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Publication : journal of clinical investigation

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Academic Journal

Transcript splicing optimizes the thymic self-antigen repertoire to suppress autoimmunity.

Authors : Ryunosuke Muro^1,2; Takeshi Nitta^1,2; Sachiko Nitta¹

Subjects: *IMMUNOLOGICAL tolerance; *GENETIC transcription regulation; *EPITHELIAL cells

Source: Journal of Clinical Investigation. 10/15/2024, Vol. 134 Issue 20, p1-14. 14p.

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Academic Journal

The mechanosensory channel PIEZO1 functions upstream of angiopoietin/TIE/FOXO1 signaling in lymphatic development.

Authors : Jing Du¹; Pan Liu¹; Yalu Zhou¹

Subjects: *GENETIC transcription regulation; *PROTEIN-tyrosine kinases; *GENETIC regulation

Source: Journal of Clinical Investigation. 5/15/2024, Vol. 134 Issue 10, p1-15. 15p.

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Academic Journal

mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b.

Authors : Uehara, Kahealani^1,2,3; Won Dong Lee^4,5,6; Stefkovich, Megan¹

Subjects: *GLYCOGEN; *GENETIC transcription regulation; *MICE genetics

Source: Journal of Clinical Investigation. 4/1/2024, Vol. 134 Issue 7, p1-12. 12p.

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Academic Journal

RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3.

Authors : Wei Han¹ (AUTHOR); Zhongshuai Xin^1,2 (AUTHOR); Zhiqiang Zhao¹ (AUTHOR)

Subjects: *CARRIER proteins; *GENETIC transcription regulation; *GLIOMAS

Source: Journal of Clinical Investigation. May2013, Vol. 123 Issue 5, p2103-2118. 16p. 1 Chart, 9 Graphs.

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Academic Journal

Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice.

Authors : Hanseul Yang¹; Sungsu Lee¹; Seungjoo Lee¹

Subjects: *NEOVASCULARIZATION; *GENETIC transcription regulation; *TRANSCRIPTION factors

Source: Journal of Clinical Investigation. Jan2013, Vol. 123 Issue 1, p418-431. 14p. 2 Color Photographs, 8 Graphs.

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Academic Journal

Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.

Authors : Almotiri, Alhomidi; Alzahrani, Hamed; Menendez-Gonzalez, Juan Bautista

Subjects: HEMATOPOIETIC stem cells; ACUTE myeloid leukemia; ORGANELLE formation

Source: Journal of Clinical Investigation. Jan2021, Vol. 131 Issue 1, p1-17. 17p.

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Academic Journal

LRH-1-dependent glucose sensing determines intermediary metabolism in liver.

Authors : Oosterveer, Maaike H.; Mataki, Chikage; Yamamoto, Hiroyasu

Subjects: CHOLESTEROL; BILE acids; GLUCOKINASE

Source: Journal of Clinical Investigation. Aug2012, Vol. 122 Issue 8, p2817-2826. 10p. 2 Charts, 6 Graphs.

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Academic Journal

TBX5 drives Scn5a expression to regulate cardiac conduction system function.

Authors : Arnolds, David E.; Liu, Fang; Fahrenbach, John P.

Subjects: HEART conduction system; THERAPEUTICS; HEART diseases

Source: Journal of Clinical Investigation. Jul2012, Vol. 122 Issue 7, p2509-2518. 10p. 2 Color Photographs, 1 Black and White Photograph, 3 Charts, 3 Graphs.

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Academic Journal

Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation.

Authors : Guoliang Cui; Xia Qin; Lili Wu

Subjects: T cells; GENETIC regulation; GENETIC transcription regulation

Source: Journal of Clinical Investigation. Feb2011, Vol. 121 Issue 2, p658-670. 13p.

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