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  • 1-6 of  6 results for ""Cyclic Nucleotide Phosphodiesterases, Type 2""

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Publication : european journal of pharmacology
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Academic Journal

Phosphodiesterase-2 inhibitor reverses post-traumatic stress induced fear memory deficits and behavioral changes via cAMP/cGMP pathway.

  • Authors : Chen L; Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310006, PR China; Brain Institute, School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.

Subjects: Fear*; Behavior, Animal/Behavior, Animal/Behavior, Animal/*drug effects ; Brain/Brain/Brain/*drug effects

  • Source: European journal of pharmacology [Eur J Pharmacol] 2021 Jan 15; Vol. 891, pp. 173768. Date of Electronic Publication: 2020 Dec 01.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pharmacological characterization of a novel potent, selective, and orally active phosphodiesterase 2A inhibitor, PDM-631.

  • Authors : Maehara S; Discovery Research, Mochida Pharmaceutical Co., Ltd., 722 Uenohara, Jimba, Gotemba, Shizuoka 412-8524, Japan. Electronic address: .; Arakawa K

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*antagonists & inhibitors ; Pyrazoles/Pyrazoles/Pyrazoles/*administration & dosage ; Pyrazoles/Pyrazoles/Pyrazoles/*pharmacology

  • Source: European journal of pharmacology [Eur J Pharmacol] 2017 Sep 15; Vol. 811, pp. 110-116. Date of Electronic Publication: 2017 Jun 03.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Bay 60-7550, a PDE2 inhibitor, exerts positive inotropic effect of rat heart by increasing PKA-mediated phosphorylation of phospholamban.

  • Authors : Wang YW; National Standard Laboratory of Pharmacology for Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.; Gao QW

Subjects: Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*metabolism ; Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*antagonists & inhibitors

  • Source: European journal of pharmacology [Eur J Pharmacol] 2021 Jun 15; Vol. 901, pp. 174077. Date of Electronic Publication: 2021 Mar 31.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Characterisation of Lu AF33241: A novel, brain-penetrant, dual inhibitor of phosphodiesterase (PDE) 2A and PDE10A.

  • Authors : Redrobe JP; Neuroscience Research DK, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Copenhagen, Denmark. Electronic address: .; Rasmussen LK

Subjects: Antipsychotic Agents/Antipsychotic Agents/Antipsychotic Agents/*pharmacology ; Behavior, Animal/Behavior, Animal/Behavior, Animal/*drug effects ; Blood-Brain Barrier/Blood-Brain Barrier/Blood-Brain Barrier/*metabolism

  • Source: European journal of pharmacology [Eur J Pharmacol] 2015 Aug 15; Vol. 761, pp. 79-85. Date of Electronic Publication: 2015 May 02.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion.

  • Authors : van Donkelaar EL; Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands. ; Rutten K

Subjects: Phosphodiesterase 5 Inhibitors*; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*antagonists & inhibitors ; Memory/Memory/Memory/*drug effects

  • Source: European journal of pharmacology [Eur J Pharmacol] 2008 Dec 14; Vol. 600 (1-3), pp. 98-104. Date of Electronic Publication: 2008 Oct 21.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Time-dependent involvement of cAMP and cGMP in consolidation of object memory: studies using selective phosphodiesterase type 2, 4 and 5 inhibitors.

  • Authors : Rutten K; Department of Psychiatry and Neuropsychology, Brain and Behavior Institute, EURON, Maastricht University, 6200 MD Maastricht, The Netherlands. ; Prickaerts J

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*antagonists & inhibitors ; 3',5'-Cyclic-GMP Phosphodiesterases/3',5'-Cyclic-GMP Phosphodiesterases/3',5'-Cyclic-GMP Phosphodiesterases/*antagonists & inhibitors ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*physiology

  • Source: European journal of pharmacology [Eur J Pharmacol] 2007 Mar 08; Vol. 558 (1-3), pp. 107-12. Date of Electronic Publication: 2006 Dec 01.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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  • 1-6 of  6 results for ""Cyclic Nucleotide Phosphodiesterases, Type 2""