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Academic Journal

The benzoylphenylurea derivative BPU17 acts as an inhibitor of prohibitin and exhibits antifibrotic activity.

  • Authors : Hayashi K; Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Minami-Kogushi 1-1-1, Ube, Yamaguchi, 755-8505, Japan. Electronic address: .; Kobayashi M

Subjects: Prohibitins* ; Repressor Proteins*/Repressor Proteins*/Repressor Proteins*/metabolism ; Myofibroblasts*/Myofibroblasts*/Myofibroblasts*/drug effects

  • Source: Experimental cell research [Exp Cell Res] 2024 Sep 01; Vol. 442 (1), pp. 114221. Date of Electronic Publication: 2024 Aug 23.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

SPARC-YAP/TAZ inhibition prevents the fibroblasts-myofibroblasts transformation.

  • Authors : Du J; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai Clinical Research Center for Eye Diseases, Shanghai Key Clinical Specialty, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.

Subjects: Myofibroblasts*/Myofibroblasts*/Myofibroblasts*/metabolism ; Fibronectins*/Fibronectins*/Fibronectins*/metabolism; Humans

  • Source: Experimental cell research [Exp Cell Res] 2023 Aug 01; Vol. 429 (1), pp. 113649. Date of Electronic Publication: 2023 May 22.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.

  • Authors : Zhao Z; Department of Gynecology and Obstetrics, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China.; Han W

Subjects: Extracellular Matrix*/Extracellular Matrix*/Extracellular Matrix*/metabolism ; Myofibroblasts*/Myofibroblasts*/Myofibroblasts*/metabolism ; Cytoskeletal Proteins*/Cytoskeletal Proteins*/Cytoskeletal Proteins*/metabolism

  • Source: Experimental cell research [Exp Cell Res] 2024 Mar 15; Vol. 436 (2), pp. 113974. Date of Electronic Publication: 2024 Feb 10.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tbx18-positive cells-derived myofibroblasts contribute to renal interstitial fibrosis via transforming growth factor-β signaling.

  • Authors : Yuan X; Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Zhang L

Subjects: Fibrosis/Fibrosis/Fibrosis/*metabolism ; Myofibroblasts/Myofibroblasts/Myofibroblasts/*metabolism ; T-Box Domain Proteins/T-Box Domain Proteins/T-Box Domain Proteins/*metabolism

  • Source: Experimental cell research [Exp Cell Res] 2021 Aug 15; Vol. 405 (2), pp. 112682. Date of Electronic Publication: 2021 Jun 10.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Resveratrol decreases TNFα-induced ICAM-1 expression and release by Sirt-1-independent mechanism in intestinal myofibroblasts.

  • Authors : Domazetovic V; Department of Biomedical, Experimental and Clinical Sciences 'Mario Serio', University of Florence, Viale Morgagni 50, 50134, Florence, Italy.; Bonanomi AG

Subjects: Intercellular Adhesion Molecule-1/Intercellular Adhesion Molecule-1/Intercellular Adhesion Molecule-1/*metabolism ; Intestines/Intestines/Intestines/*cytology ; Myofibroblasts/Myofibroblasts/Myofibroblasts/*metabolism

  • Source: Experimental cell research [Exp Cell Res] 2019 Sep 15; Vol. 382 (2), pp. 111479. Date of Electronic Publication: 2019 Jun 21.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Curcumin induces differential expression of cytoprotective enzymes but similar apoptotic responses in fibroblasts and myofibroblasts.

  • Authors : Lundvig DMS; Department of Orthodontics and Craniofacial Biology, Radboud university medical center, Nijmegen, The Netherlands.; Pennings SWC

Subjects: Cytoprotection*; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*pharmacology ; Antioxidants/Antioxidants/Antioxidants/*pharmacology

  • Source: Experimental cell research [Exp Cell Res] 2015 Jan 15; Vol. 330 (2), pp. 429-441. Date of Electronic Publication: 2014 Oct 17.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition.

  • Authors : Muir AB; Division of Gastroenterology, Hepatology, and Nutrition, The Children׳s Hospital of Philadelphia, Philadelphia, PA 19104 USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104 USA. Electronic address: .

Subjects: Epithelial-Mesenchymal Transition*; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Myofibroblasts/Myofibroblasts/Myofibroblasts/*metabolism

  • Source: Experimental cell research [Exp Cell Res] 2015 Jan 01; Vol. 330 (1), pp. 102-10. Date of Electronic Publication: 2014 Aug 27.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Redox regulation of MMP-3/TIMP-1 ratio in intestinal myofibroblasts: effect of N-acetylcysteine and curcumin.

  • Authors : Fontani F; Dipartimento di Scienze Biomediche Sperimentali e Cliniche (Sezione Biochimica), Università degli Studi di Firenze, viale Morgagni 50, 50134 Firenze, Italia.; Marcucci T

Subjects: Acetylcysteine/Acetylcysteine/Acetylcysteine/*pharmacology ; Crohn Disease/Crohn Disease/Crohn Disease/*enzymology ; Curcumin/Curcumin/Curcumin/*pharmacology

  • Source: Experimental cell research [Exp Cell Res] 2014 Apr 15; Vol. 323 (1), pp. 77-86. Date of Electronic Publication: 2014 Feb 26.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

p75 neurotrophin receptor regulates NGF-induced myofibroblast differentiation and collagen synthesis through MRTF-A.

  • Authors : Liu Z; Department of Oral and Maxillofacial Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, China.; Cao Y

Subjects: Cell Differentiation/Cell Differentiation/Cell Differentiation/*drug effects ; Collagen/Collagen/Collagen/*metabolism ; Myofibroblasts/Myofibroblasts/Myofibroblasts/*cytology

  • Source: Experimental cell research [Exp Cell Res] 2019 Oct 01; Vol. 383 (1), pp. 111504. Date of Electronic Publication: 2019 Jul 17.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model.

  • Authors : Jiang S; Department of Joint and Trauma Surgery, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou 510630, China.; He R

Subjects: Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/drug effects; Contracture/Contracture/Contracture/*metabolism ; Contracture/Contracture/Contracture/*pathology

  • Source: Experimental cell research [Exp Cell Res] 2018 Aug 15; Vol. 369 (2), pp. 325-334. Date of Electronic Publication: 2018 May 30.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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