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Editorial & Opinion

Comment on: "CYP3A4*22 Genotype‑Guided Dosing of Kinase Inhibitors in Cancer Patients".

  • Authors : Oude Munnink TH; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen and University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. .; Klein SK

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Jun; Vol. 63 (6), pp. 917-918. Date of Electronic Publication: 2024 May 11.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Intrasubject Variability in Intravenous and Oral Probes for Hepatic and First-Pass CYP3A Activity.

  • Authors : Kharasch ED; Department of Anesthesiology, Duke University School of Medicine, 905 S. LaSalle St, GSRB1 Room 2031, Box 3094, Durham, NC, 27710, USA. .; Bermaride LLC, Durham, NC, 27712, USA. .

Subjects: Midazolam*/Midazolam*/Midazolam*/pharmacokinetics ; Midazolam*/Midazolam*/Midazolam*/administration & dosage ; Midazolam*/Midazolam*/Midazolam*/blood

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Aug; Vol. 63 (8), pp. 1121-1135. Date of Electronic Publication: 2024 Jul 29.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers.

  • Authors : Rohr BS; Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Medical Faculty of Heidelberg, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; Krohmer E

Subjects: Ritonavir*/Ritonavir*/Ritonavir*/administration & dosage ; Ritonavir*/Ritonavir*/Ritonavir*/pharmacokinetics ; Ritonavir*/Ritonavir*/Ritonavir*/pharmacology

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Apr; Vol. 63 (4), pp. 469-481. Date of Electronic Publication: 2024 Feb 23.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

CYP3A and CYP2C19 Activity Determined by Microdosed Probe Drugs Accurately Predict Voriconazole Clearance in Healthy Adults.

  • Authors : Muhareb A; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; Blank A

Subjects: Midazolam*/Midazolam*/Midazolam*/pharmacokinetics ; Cytochrome P-450 CYP3A*; Humans

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 Sep; Vol. 62 (9), pp. 1305-1314. Date of Electronic Publication: 2023 Jul 28.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients.

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 Aug; Vol. 62 (8), pp. 1129-1139. Date of Electronic Publication: 2023 Jun 13.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Intraindividual Variability in Absolute Bioavailability and Clearance of Midazolam in Healthy Individuals.

  • Authors : Kvitne KE; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Blindern, P.O. Box 1068, 0316, Oslo, Norway. .; Drevland OM

Subjects: Midazolam* ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism; Male

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 Jul; Vol. 62 (7), pp. 981-987. Date of Electronic Publication: 2023 May 10.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Integrated Use of In Vitro and In Vivo Information for Comprehensive Prediction of Drug Interactions Due to Inhibition of Multiple CYP Isoenzymes.

  • Authors : Hozuki S; Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.; Yoshioka H

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Isoenzymes*; Humans

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 Jun; Vol. 62 (6), pp. 849-860. Date of Electronic Publication: 2023 Apr 19.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Estimation of FMO3 Ontogeny by Mechanistic Population Pharmacokinetic Modelling of Risdiplam and Its Impact on Drug-Drug Interactions in Children.

  • Authors : Cleary Y; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Grenzacherstrasse 124, 4070, Basel, Switzerland. .; Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, UK. .

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Models, Biological*; Adult

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 Jun; Vol. 62 (6), pp. 891-904. Date of Electronic Publication: 2023 May 06.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

General Framework to Quantitatively Predict Pharmacokinetic Induction Drug-Drug Interactions Using In Vitro Data.

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism; Humans

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2023 May; Vol. 62 (5), pp. 737-748. Date of Electronic Publication: 2023 Mar 29.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion.

  • Authors : Nassar YM; Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universität Berlin, Kelchstr. 31, 12169, Berlin, Germany.; Graduate Research Training Program PharMetrX, Freie Universität Berlin/University of Potsdam, Berlin/Potsdam, Germany.

Subjects: Midazolam*/Midazolam*/Midazolam*/pharmacokinetics ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism; Humans

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2022 Nov; Vol. 61 (11), pp. 1595-1607. Date of Electronic Publication: 2022 Oct 04.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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  • 1-10 of  171 results for ""Cytochrome P-450 CYP3A""