalent expression of the immunostimulatory MHC class I chain--related molecule is counteracted by shedding in prostate cancer.

• Authors : Wu, Jennifer D.¹ ; Higgins, Lily M.¹; Steinle, Alexander²

Subjects: *IMMUNOLOGICAL adjuvants; *IMMUNOMODULATORS; *PROSTATE cancer

• Source: Journal of Clinical Investigation. Aug2004, Vol. 114 Issue 4, p560-568. 9p. 1 Color Photograph, 3 Charts, 6 Graphs.

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Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

• Authors : Hanson, Melissa C.^1,2; Crespo, Monica P.²; Abraham, Wuhbet²

Subjects: *IMMUNOLOGICAL adjuvants; *DINUCLEOTIDES; *LYMPH nodes

• Source: Journal of Clinical Investigation. Jun2015, Vol. 125 Issue 6, p2532-2546. 15p.

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A therapeutic cancer vaccine delivers antigens and adjuvants to lymphoid tissues using genetically modified T cells

• Authors : Veatch, Joshua R.; Singhi, Naina; Srivastava, Shivani

• Source: Journal of Clinical Investigation. August 15, 2021, Vol. 131 Issue 16

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Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool.

• Authors : Melchionda, Frala^1,2; Fry, Terry J.¹; Milliron, Matthew J.¹

Subjects: *IMMUNOLOGICAL adjuvants; *INTERLEUKINS; *T cells

• Source: Journal of Clinical Investigation. May2005, Vol. 115 Issue 5, p1177-1187. 11p. 7 Graphs.

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Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.

• Authors : Ogongo, Paul; Steyn, Adrie J. C.; Karim, Farina

Subjects: T cells; T cell receptors; LUNGS

• Source: Journal of Clinical Investigation. Jan2020, Vol. 130 Issue 1, p214-230. 17p.

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Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire.

• Authors : Khosravi-Maharlooei, Mohsen; Obradovic, Aleksandar; Misra, Aditya

Subjects: T cell receptors; HEMATOPOIETIC stem cells; HUMAN stem cells

• Source: Journal of Clinical Investigation. Jun2019, Vol. 129 Issue 6, p2446-2462. 17p.

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Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors.

• Authors : Fangjun Chen; Zhengyun Zou; Juan Du

Subjects: IMMUNOTHERAPY; T cells; DENDRITIC cells

• Source: Journal of Clinical Investigation. May2019, Vol. 129 Issue 5, p2056-2070. 15p.

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