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Academic Journal

Ciprofol is primarily glucuronidated by UGT1A9 and predicted not to cause drug-drug interactions with typical substrates of CYP1A2, CYP2B6, and CYP2C19.

  • Authors : Hou L; Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Zhao Y

Subjects: Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/metabolism ; Microsomes, Liver*/Microsomes, Liver*/Microsomes, Liver*/metabolism; Humans

  • Source: Chemico-biological interactions [Chem Biol Interact] 2024 Jan 05; Vol. 387, pp. 110811. Date of Electronic Publication: 2023 Nov 20.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Triphenyl phosphate induces clastogenic effects potently in mammalian cells, human CYP1A2 and 2E1 being major activating enzymes.

  • Authors : Xie J; Department of Toxicology, School of Public Health (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 1023 S. Shatai Road, Guangzhou, 510515, China.; Tu H

Subjects: Mutagens*/Mutagens*/Mutagens*/toxicity ; Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/genetics; Cricetinae

  • Source: Chemico-biological interactions [Chem Biol Interact] 2023 Jan 05; Vol. 369, pp. 110259. Date of Electronic Publication: 2022 Nov 10.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

1-Methylpyrene induces chromosome loss and mitotic apparatus damage in a Chinese hamster V79-derived cell line expressing both human CYP1A2 and sulfotransferase 1A1.

  • Authors : Yu H; Department of Toxicology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), 1023 S. Shatai Road, Guangzhou, 510515, China.; Li Z

Subjects: Arylsulfotransferase/Arylsulfotransferase/Arylsulfotransferase/*metabolism ; Chromosomes, Mammalian/Chromosomes, Mammalian/Chromosomes, Mammalian/*metabolism ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*metabolism

  • Source: Chemico-biological interactions [Chem Biol Interact] 2020 Dec 01; Vol. 332, pp. 109283. Date of Electronic Publication: 2020 Oct 06.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Identification and characterization of reactive metabolites in myristicin-mediated mechanism-based inhibition of CYP1A2.

  • Authors : Yang AH; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China.; He X

Subjects: Benzyl Compounds/Benzyl Compounds/Benzyl Compounds/*pharmacology ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*drug effects ; Cytochrome P-450 CYP1A2 Inhibitors/Cytochrome P-450 CYP1A2 Inhibitors/Cytochrome P-450 CYP1A2 Inhibitors/*pharmacology

  • Source: Chemico-biological interactions [Chem Biol Interact] 2015 Jul 25; Vol. 237, pp. 133-40. Date of Electronic Publication: 2015 Jun 16.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor.

  • Authors : Belic A; Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, Sl-1000 Ljubljana, Slovenia.; Tóth K

Subjects: Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*genetics ; Dehydroepiandrosterone/Dehydroepiandrosterone/Dehydroepiandrosterone/*pharmacology ; Hepatocytes/Hepatocytes/Hepatocytes/*drug effects

  • Source: Chemico-biological interactions [Chem Biol Interact] 2013 May 25; Vol. 203 (3), pp. 597-603. Date of Electronic Publication: 2013 Apr 17.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Metabolic activation of phenanthrene by human and mouse cytochromes P450 and pharmacokinetics in CYP1A2 knockout mice.

  • Authors : Schober W; Division of Environmental Dermatology and Allergy, Helmholtz Zentrum München/TUM, ZAUM - Center for Allergy and Environment, Technische Universität München, Biedersteiner Strasse 29, 80802 Munich, Germany. ; Pusch G

Subjects: Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism ; Phenanthrenes/Phenanthrenes/Phenanthrenes/*toxicity

  • Source: Chemico-biological interactions [Chem Biol Interact] 2010 Jan 05; Vol. 183 (1), pp. 57-66.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print Cited Medium: Internet ISSN: 1872-7786 (Electronic)

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Academic Journal

Effects of quercetin on beta-apo-8'-carotenal-induced DNA damage and cytochrome P1A2 expression in A549 cells.

  • Authors : Yeh SL; Institute of Nutritional Science, Chung Shan Medical University, No. 110 Section 1 Chien-Kuo N. Road, Taichung, Taiwan, ROC. ; Wu SH

Subjects: DNA Breaks*; Benzo(a)pyrene/Benzo(a)pyrene/Benzo(a)pyrene/*metabolism ; Carotenoids/Carotenoids/Carotenoids/*metabolism

  • Source: Chemico-biological interactions [Chem Biol Interact] 2006 Nov 07; Vol. 163 (3), pp. 199-206. Date of Electronic Publication: 2006 Aug 12.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0009-2797

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Academic Journal

TSU-16, (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, is a potent activator of aryl hydrocarbon receptor and increases CYP1A1 and CYP1A2 expression in human hepatocytes.

  • Authors : Matsuoka-Kawano K; Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan. ; Yoshinari K

Subjects: Angiogenesis Inhibitors/Angiogenesis Inhibitors/Angiogenesis Inhibitors/*pharmacology ; Cytochrome P-450 CYP1A1/Cytochrome P-450 CYP1A1/Cytochrome P-450 CYP1A1/*genetics ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*genetics

  • Source: Chemico-biological interactions [Chem Biol Interact] 2010 Apr 15; Vol. 185 (1), pp. 33-41. Date of Electronic Publication: 2010 Feb 18.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Hyper- and hypo-induction of cytochrome P450 activities with Aroclor 1254 and 3-methylcholanthrene in Cyp1a2(-/-) mice.

  • Authors : Barker ML; University of Utah, Department of Pharmacology and Toxicology, Salt Lake City, UT 84112, United States.; Hathaway LB

Subjects: Chlorodiphenyl (54% Chlorine)/Chlorodiphenyl (54% Chlorine)/Chlorodiphenyl (54% Chlorine)/*pharmacology ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism

  • Source: Chemico-biological interactions [Chem Biol Interact] 2009 Dec 10; Vol. 182 (2-3), pp. 220-6. Date of Electronic Publication: 2009 Sep 20.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes.

  • Authors : Vrzal R; Department of Cell Biology and Genetic, Faculty of Science, Palacky University, Slechtitelu 11, 783 71 Olomouc, Czech Republic.; Stejskalova L

Subjects: Cytochrome P-450 CYP1A1/Cytochrome P-450 CYP1A1/Cytochrome P-450 CYP1A1/*metabolism ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*metabolism ; Dexamethasone/Dexamethasone/Dexamethasone/*pharmacology

  • Source: Chemico-biological interactions [Chem Biol Interact] 2009 May 15; Vol. 179 (2-3), pp. 288-96. Date of Electronic Publication: 2008 Nov 05.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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  • 1-10 of  52 results for ""Cytochrome P-450 CYP1A2""