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Academic Journal

The Role of Furin and Its Therapeutic Potential in Cardiovascular Disease Risk.

  • Authors : Fry H; Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Mazidi M

Subjects: Furin*/Furin*/Furin*/metabolism ; Furin*/Furin*/Furin*/genetics ; Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 26; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.

  • Authors : Kubo Y; Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.; Program for Nurturing Global Leaders in Tropical Medicine and Emerging Communicable Diseases, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8523, Japan.

Subjects: Furin*/Furin*/Furin*/metabolism ; Viral Envelope Proteins*/Viral Envelope Proteins*/Viral Envelope Proteins*/metabolism ; Viral Envelope Proteins*/Viral Envelope Proteins*/Viral Envelope Proteins*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 16; Vol. 25 (18). Date of Electronic Publication: 2024 Sep 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Development and Prospects of Furin Inhibitors for Therapeutic Applications.

Subjects: Furin*/Furin*/Furin*/antagonists & inhibitors ; Furin*/Furin*/Furin*/metabolism; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 24; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Screening of Small-Molecule Libraries Using SARS-CoV-2-Derived Sequences Identifies Novel Furin Inhibitors.

  • Authors : Jorkesh A; Department of Pharmaceutical and Pharmacological Science, University of Padova, Via Marzolo, 5, 35131 Padova, Italy.; Department of Biology, University of Padua, Viale G. Colombo 3, 35131 Padova, Italy.

Subjects: Furin*/Furin*/Furin*/antagonists & inhibitors ; Furin*/Furin*/Furin*/metabolism ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects SARS-CoV-2 variants

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 07; Vol. 25 (10). Date of Electronic Publication: 2024 May 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Myelin Basic Protein Attenuates Furin-Mediated Bri2 Cleavage and Postpones Its Membrane Trafficking.

  • Authors : Smirnova EV; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Timofeev VI

Subjects: Membrane Glycoproteins* ; Furin*/Furin*/Furin*/metabolism; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

SARS-CoV-2 S Mutations: A Lesson from the Viral World to Understand How Human Furin Works.

  • Authors : Cassari L; Department of Industrial Engineering, University of Padova, Via Marzolo 9, 35131 Padova, Italy.; Pavan A

Subjects: COVID-19* ; Furin*/Furin*/Furin*/metabolism ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 01; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Identification of Kukoamine A, Zeaxanthin, and Clexane as New Furin Inhibitors.

  • Authors : Zaragoza-Huesca D; Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, CIBERER, Universidad de Murcia, IMIB-Arrixaca, 30003 Murcia, Spain.; Martínez-Cortés C

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Enoxaparin/Enoxaparin/Enoxaparin/*pharmacology ; Furin/Furin/Furin/*antagonists & inhibitors

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 03; Vol. 23 (5). Date of Electronic Publication: 2022 Mar 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Path to Therapeutic Furin Inhibitors: From Yeast Pheromones to SARS-CoV-2.

  • Authors : Thomas G; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.; Couture F

Subjects: Furin*/Furin*/Furin*/metabolism ; COVID-19 Drug Treatment*; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 22; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic β Cells of Mice.

  • Authors : Coppola I; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium.; Brouwers B

Subjects: Furin/Furin/Furin/*deficiency ; Glucose/Glucose/Glucose/*metabolism ; Insulin-Secreting Cells/Insulin-Secreting Cells/Insulin-Secreting Cells/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 14; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

FurinDB: A database of 20-residue furin cleavage site motifs, substrates and their associated drugs.

  • Authors : Tian S; Institute of Biomechanics, School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China; E-Mails: (Q.H.)

Subjects: Databases, Protein* ; Proteolysis*; Furin/Furin/Furin/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2011 Feb 08; Vol. 12 (2), pp. 1060-5. Date of Electronic Publication: 2011 Feb 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  829 results for ""Furin""