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Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures.

• Authors : Zoll S; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.; Stanchev S

Subjects: Models, Molecular* ; Molecular Dynamics Simulation*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology

• Source: The EMBO journal [EMBO J] 2014 Oct 16; Vol. 33 (20), pp. 2408-21. Date of Electronic Publication: 2014 Sep 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.

• Authors : Bode W; Max-Planck-Institut für Biochemie, Martinsried, FRG.; Mayr I

Subjects: Amino Acid Chloromethyl Ketones* ; Antithrombins* ; Thrombin*

• Source: The EMBO journal [EMBO J] 1989 Nov; Vol. 8 (11), pp. 3467-75.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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Agricola

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Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

• Authors : Hetz C; Serono Pharmaceutical Research Institute, 14 Chemin des Aulx, 1228 Plan les Ouates, Switzerland.; Russelakis-Carneiro M

Subjects: Caspases/Caspases/Caspases/*metabolism ; Endoplasmic Reticulum/Endoplasmic Reticulum/Endoplasmic Reticulum/*physiology ; PrPSc Proteins/PrPSc Proteins/PrPSc Proteins/*toxicity

• Source: The EMBO journal [EMBO J] 2003 Oct 15; Vol. 22 (20), pp. 5435-45.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.

• Authors : Renatus M; Max-Planck-Institute of Biochemistry, Department of Structural Research, Martinsried, Germany. ; Engh RA

Subjects: Protein Conformation*; Lysine/Lysine/Lysine/*chemistry ; Tissue Plasminogen Activator/Tissue Plasminogen Activator/Tissue Plasminogen Activator/*chemistry

• Source: The EMBO journal [EMBO J] 1997 Aug 15; Vol. 16 (16), pp. 4797-805.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

• Authors : Li PF; Department of Cardiology, Franz Volhard Klinik, Universitätskliuikum Charité, Humboldt University, Wiltbergstrasse 50, 13125 Berlin, Germany.; Dietz R

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cytochrome c Group/Cytochrome c Group/Cytochrome c Group/*metabolism ; Mitochondria/Mitochondria/Mitochondria/*drug effects

• Source: The EMBO journal [EMBO J] 1999 Nov 01; Vol. 18 (21), pp. 6027-36.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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Neisserial porin (PorB) causes rapid calcium influx in target cells and induces apoptosis by the activation of cysteine proteases.

• Authors : Müller A; Max-Planck-Institut für Infektionsbiologie, Abteilung Molekulare Biologie, Monbijoustrasse 2, 10117 Berlin, Germany.; Günther D

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/*metabolism ; Calcium/Calcium/Calcium/*metabolism

• Source: The EMBO journal [EMBO J] 1999 Jan 15; Vol. 18 (2), pp. 339-52.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2.

• Authors : Grandgirard D; Institute of Medical Microbiology, University of Berne, Friedbuehlstrasse 51, CH-3010 Berne, Switzerland.; Studer E

Subjects: Caspases*; Apoptosis/Apoptosis/Apoptosis/*physiology ; Cysteine Endopeptidases/Cysteine Endopeptidases/Cysteine Endopeptidases/*metabolism

• Source: The EMBO journal [EMBO J] 1998 Aug 10; Vol. 17 (5), pp. 1268-78.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis.

• Authors : Gross A; Division of Molecular Oncology, Departments of Medicine and Pathology, Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, MO 63110, USA.; Jockel J

Subjects: Caspases*; Apoptosis/Apoptosis/Apoptosis/*physiology ; Mitochondria/Mitochondria/Mitochondria/*physiology

• Source: The EMBO journal [EMBO J] 1998 Jul 15; Vol. 17 (14), pp. 3878-85.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1.

• Authors : Graves JD; Department of Immunology, University of Washington Medical Center, Seattle, WA 98109, USA.; Gotoh Y

Subjects: Apoptosis* ; Caspases* ; Saccharomyces cerevisiae Proteins*

• Source: The EMBO journal [EMBO J] 1998 Apr 15; Vol. 17 (8), pp. 2224-34.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print Cited Medium: Print ISSN: 0261-4189

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