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Academic Journal

The Protective Role of Intermedin in Contrast-Induced Acute Kidney Injury: Enhancing Peritubular Capillary Endothelial Cell Adhesion and Integrity Through the cAMP/Rac1 Pathway.

  • Authors : Gao T; The Second Clinical Medical College, Shanxi Medical University, Taiyuan 030000, China.; Gu R

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/chemically induced ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/metabolism ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 16; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Electrostatic Forces Mediate the Specificity of RHO GTPase-GDI Interactions.

  • Authors : Mosaddeghzadeh N; Institute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.; Kazemein Jasemi NS

Subjects: Prenylation/Prenylation/Prenylation/*drug effects ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*chemistry ; rho GTP-Binding Proteins/rho GTP-Binding Proteins/rho GTP-Binding Proteins/*chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 19; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

PGI 2 Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation.

  • Authors : Hirohama D; Division of Clinical Epigenetics, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.; Division of Nephrology, Department of Internal Medicine, Teikyo University School of Medicine, Tokyo 173-8606, Japan.

Subjects: Acute Kidney Injury/Acute Kidney Injury/Acute Kidney Injury/*prevention & control ; Epoprostenol/Epoprostenol/Epoprostenol/*analogs & derivatives ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Jun 22; Vol. 21 (12). Date of Electronic Publication: 2020 Jun 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease.

  • Authors : Tebar F; Departament de Biomedicina, Unitat de Biologia Cel·lular, Facultat de Medicina i Ciències de la Salut, Centre de Recerca Biomèdica CELLEX, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain.; Chavero A

Subjects: Calmodulin/Calmodulin/Calmodulin/*metabolism ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism ; Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 May 23; Vol. 21 (10). Date of Electronic Publication: 2020 May 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Crucial Role for the Small GTPase Rac1 Downstream of the Protein Kinase Akt2 in Insulin Signaling that Regulates Glucose Uptake in Mouse Adipocytes.

  • Authors : Takenaka N; Laboratory of Cell Biology, Department of Biological Science, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan. .; Nakao M

Subjects: Signal Transduction*; Adipocytes/Adipocytes/Adipocytes/*metabolism ; Glucose/Glucose/Glucose/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 Oct 31; Vol. 20 (21). Date of Electronic Publication: 2019 Oct 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Protocadherin-7 Regulates Osteoclast Differentiation through Intracellular SET-Binding Domain-Mediated RhoA and Rac1 Activation.

  • Authors : Kim H; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Takegahara N

Subjects: Cell Differentiation/Cell Differentiation/Cell Differentiation/*physiology ; Neuropeptides/Neuropeptides/Neuropeptides/*metabolism ; Osteoclasts/Osteoclasts/Osteoclasts/*cytology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 04; Vol. 22 (23). Date of Electronic Publication: 2021 Dec 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Atrophy of White Adipose Tissue Accompanied with Decreased Insulin-Stimulated Glucose Uptake in Mice Lacking the Small GTPase Rac1 Specifically in Adipocytes.

  • Authors : Hasegawa K; Laboratory of Cell Biology, Department of Biological Science, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.; Takenaka N

Subjects: Adipose Tissue, White/Adipose Tissue, White/Adipose Tissue, White/*pathology ; Glucose/Glucose/Glucose/*metabolism ; Glucose Transporter Type 4/Glucose Transporter Type 4/Glucose Transporter Type 4/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 05; Vol. 22 (19). Date of Electronic Publication: 2021 Oct 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b.

  • Authors : Melzer C; Biochemistry and Tumor Biology Lab, Department of Obstetrics and Gynecology, Hannover Medical School, Hannover 30625, Germany. .; von der Ohe J

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Transforming Growth Factor beta/Transforming Growth Factor beta/Transforming Growth Factor beta/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2017 Jul 20; Vol. 18 (7). Date of Electronic Publication: 2017 Jul 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Rac1/Wave2/Arp3 Pathway Mediates Rat Blood-Brain Barrier Dysfunction under Simulated Microgravity Based on Proteomics Strategy.

  • Authors : Yan R; School of Life Science, Beijing Institute of Technology, No. 5 Zhongguancun South Street, Haidian District, Beijing 100081, China.; Liu H

Subjects: Gene Expression Regulation*; Actin-Related Protein 3/Actin-Related Protein 3/Actin-Related Protein 3/*metabolism ; Blood-Brain Barrier/Blood-Brain Barrier/Blood-Brain Barrier/*pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 May 13; Vol. 22 (10). Date of Electronic Publication: 2021 May 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Dragon's Blood Regulates Rac1-WAVE2-Arp2/3 Signaling Pathway to Protect Rat Intestinal Epithelial Barrier Dysfunction Induced by Simulated Microgravity.

  • Authors : Li Y; School of Life Science, Beijing Institute of Technology, No.5 Zhongguancun South Street, Haidian District, Beijing 100081, China.; Liu S

Subjects: Actin-Related Protein 2-3 Complex/Actin-Related Protein 2-3 Complex/Actin-Related Protein 2-3 Complex/*metabolism ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*metabolism ; Plant Extracts/Plant Extracts/Plant Extracts/*pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 08; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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