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Academic Journal

Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol η catalyzed DNA synthesis.

  • Authors : Chang C; Department of Biosciences, Rice University, Houston, Texas, USA.; Zhou G

Subjects: Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/analogs & derivatives ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/chemistry ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/pharmacology

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107361. Date of Electronic Publication: 2024 May 10.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Deciphering the role of Enterococcus faecium cytidine deaminase in gemcitabine resistance of gallbladder cancer.

  • Authors : Jiang L; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China; Department of General Surgery, Shanghai Research Center of Biliary Tract Disease, Shanghai Key Laboratory of Biliary Tract Disease Research, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Subjects: Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/metabolism ; Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/pharmacology ; Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/therapeutic use

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Apr; Vol. 300 (4), pp. 107171. Date of Electronic Publication: 2024 Mar 15.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

5-Ethynyl-2'-deoxycytidine and 5-ethynyl-2'-deoxyuridine are differentially incorporated in cells infected with HSV-1, HCMV, and KSHV viruses.

  • Authors : Manska S; Department of Microbiology and Immunology, University of Nevada, Reno, School of Medicine, Reno, Nevada 89557.; Octaviano R

Subjects: Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*physiology ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives ; Deoxyuridine/Deoxyuridine/Deoxyuridine/*analogs & derivatives

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 May 01; Vol. 295 (18), pp. 5871-5890. Date of Electronic Publication: 2020 Mar 23.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

The DNA repair helicase RECQ1 has a checkpoint-dependent role in mediating DNA damage responses induced by gemcitabine.

  • Authors : Parvathaneni S; Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, D. C. 20059.; Sharma S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*toxicity ; DNA Damage/DNA Damage/DNA Damage/*drug effects ; DNA Repair/DNA Repair/DNA Repair/*drug effects

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Oct 18; Vol. 294 (42), pp. 15330-15345. Date of Electronic Publication: 2019 Aug 23.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe.

  • Authors : Warren NJH; From the Department of Molecular and Systems Biology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire 03756.; Eastman A

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Checkpoint Kinase 1/Checkpoint Kinase 1/Checkpoint Kinase 1/*antagonists & inhibitors ; Cyclin-Dependent Kinase 2/Cyclin-Dependent Kinase 2/Cyclin-Dependent Kinase 2/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Feb 08; Vol. 294 (6), pp. 1763-1778. Date of Electronic Publication: 2018 Dec 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Physical and functional interactions between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity.

  • Authors : Ge Y; Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA.; Jensen TL

Subjects: DNA-Binding Proteins* ; Gene Expression Regulation, Enzymologic* ; Promoter Regions, Genetic*

  • Source: The Journal of biological chemistry [J Biol Chem] 2003 Dec 12; Vol. 278 (50), pp. 49901-10. Date of Electronic Publication: 2003 Sep 26.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage.

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; DNA Damage/DNA Damage/DNA Damage/*drug effects ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives

  • Source: The Journal of biological chemistry [J Biol Chem] 2018 Jan 19; Vol. 293 (3), pp. 984-994. Date of Electronic Publication: 2017 Nov 30.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Oxidative damage to DNA constituents by iron-mediated fenton reactions. The deoxycytidine family.

  • Authors : Luo Y; Division of Biochemistry and Molecular Biology, University of California, Berkeley, California 94720-3202, USA.; Henle ES

Subjects: DNA Damage* ; Oxidative Stress*; Deoxycytidine/Deoxycytidine/Deoxycytidine/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 1996 Aug 30; Vol. 271 (35), pp. 21167-76.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Nucleoside-catabolizing enzymes in mycoplasma-infected tumor cell cultures compromise the cytostatic activity of the anticancer drug gemcitabine.

  • Authors : Vande Voorde J; From the Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, blok x-bus 1030, B-3000 Leuven, Belgium.; Sabuncuoğlu S

Subjects: Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/pharmacokinetics ; Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/Antimetabolites, Antineoplastic*/pharmacology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy

  • Source: The Journal of biological chemistry [J Biol Chem] 2014 May 09; Vol. 289 (19), pp. 13054-65. Date of Electronic Publication: 2014 Mar 25.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Interactions of 2'-modified azido- and haloanalogs of deoxycytidine 5'-triphosphate with the anaerobic ribonucleotide reductase of Escherichia coli.

  • Authors : Eliasson R; Department of Biochemistry 1, MBB, Medical Nobel Institute, Karolinska Institutet, Stockholm, Sweden.; Pontis E

Subjects: Cytidine/Cytidine/Cytidine/*analogs & derivatives ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*pharmacology ; Escherichia coli/Escherichia coli/Escherichia coli/*enzymology

  • Source: The Journal of biological chemistry [J Biol Chem] 1994 Oct 21; Vol. 269 (42), pp. 26116-20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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  • 1-10 of  301 results for ""Deoxycytidine""