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Academic Journal

MGST3 regulates BACE1 protein translation and amyloidogenesis by controlling the RGS4-mediated AKT signaling pathway.

  • Authors : Pu Y; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China; Department of Neurology, Langzhong People's Hospital, Nanchong, Sichuan, China.

Subjects: RGS Proteins*/RGS Proteins*/RGS Proteins*/metabolism ; RGS Proteins*/RGS Proteins*/RGS Proteins*/genetics ; Aspartic Acid Endopeptidases*/Aspartic Acid Endopeptidases*/Aspartic Acid Endopeptidases*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Aug; Vol. 300 (8), pp. 107530. Date of Electronic Publication: 2024 Jul 04.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

RGS4 controls airway hyperresponsiveness through GAP-independent mechanisms.

  • Authors : Joshi IV; Lung and Vascular Inflammation Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.; Chan EC

Subjects: Asthma*/Asthma*/Asthma*/metabolism ; Asthma*/Asthma*/Asthma*/genetics ; Asthma*/Asthma*/Asthma*/pathology

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Apr; Vol. 300 (4), pp. 107127. Date of Electronic Publication: 2024 Mar 02.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Structure-function analysis of plant G-protein regulatory mechanisms identifies key Gα-RGS protein interactions.

Subjects: GTP-Binding Protein alpha Subunits*/GTP-Binding Protein alpha Subunits*/GTP-Binding Protein alpha Subunits*/metabolism ; GTP-Binding Protein alpha Subunits*/GTP-Binding Protein alpha Subunits*/GTP-Binding Protein alpha Subunits*/chemistry ; GTP-Binding Protein alpha Subunits*/GTP-Binding Protein alpha Subunits*/GTP-Binding Protein alpha Subunits*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 May; Vol. 300 (5), pp. 107252. Date of Electronic Publication: 2024 Apr 01.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Self-activating G protein α subunits engage seven-transmembrane regulator of G protein signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri.

  • Authors : Bosch DE; Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA. Electronic address: .; Jeck WR

Subjects: Amoeba* ; Naegleria fowleri*/Naegleria fowleri*/Naegleria fowleri*/metabolism ; RGS Proteins*/RGS Proteins*/RGS Proteins*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2022 Aug; Vol. 298 (8), pp. 102167. Date of Electronic Publication: 2022 Jun 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Regulator of G-protein signaling (RGS) proteins as drug targets: Progress and future potentials.

  • Authors : O'Brien JB; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa, Iowa City, Iowa 52242.; Wilkinson JC

Subjects: GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*metabolism ; RGS Proteins/RGS Proteins/RGS Proteins/*metabolism ; Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Dec 06; Vol. 294 (49), pp. 18571-18585. Date of Electronic Publication: 2019 Oct 21.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Regulator of G protein signaling 2 inhibits Gα q -dependent uveal melanoma cell growth.

  • Authors : Zhang Q; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA.; Haak AJ

Subjects: Melanoma*/Melanoma*/Melanoma*/genetics ; RGS Proteins*/RGS Proteins*/RGS Proteins*/metabolism ; Uveal Neoplasms*/Uveal Neoplasms*/Uveal Neoplasms*/geneticsUveal melanoma

  • Source: The Journal of biological chemistry [J Biol Chem] 2022 Jun; Vol. 298 (6), pp. 101955. Date of Electronic Publication: 2022 Apr 19.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein.

  • Authors : Friedman PA; Laboratory for GPCR Biology, Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: .

Subjects: RGS Proteins*/RGS Proteins*/RGS Proteins*/genetics ; RGS Proteins*/RGS Proteins*/RGS Proteins*/metabolism; Phosphoproteins/Phosphoproteins/Phosphoproteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2022 May; Vol. 298 (5), pp. 101836. Date of Electronic Publication: 2022 Mar 17.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons.

  • Authors : Squires KE; Department of Pharmacology and Chemical Biology, Emory University, Atlanta Georgia, USA.; Gerber KJ

Subjects: Long-Term Potentiation* ; Mutation*; Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100024. Date of Electronic Publication: 2020 Nov 22.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Association with the Plasma Membrane Is Sufficient for Potentiating Catalytic Activity of Regulators of G Protein Signaling (RGS) Proteins of the R7 Subfamily.

  • Authors : Muntean BS; From the Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458.; Martemyanov KA

Subjects: Cell Membrane/Cell Membrane/Cell Membrane/*metabolism ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*genetics ; RGS Proteins/RGS Proteins/RGS Proteins/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Mar 25; Vol. 291 (13), pp. 7195-204. Date of Electronic Publication: 2016 Jan 25.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

High-resolution structure of RGS17 suggests a role for Ca 2+ in promoting the GTPase-activating protein activity by RZ subfamily members.

  • Authors : Sieng M; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907.; Hayes MP

Subjects: Calcium Signaling*; Calcium/Calcium/Calcium/*chemistry ; RGS Proteins/RGS Proteins/RGS Proteins/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 May 17; Vol. 294 (20), pp. 8148-8160. Date of Electronic Publication: 2019 Apr 02.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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