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Academic Journal

Zymograph profiling reveals a divergent evolution of sirtuin that may originate from class III enzymes.

  • Authors : Yang Y; CAS Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China; CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Subjects: Sirtuins*/Sirtuins*/Sirtuins*/chemistry ; Evolution, Molecular*; Animals

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Nov; Vol. 299 (11), pp. 105339. Date of Electronic Publication: 2023 Oct 12.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Disruption of sirtuin 7 in zebrafish facilitates hypoxia tolerance.

  • Authors : Liao Q; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China; University of Chinese Academy of Sciences, Beijing, China.

Subjects: Sirtuins*/Sirtuins*/Sirtuins*/genetics ; Sirtuins*/Sirtuins*/Sirtuins*/metabolism ; Zebrafish*/Zebrafish*/Zebrafish*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Aug; Vol. 299 (8), pp. 105074. Date of Electronic Publication: 2023 Jul 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants.

  • Authors : Kalous KS; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Wynia-Smith SL

Subjects: Cysteine/Cysteine/Cysteine/*metabolism ; Oxidants/Oxidants/Oxidants/*metabolism ; Sirtuins/Sirtuins/Sirtuins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Jun 19; Vol. 295 (25), pp. 8524-8536. Date of Electronic Publication: 2020 May 05.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide.

  • Authors : Lee SH; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.; Lee YJ

Subjects: F-Box Proteins*/F-Box Proteins*/F-Box Proteins*/metabolism ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/metabolism ; Sirtuins*/Sirtuins*/Sirtuins*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Mar; Vol. 299 (3), pp. 102909. Date of Electronic Publication: 2023 Jan 13.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease.

  • Authors : Baek J; Department of Internal Medicine-Nephrology, University of Michigan, Ann Arbor, Michigan, USA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.

Subjects: Diabetes Mellitus* ; Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/metabolism ; Sirtuins*/Sirtuins*/Sirtuins*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Mar; Vol. 299 (3), pp. 102960. Date of Electronic Publication: 2023 Feb 02.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

SIRT6 stabilization and cytoplasmic localization in macrophages regulates acute and chronic inflammation in mice.

  • Authors : Bresque M; Laboratory of Metabolic Diseases and Aging, INDICYO Program, Institut Pasteur Montevideo, Montevideo, Uruguay; Laboratory of Vascular Biology and Drug Development, INDICYO Program, Institut Pasteur Montevideo, Montevideo, Uruguay.

Subjects: Inflammation*/Inflammation*/Inflammation*/genetics ; Inflammation*/Inflammation*/Inflammation*/metabolism ; Macrophages*/Macrophages*/Macrophages*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101711. Date of Electronic Publication: 2022 Feb 09.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice.

  • Authors : Bhatt DP; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA; Department of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA.

Subjects: Glutaryl-CoA Dehydrogenase*/Glutaryl-CoA Dehydrogenase*/Glutaryl-CoA Dehydrogenase*/metabolism ; Lysine*/Lysine*/Lysine*/metabolism ; Sirtuins*/Sirtuins*/Sirtuins*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2022 Apr; Vol. 298 (4), pp. 101723. Date of Electronic Publication: 2022 Feb 12.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Nitro-fatty acids as activators of hSIRT6 deacetylase activity.

  • Authors : Carreño M; Laboratorio de Fisicoquímica Biológica, Instituto de Química Biológica, Facultad de Ciencias, and Centro de Investigaciones Biomédicas (CEINBIO), Universidad de la República, Montevideo, Uruguay.; Bresque M

Subjects: Fatty Acids/Fatty Acids/Fatty Acids/*pharmacology ; Nitro Compounds/Nitro Compounds/Nitro Compounds/*pharmacology ; Sirtuins/Sirtuins/Sirtuins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Dec 25; Vol. 295 (52), pp. 18355-18366. Date of Electronic Publication: 2020 Oct 29.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators.

  • Authors : Klein MA; Wisconsin Institute for Discovery, University of Wisconsin, Madison, Wisconsin, USA.; Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.

Subjects: Sirtuins/Sirtuins/Sirtuins/*metabolism ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*pharmacology; Aging/Aging/Aging/physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Aug 07; Vol. 295 (32), pp. 11021-11041. Date of Electronic Publication: 2020 Jun 09.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Mechanism of activation for the sirtuin 6 protein deacylase.

  • Authors : Klein MA; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Wisconsin 53715.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Wisconsin 53715.

Subjects: Histones/Histones/Histones/*metabolism ; Sirtuins/Sirtuins/Sirtuins/*chemistry; Allosteric Regulation/Allosteric Regulation/Allosteric Regulation/drug effects

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Jan 31; Vol. 295 (5), pp. 1385-1399. Date of Electronic Publication: 2019 Dec 10.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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  • 1-10 of  275 results for ""Sirtuins""