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Academic Journal

The Protective Role of Intermedin in Contrast-Induced Acute Kidney Injury: Enhancing Peritubular Capillary Endothelial Cell Adhesion and Integrity Through the cAMP/Rac1 Pathway.

  • Authors : Gao T; The Second Clinical Medical College, Shanxi Medical University, Taiyuan 030000, China.; Gu R

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/chemically induced ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/metabolism ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 16; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Dennd2c Negatively Controls Multinucleation and Differentiation in Osteoclasts by Regulating Actin Polymerization and Protrusion Formation.

  • Authors : Koyanagi Y; Department of Dental Pharmacology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8588, Japan.; Division of Cariology and Restorative Dentistry, Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8588, Japan.

Subjects: Osteoclasts*/Osteoclasts*/Osteoclasts*/metabolism ; Osteoclasts*/Osteoclasts*/Osteoclasts*/cytology ; Cell Differentiation*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 25; Vol. 25 (21). Date of Electronic Publication: 2024 Oct 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Electrostatic Forces Mediate the Specificity of RHO GTPase-GDI Interactions.

  • Authors : Mosaddeghzadeh N; Institute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.; Kazemein Jasemi NS

Subjects: Prenylation/Prenylation/Prenylation/*drug effects ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*chemistry ; rho GTP-Binding Proteins/rho GTP-Binding Proteins/rho GTP-Binding Proteins/*chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 19; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer's Disease.

  • Authors : Wang H; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Nagoya 466-8550, Japan.; Yamahashi Y

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; MicroRNAs*; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 25; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Impaired Insulin Signaling Mediated by the Small GTPase Rac1 in Skeletal Muscle of the Leptin-Deficient Obese Mouse.

  • Authors : Chan MP; Laboratory of Cell Biology, Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, Sakai 599-8531, Japan.; Takenaka N

Subjects: Monomeric GTP-Binding Proteins*/Monomeric GTP-Binding Proteins*/Monomeric GTP-Binding Proteins*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism; Mice

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 16; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Role of ARHGAP1 in Rho GTPase Inactivation during Metastasizing of Breast Cancer Cell Line MCF-7 after Treatment with Doxorubicin.

  • Authors : Géci I; Department of Medical and Clinical Biophysics, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Trieda SNP 1, 04011 Košice, Slovakia.; Bober P

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; GTPase-Activating Proteins*/GTPase-Activating Proteins*/GTPase-Activating Proteins*/metabolism ; rho GTP-Binding Proteins*/rho GTP-Binding Proteins*/rho GTP-Binding Proteins*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 12; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

PGI 2 Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation.

  • Authors : Hirohama D; Division of Clinical Epigenetics, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.; Division of Nephrology, Department of Internal Medicine, Teikyo University School of Medicine, Tokyo 173-8606, Japan.

Subjects: Acute Kidney Injury/Acute Kidney Injury/Acute Kidney Injury/*prevention & control ; Epoprostenol/Epoprostenol/Epoprostenol/*analogs & derivatives ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Jun 22; Vol. 21 (12). Date of Electronic Publication: 2020 Jun 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease.

  • Authors : Tebar F; Departament de Biomedicina, Unitat de Biologia Cel·lular, Facultat de Medicina i Ciències de la Salut, Centre de Recerca Biomèdica CELLEX, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain.; Chavero A

Subjects: Calmodulin/Calmodulin/Calmodulin/*metabolism ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism ; Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 May 23; Vol. 21 (10). Date of Electronic Publication: 2020 May 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Clinical Significance of Combined Epithelial-Mesenchymal Transition Markers Expression and Role of Rac1 in Hepatocellular Carcinoma.

  • Authors : Shin SK; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon 21565, Republic of Korea.; Ryu S

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/metabolism; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 16; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Identification of TIAM1 as a Potential Synthetic-Lethal-like Gene in a Defined Subset of Hepatocellular Carcinoma.

  • Authors : Permtermsin C; Biosciences Institute, Newcastle University Centre for Cancer, Newcastle University, Newcastle NE2 4HH, UK.; Lalchungnunga H

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/metabolism; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 28; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  37 results for ""rac1 GTP-Binding Protein""