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Monoclonal antibody Y01 prevents tauopathy progression induced by lysine 280-acetylated tau in cell and mouse models.

• Authors : Ha-Lim Song; Na-Young Kim; Jaewan Park

Subjects: TAUOPATHIES; TAU proteins; MONOCLONAL antibodies

• Source: Journal of Clinical Investigation. 4/17/2023, Vol. 133 Issue 8, p1-15. 15p.

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Host immunological responses facilitate development of SARS-CoV-2 mutations in patients receiving monoclonal antibody treatments.

• Authors : Gupta, Akshita; Konnova, Angelina; Smet, Mathias

Subjects: MONOCLONAL antibodies; SARS-CoV-2; COVID-19

• Source: Journal of Clinical Investigation. 3/15/2023, Vol. 133 Issue 6, p1-13. 13p.

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The anti-IgE mAb omalizumab induces adverse reactions by engaging Fc[gamma] receptors

• Authors : Balbino, Bianca; Herviou, Pauline; Godon, Ophelie

• Source: Journal of Clinical Investigation. March, 2020, Vol. 130 Issue 3, p1330, 6 p.

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Time to dissect the autoimmune etiology of cancer antibody immunotherapy

• Authors : Dougan, Michael; Pietropaolo, Massimo

• Source: Journal of Clinical Investigation. January, 2020, Vol. 130 Issue 1, p51, 11 p.

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Meant to B: B cells as a therapeutic target in systemic lupus erythematosus.

• Authors : Atisha-Fregoso, Yemil; Toz, Bahtiyar; Diamond, Betty

Subjects: SYSTEMIC lupus erythematosus; B cells; B cell differentiation

• Source: Journal of Clinical Investigation. 6/15/2021, Vol. 131 Issue 12, p1-12. 12p.

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CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification.

• Authors : Okoye, Afam A.; Duell, Derick D.; Fukazawa, Yoshinori

Subjects: T cells; RHESUS monkeys; MONOCLONAL antibodies

• Source: Journal of Clinical Investigation. 4/15/2021, Vol. 131 Issue 8, p1-15. 15p.

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Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion.

• Authors : Salinas, Eduardo; Boisvert, Maude; Upadhyay, Amit A.

Subjects: T helper cells; B cells; HEPATITIS C virus

• Source: Journal of Clinical Investigation. 1/15/2021, Vol. 131 Issue 2, p1-16. 16p. 1 Diagram, 7 Graphs.

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Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface.

• Authors : Dong, Jinhui; Gilchuk, Iuliia; Sheng Li

Subjects: AVIAN influenza A virus; PROTEIN structure; INFLUENZA A virus

• Source: Journal of Clinical Investigation. Sep2020, Vol. 130 Issue 9, p4734-4739. 6p. 4 Graphs.

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Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells.

• Authors : Ningguo Feng; Liya Hu; Siyuan Ding

Subjects: EPITHELIAL cells; RECOMBINANT antibodies; B cells

• Source: Journal of Clinical Investigation. Sep2019, Vol. 129 Issue 9, p3839-3851. 13p.

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HIV-1 latent reservoir size and diversity are stable following brief treatment interruption.

• Authors : Salantes, D. Brenda; Yu Zheng; Mampe, Felicity

Subjects: HIGHLY active antiretroviral therapy; HIV infections; THERAPEUTICS

• Source: Journal of Clinical Investigation. Jul2018, Vol. 128 Issue 7, p3102-3115. 14p. 1 Diagram, 2 Charts, 6 Graphs.

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