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Academic Journal

Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino acid.

  • Authors : Wennman A; Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Center, SE-751 24 Uppsala, Sweden.; Jernerén F

Subjects: Amino Acids/Amino Acids/Amino Acids/*chemistry ; Iron/Iron/Iron/*chemistry ; Lipoxygenase/Lipoxygenase/Lipoxygenase/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 2012 Sep 14; Vol. 287 (38), pp. 31757-65. Date of Electronic Publication: 2012 Jul 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Stereocontrol of arachidonic acid oxygenation by vertebrate lipoxygenases: newly cloned zebrafish lipoxygenase 1 does not follow the Ala-versus-Gly concept.

  • Authors : Jansen C; Institute of Biochemistry, University Medicine Berlin-Charité, Monbijoustrasse 2, D-10117 Berlin, Germany.; Hofheinz K

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Lipoxygenase/Lipoxygenase/Lipoxygenase/*metabolism ; Zebrafish/Zebrafish/Zebrafish/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2011 Oct 28; Vol. 286 (43), pp. 37804-12. Date of Electronic Publication: 2011 Aug 31.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope.

  • Authors : Zheng Y; Department of Pharmacology and the Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.; Yin H

Subjects: Arachidonate 12-Lipoxygenase/Arachidonate 12-Lipoxygenase/Arachidonate 12-Lipoxygenase/*metabolism ; Ceramides/Ceramides/Ceramides/*metabolism ; Epidermis/Epidermis/Epidermis/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2011 Jul 08; Vol. 286 (27), pp. 24046-56. Date of Electronic Publication: 2011 May 10.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Oxidation of 2-Cys-peroxiredoxins by arachidonic acid peroxide metabolites of lipoxygenases and cyclooxygenase-2.

  • Authors : Cordray P; Department of Pharmacology and Toxicology, and Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.; Doyle K

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/*metabolism ; Cysteine/Cysteine/Cysteine/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2007 Nov 09; Vol. 282 (45), pp. 32623-9. Date of Electronic Publication: 2007 Sep 13.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate.

  • Authors : Brash AR; Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6602, USA.

Subjects: Lipoxygenase/Lipoxygenase/Lipoxygenase/*physiology; Animals ; Catalysis

  • Source: The Journal of biological chemistry [J Biol Chem] 1999 Aug 20; Vol. 274 (34), pp. 23679-82.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Characterization of three potato lipoxygenases with distinct enzymatic activities and different organ-specific and wound-regulated expression patterns.

  • Authors : Royo J; Centro Nacional de Biotecnología CSIC, Campus Cantoblanco UAM, Carretera Colmenar Viejo km. 15,500, 28049 Madrid, Spain.; Vancanneyt G

Subjects: Gene Expression Regulation, Enzymologic*/Gene Expression Regulation, Enzymologic*/Gene Expression Regulation, Enzymologic*/drug effects ; Gene Expression Regulation, Plant*/Gene Expression Regulation, Plant*/Gene Expression Regulation, Plant*/drug effects; Isoenzymes/Isoenzymes/Isoenzymes/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 1996 Aug 30; Vol. 271 (35), pp. 21012-9.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Evaluation of the role of conserved His and Met residues among lipoxygenases by site-directed mutagenesis of recombinant human 5-lipoxygenase.

  • Authors : Nguyen T; Department of Molecular Biology, Merck Frosst Centre for Therapeutic Research, Kirkland, Québec, Canada.; Falgueyret JP

Subjects: Biological Evolution* ; Histidine* ; Methionine*

  • Source: The Journal of biological chemistry [J Biol Chem] 1991 Nov 15; Vol. 266 (32), pp. 22057-62.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

On singular or dual positional specificity of lipoxygenases. The number of chiral products varies with alignment of methylene groups at the active site of the enzyme.

  • Authors : Kühn H; Division of Clinical Pharmacology, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232-6602.; Sprecher H

Subjects: Lipoxygenase/Lipoxygenase/Lipoxygenase/*metabolism; Animals ; Binding Sites

  • Source: The Journal of biological chemistry [J Biol Chem] 1990 Sep 25; Vol. 265 (27), pp. 16300-5.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases.

Subjects: 8,11,14-Eicosatrienoic Acid/8,11,14-Eicosatrienoic Acid/8,11,14-Eicosatrienoic Acid/*blood ; Arachidonic Acids/Arachidonic Acids/Arachidonic Acids/*blood ; Fatty Acids, Unsaturated/Fatty Acids, Unsaturated/Fatty Acids, Unsaturated/*blood

  • Source: The Journal of biological chemistry [J Biol Chem] 1976 Dec 25; Vol. 251 (24), pp. 7816-20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Arachidonic acid 15-lipoxygenase from rabbit peritoneal polymorphonuclear leukocytes. Partial purification and properties.

Subjects: Lipoxygenase/Lipoxygenase/Lipoxygenase/*blood ; Neutrophils/Neutrophils/Neutrophils/*enzymology; Animals

  • Source: The Journal of biological chemistry [J Biol Chem] 1981 Sep 25; Vol. 256 (18), pp. 9583-92.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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