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Development and characterization of novel anti‐C5 monoclonal antibodies capable of inhibiting complement in multiple species.

• Authors : Zelek, Wioleta M.¹ (AUTHOR); Taylor, Philip R.¹ (AUTHOR); Morgan, B. Paul¹ (AUTHOR)

Subjects: *ECULIZUMAB; *MONOCLONAL antibodies; *GUINEA pigs

• Source: Immunology. Aug2019, Vol. 157 Issue 4, p283-295. 13p.

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Insights into the molecular basis and mechanism of heme‐triggered TLR4 signalling: The role of heme‐binding motifs in TLR4 and MD2.

• Authors : Hopp, Marie‐T.; Holze, Janine; Lauber, Felicitas

Subjects: TOLL-like receptors; SICKLE cell anemia; BINDING sites

• Source: Immunology; Feb2024, Vol. 171 Issue 2, p181-197, 17p

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Characterizing the original anti‐C5 function‐blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5.

• Authors : Zelek, Wioleta M. (AUTHOR); Menzies, Georgina E. (AUTHOR); Brancale, Andrea (AUTHOR)

Subjects: SPECIES specificity; MONOCLONAL antibodies; MOUSE diseases

• Source: Immunology. Oct2020, Vol. 161 Issue 2, p103-113. 11p.

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From functions to mechanisms of the prototypic complement C5 antibody BB5.1.

• Authors : Milling, Simon¹ (AUTHOR)

Subjects: *LICENSED products; *IMMUNOGLOBULINS; *ECULIZUMAB

• Source: Immunology. Oct2020, Vol. 161 Issue 2, p81-82. 2p.

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Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19.

• Authors : Siggins MK; Davies K ...

Subjects: COVID-19*; Humans ; Complement Activation

• Source: Immunology [Immunology] 2023 Mar; Vol. 168 (3), pp. 473-492. Date of Electronic Publication: 2022 Nov 28.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet

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Complement: Functions, location and implications.

• Authors : Kareem, Samer (AUTHOR); Jacob, Alexander (AUTHOR); Mathew, John (AUTHOR)

Subjects: COMPLEMENT activation; IMMUNE complexes; IMMUNE system

• Source: Immunology. Oct2023, Vol. 170 Issue 2, p180-192. 13p.

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Session 11: Immunoglobulin function and therapeutic applications.

Subjects: IMMUNE response; IMMUNOLOGICAL adjuvants; MONOCLONAL antibodies

• Source: Immunology. Mar2007 Supplement, Vol. 120, p41-44. 4p.

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Complement activation by human IgG antibodies to galactose‐α‐1,3‐galactose.

• Authors : Bernth Jensen, Jens Magnus (AUTHOR); Laursen, Nick Stub (AUTHOR); Jensen, Rasmus Kjeldsen (AUTHOR)

Subjects: COMPLEMENT activation; GALACTOSE; IMMUNOGLOBULINS

• Source: Immunology. Sep2020, Vol. 161 Issue 1, p66-79. 14p.

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Characterizing a pH‐switch anti‐C5 antibody as a tool for human and mouse complement C5 purification and cross‐species inhibition of classical and reactive lysis.

• Authors : Zelek, Wioleta M.; Stott, Matthew; Walters, David

Subjects: LYSINS; MONOCLONAL antibodies; ANTIGENS

• Source: Immunology. Nov2018, Vol. 155 Issue 3, p396-403. 8p.

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Complementing the inflammasome.

• Authors : Triantafilou, Martha; Hughes, Timothy R.; Morgan, Bryan Paul

Subjects: INFLAMMASOMES; NATURAL immunity; IMMUNE system

• Source: Immunology. Feb2016, Vol. 147 Issue 2, p152-164. 13p.

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