Search Results

Display Settings
Results per page: 10
Sort By: Relevance
Filter
  • 1-10 of  16 results for ""Liver-Specific Organic Anion Transporter 1""

Your Filters

Publication : clinical pharmacokinetics
Reset filters
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Physiologically Based Pharmacokinetic Model of OATP1B Substrates with a Nonlinear Mixed Effect Approach: Estimating Empirical In Vitro-to-In Vivo Scaling Factors.

  • Authors : Li R; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Cambridge, MA, 02139, USA. .; Kimoto E

Subjects: Models, Biological* ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/metabolism ; Nonlinear Dynamics*

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Aug; Vol. 63 (8), pp. 1177-1189. Date of Electronic Publication: 2024 Aug 19.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

Record details

Read More Add to Saved list
×
Academic Journal

Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.

  • Authors : Türk D; Clinical Pharmacy, Saarland University, Campus C2 2, 66123, Saarbrücken, Germany.; Hanke N

Subjects: Models, Biological*; Cytochrome P-450 CYP2C8/Cytochrome P-450 CYP2C8/Cytochrome P-450 CYP2C8/*drug effects ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*drug effects

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2019 Dec; Vol. 58 (12), pp. 1595-1607.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic)

Record details

Read More Add to Saved list
×
Academic Journal

Clinical Investigation of Coproporphyrins as Sensitive Biomarkers to Predict Mild to Strong OATP1B-Mediated Drug-Drug Interactions.

  • Authors : Kunze A; Janssen Pharmaceutical Companies of Johnson & Johnson, Turnhoutseweg 30, 2340, Beerse, Belgium. .; Ediage EN

Subjects: Coproporphyrins/Coproporphyrins/Coproporphyrins/*blood ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors ; Solute Carrier Organic Anion Transporter Family Member 1B3/Solute Carrier Organic Anion Transporter Family Member 1B3/Solute Carrier Organic Anion Transporter Family Member 1B3/*antagonists & inhibitors

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2018 Dec; Vol. 57 (12), pp. 1559-1570.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic)

Record details

Read More Add to Saved list
×
Academic Journal

Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis.

  • Authors : Li R; Systems Modeling and Simulation, Medicine Design, World Wide Research and Development, Pfizer Inc., Cambridge, MA, USA. .; Barton HA

Subjects: Gene Frequency* ; Models, Biological* ; Pharmacogenomic Variants*

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2018 Apr; Vol. 57 (4), pp. 491-503.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic)

Record details

Read More Add to Saved list
×
Academic Journal

Clinical Evaluation of the Effect of Encorafenib on Bupropion, Rosuvastatin, and Coproporphyrin I and Considerations for Statin Coadministration.

Subjects: Bupropion*/Bupropion*/Bupropion*/administration & dosage ; Bupropion*/Bupropion*/Bupropion*/pharmacokinetics ; Carbamates*/Carbamates*/Carbamates*/administration & dosage

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Apr; Vol. 63 (4), pp. 483-496. Date of Electronic Publication: 2024 Feb 29.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

Record details

Read More Add to Saved list
×
Academic Journal

Irinotecan-Induced Toxicity: A Pharmacogenetic Study Beyond UGT1A1.

  • Authors : de With M; Department of Medical Oncology, Erasmus Medical Center Cancer Institute, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Department of Clinical Chemistry, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.

Subjects: Camptothecin*/Camptothecin*/Camptothecin*/adverse effects ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/adverse effects; Humans

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 Nov; Vol. 62 (11), pp. 1589-1597. Date of Electronic Publication: 2023 Sep 16.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

Record details

Read More Add to Saved list
×
Academic Journal

Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance.

  • Authors : Hovd M; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Blindern, PO 1068, 0316, Oslo, Norway. .; Robertsen I

Subjects: Gastric Bypass*/Gastric Bypass*/Gastric Bypass*/methods ; Obesity, Morbid*; Humans

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 May; Vol. 62 (5), pp. 725-735. Date of Electronic Publication: 2023 Mar 29.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

Record details

Read More Add to Saved list
×
Academic Journal

The Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid: Systematic Review and Meta-analysis.

  • Authors : Na Takuathung M; Department of Pharmacology, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Road, Sriphoom, Muang, Chiang Mai, 50200, Thailand.; Sakuludomkan W

Subjects: Kidney Transplantation* ; Mycophenolic Acid*/Mycophenolic Acid*/Mycophenolic Acid*/pharmacology; Area Under Curve

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2021 Oct; Vol. 60 (10), pp. 1291-1302. Date of Electronic Publication: 2021 Jun 09.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

Record details

Read More Add to Saved list
×
Academic Journal

Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

  • Authors : Yin A; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.; Leiden Network for Personalized Therapeutics, Leiden University Medical Center, Leiden, The Netherlands.

Subjects: Adrenal Cortex Neoplasms*/Adrenal Cortex Neoplasms*/Adrenal Cortex Neoplasms*/drug therapy ; Adrenal Cortex Neoplasms*/Adrenal Cortex Neoplasms*/Adrenal Cortex Neoplasms*/genetics ; Adrenal Cortex Neoplasms*/Adrenal Cortex Neoplasms*/Adrenal Cortex Neoplasms*/metabolism

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2021 Jan; Vol. 60 (1), pp. 89-102.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic)

Record details

Read More Add to Saved list
×
Academic Journal

Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8.

  • Authors : Tod M; Pharmacie, Groupement Hospitalier Nord, Hospices Civils de Lyon, Lyon, France. .; EMR3738, Faculté de médecine Lyon-sud, Université Lyon 1, BP 12, Chemin du grand revoyet, 69921, Oullins, France. .

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/metabolism; Cytochromes/Cytochromes/Cytochromes/*metabolism ; Organic Anion Transporters/Organic Anion Transporters/Organic Anion Transporters/*metabolism

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2020 Jun; Vol. 59 (6), pp. 757-770.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic)

Record details

Read More Add to Saved list
×
  • 1-10 of  16 results for ""Liver-Specific Organic Anion Transporter 1""