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Academic Journal

Molecular determinants of phospholipid treatment to reduce intracellular cholesterol accumulation in NPC1 deficiency.

  • Authors : Deng S; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA.; Liu TA

Subjects: Cholesterol*/Cholesterol*/Cholesterol*/metabolism ; Niemann-Pick C1 Protein* ; Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Nov; Vol. 300 (11), pp. 107889. Date of Electronic Publication: 2024 Oct 11.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Interaction between the TBC1D24 TLDc domain and the KIBRA C2 domain is disrupted by two epilepsy-associated TBC1D24 missense variants.

  • Authors : Tona R; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Maryland, USA.; Inagaki S

Subjects: Mutation, Missense* ; GTPase-Activating Proteins*/GTPase-Activating Proteins*/GTPase-Activating Proteins*/genetics ; GTPase-Activating Proteins*/GTPase-Activating Proteins*/GTPase-Activating Proteins*/metabolism Digitorenocerebral Syndrome

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Sep; Vol. 300 (9), pp. 107725. Date of Electronic Publication: 2024 Aug 28.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Degradation of STIM1 through FAM134B-mediated ER-phagy is potentially involved in cell proliferation.

  • Authors : Kajiho H; Division of Membrane Dynamics, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan; Department of Biochemical Pathophysiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: .

Subjects: Endoplasmic Reticulum*/Endoplasmic Reticulum*/Endoplasmic Reticulum*/metabolism ; Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/metabolism ; Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/Intracellular Signaling Peptides and Proteins*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Sep; Vol. 300 (9), pp. 107674. Date of Electronic Publication: 2024 Aug 14.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Activation of nemo-like kinase in diamond blackfan anemia suppresses early erythropoiesis by preventing mitochondrial biogenesis.

  • Authors : Wilkes MC; Division of Hematology/Oncology, Department of Pediatrics, Stanford University, Stanford, California, USA; Kabara Cancer Research Institute, Gundersen Medical Foundation, La Crosse, Wisconsin, USA. Electronic address: .

Subjects: Erythropoiesis* ; Anemia, Diamond-Blackfan*/Anemia, Diamond-Blackfan*/Anemia, Diamond-Blackfan*/metabolism ; Anemia, Diamond-Blackfan*/Anemia, Diamond-Blackfan*/Anemia, Diamond-Blackfan*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Aug; Vol. 300 (8), pp. 107542. Date of Electronic Publication: 2024 Jul 09.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

WWC1 upregulation accelerates hyperuricemia by reduction in renal uric acid excretion through Hippo signaling pathway.

  • Authors : Han C; Department of Nephrology, Fujian Clinical Research Center for Chronic Glomerular Disease, The First Affiliated Hospital of Xiamen University, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.; He C

Subjects: Hippo Signaling Pathway* ; Hyperuricemia*/Hyperuricemia*/Hyperuricemia*/metabolism ; Hyperuricemia*/Hyperuricemia*/Hyperuricemia*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Aug; Vol. 300 (8), pp. 107485. Date of Electronic Publication: 2024 Jun 19.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.

  • Authors : Yang Y; School of Life Sciences, Anhui University, Hefei, Anhui, China. Electronic address: .; Xu L

Subjects: Protein Binding*; Mice ; Animals

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107468. Date of Electronic Publication: 2024 Jun 12.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Multi-modal mechanisms of the metastasis suppressor, NDRG1: Inhibition of WNT/β-catenin signaling by stabilization of protein kinase Cα.

  • Authors : Gholam Azad M; Centre for Cancer Cell Biology and Drug Discovery, Griffith University, Brisbane, Queensland, Australia.; Hussaini M

Subjects: beta Catenin*/beta Catenin*/beta Catenin*/metabolism ; beta Catenin*/beta Catenin*/beta Catenin*/genetics ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107417. Date of Electronic Publication: 2024 May 28.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

STAT3 activation of SCAP-SREBP-1 signaling upregulates fatty acid synthesis to promote tumor growth.

  • Authors : Fan Y; Department of Radiation Oncology, Ohio State Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, and College of Medicine at The Ohio State University, Columbus, Ohio, USA; Center for Cancer Metabolism, James Comprehensive Cancer Center at The Ohio State University, Columbus, Ohio, USA.

Subjects: STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/metabolism ; STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/genetics ; Sterol Regulatory Element Binding Protein 1*/Sterol Regulatory Element Binding Protein 1*/Sterol Regulatory Element Binding Protein 1*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107351. Date of Electronic Publication: 2024 May 06.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

African swine fever virus infection regulates pyroptosis by cleaving gasdermin A via active caspase-3 and caspase-4.

  • Authors : Li S; Division of Fundamental Immunology, National African Swine Fever Para-Reference Laboratory, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, Heilongjiang, China.

Subjects: Pyroptosis* ; African Swine Fever Virus*/African Swine Fever Virus*/African Swine Fever Virus*/metabolism ; African Swine Fever*/African Swine Fever*/African Swine Fever*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107307. Date of Electronic Publication: 2024 Apr 22.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Blockade of a novel MAP4K4-LATS2-SASH1-YAP1 cascade inhibits tumorigenesis and metastasis in luminal breast cancer.

  • Authors : Yang P; Clinical Research Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, P. R. China; School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, Guizhou, P. R. China

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/metabolism ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107309. Date of Electronic Publication: 2024 Apr 22.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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  • 1-10 of  521 results for ""Intracellular Signaling Peptides and Proteins genetics""