Search Results

Display Settings
Results per page: 10
Sort By: Relevance
Filter
  • 1-10 of  248 results for ""CARBONIC anhydrase inhibitors""

Your Filters

Publication : european journal of medicinal chemistry
Reset filters
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments.

  • Authors : Hefny SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt. Electronic address: .; El-Moselhy TF

Subjects: Sulfonamides*/Sulfonamides*/Sulfonamides*/pharmacology ; Sulfonamides*/Sulfonamides*/Sulfonamides*/chemistry ; Sulfonamides*/Sulfonamides*/Sulfonamides*/chemical synthesis

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Aug 05; Vol. 274, pp. 116527. Date of Electronic Publication: 2024 May 24.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Exploring novel anticancer pyrazole benzenesulfonamides featuring tail approach strategy as carbonic anhydrase inhibitors.

  • Authors : Ahmed RF; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.; Mahmoud WR

Subjects: Carbonic Anhydrase Inhibitors*/Carbonic Anhydrase Inhibitors*/Carbonic Anhydrase Inhibitors*/chemistry ; Carbonic Anhydrases*/Carbonic Anhydrases*/Carbonic Anhydrases*/metabolism; Humans

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2023 Dec 05; Vol. 261, pp. 115805. Date of Electronic Publication: 2023 Sep 19.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Probing benzenesulfonamide-thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase II.

  • Authors : Gamal MA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St, Cairo, 11562, Egypt.; Fahim SH

Subjects: Carbonic Anhydrase II*/Carbonic Anhydrase II*/Carbonic Anhydrase II*/antagonists & inhibitors ; Carbonic Anhydrase II*/Carbonic Anhydrase II*/Carbonic Anhydrase II*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/drug therapy

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 May 05; Vol. 271, pp. 116434. Date of Electronic Publication: 2024 Apr 20.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Development of 4-((3-oxo-3-phenylpropyl)amino)benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors.

  • Authors : Elbadawi MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.; Eldehna WM

Subjects: Carbonic Anhydrase II* ; Carbonic Anhydrase Inhibitors*/Carbonic Anhydrase Inhibitors*/Carbonic Anhydrase Inhibitors*/chemistry ; Carbonic Anhydrase Inhibitors*/Carbonic Anhydrase Inhibitors*/Carbonic Anhydrase Inhibitors*/pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2022 Aug 05; Vol. 238, pp. 114412. Date of Electronic Publication: 2022 Apr 27.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Natural inspired ligustrazine-based SLC-0111 analogues as novel carbonic anhydrase inhibitors.

  • Authors : Elimam DM; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Subjects: Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*pharmacology ; Biological Products/Biological Products/Biological Products/*pharmacology ; Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/*pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2022 Jan 15; Vol. 228, pp. 114008. Date of Electronic Publication: 2021 Nov 27.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors.

  • Authors : Abdel-Mohsen HT; Department of Chemistry of Natural and Microbial Products, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Buhouth St., Dokki, P.O. Box 12622, Cairo, Egypt. Electronic address: .; El Kerdawy AM

Subjects: Drug Design*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/*pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2022 Jan 15; Vol. 228, pp. 114004. Date of Electronic Publication: 2021 Nov 20.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Synthesis, biological evaluation, and in silico studies of potential activators of apoptosis and carbonic anhydrase inhibitors on isatin-5-sulfonamide scaffold.

  • Authors : Krymov SK; Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, Moscow, 119021, Russia.; Scherbakov AM

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/*pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2022 Jan 15; Vol. 228, pp. 113997. Date of Electronic Publication: 2021 Nov 17.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity.

  • Authors : Chiaramonte N; University of Florence, Department of Neuroscience, Psychology, Drug Research and Child's Health (NEUROFARBA), Section of Pharmaceutical and Nutraceutical Sciences, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.; Angeli A

Subjects: Molecular Dynamics Simulation*; Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/*pharmacology ; Carbonic Anhydrases/Carbonic Anhydrases/Carbonic Anhydrases/*metabolism

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2022 Jan 15; Vol. 228, pp. 114026. Date of Electronic Publication: 2021 Dec 04.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Chalcogenides-incorporating carbonic anhydrase inhibitors concomitantly reverted oxaliplatin-induced neuropathy and enhanced antiproliferative action.

  • Authors : Tanini D; University of Florence, Department of Chemistry 'Ugo Schiff', Via Della Lastruccia 3-13, I-50019, Sesto Fiorentino, Italy.; Carradori S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/Carbonic Anhydrase Inhibitors/*pharmacology ; Carbonic Anhydrases/Carbonic Anhydrases/Carbonic Anhydrases/*metabolism

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2021 Dec 05; Vol. 225, pp. 113793. Date of Electronic Publication: 2021 Aug 23.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation.

  • Authors : Elimam DM; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt; School of Chemistry and Biosciences, Faculty of Life Sciences, University of Bradford, Bradford, United Kingdom.

Subjects: Drug Design*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Biological Products/Biological Products/Biological Products/*pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2021 Dec 05; Vol. 225, pp. 113800. Date of Electronic Publication: 2021 Aug 25.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
  • 1-10 of  248 results for ""CARBONIC anhydrase inhibitors""