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  • 1-10 of  34 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""

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Academic Journal

Alteration of vascular reactivity in heart failure: role of phosphodiesterases 3 and 4.

  • Authors : Hubert F; Faculté de Pharmacie, Inserm UMR-S 769, LabEx LERMIT-DHU TORINO, Châtenay-Malabry, France; Faculté de Pharmacie, Université Paris-Sud, Châtenay-Malabry, France

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*physiology ; Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/*physiology ; Heart Failure/Heart Failure/Heart Failure/*physiopathology

  • Source: British journal of pharmacology [Br J Pharmacol] 2014 Dec; Vol. 171 (23), pp. 5361-75.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN: 1476-5381 (Electronic)

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Academic Journal

Regulation of I Ca,L and force by PDEs in human-induced pluripotent stem cell-derived cardiomyocytes.

  • Authors : Saleem U; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Center for Heart Research (DZHK), Hamburg, Germany.

Subjects: Induced Pluripotent Stem Cells* ; Myocytes, Cardiac*; Adult

  • Source: British journal of pharmacology [Br J Pharmacol] 2020 Jul; Vol. 177 (13), pp. 3036-3045. Date of Electronic Publication: 2020 Mar 31.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

PDE3, but not PDE4, reduces β₁ - and β₂-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients.

  • Authors : Molenaar P; Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia.; Christ T

Subjects: Adrenergic beta-1 Receptor Antagonists/Adrenergic beta-1 Receptor Antagonists/Adrenergic beta-1 Receptor Antagonists/*adverse effects ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Heart Failure/Heart Failure/Heart Failure/*drug therapy

  • Source: British journal of pharmacology [Br J Pharmacol] 2013 Jun; Vol. 169 (3), pp. 528-38.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN: 1476-5381 (Electronic)

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Academic Journal

The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release.

  • Authors : Ong WK; Strathclyde Institute of Pharmacy, Cell Biology Group, University of Strathclyde, Glasgow, UK.; Gribble FM

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*physiology ; Glucagon-Like Peptide 1/Glucagon-Like Peptide 1/Glucagon-Like Peptide 1/*metabolism ; Isoenzymes/Isoenzymes/Isoenzymes/*physiology

  • Source: British journal of pharmacology [Br J Pharmacol] 2009 Jun; Vol. 157 (4), pp. 633-44. Date of Electronic Publication: 2009 Apr 09.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Cigarette smoke up-regulates PDE3 and PDE4 to decrease cAMP in airway cells.

  • Authors : Zuo H; Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, GRIAC, Groningen, The Netherlands.

Subjects: Smoke* ; Tobacco Products*; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism

  • Source: British journal of pharmacology [Br J Pharmacol] 2018 Jul; Vol. 175 (14), pp. 2988-3006. Date of Electronic Publication: 2018 Jun 03.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

In permanent atrial fibrillation, PDE3 reduces force responses to 5-HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias.

  • Authors : Berk E; Department of Pharmacology, Dresden University of Technology, Dresden, Germany.; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Subjects: Arrhythmias, Cardiac/Arrhythmias, Cardiac/Arrhythmias, Cardiac/*metabolism ; Atrial Fibrillation/Atrial Fibrillation/Atrial Fibrillation/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism

  • Source: British journal of pharmacology [Br J Pharmacol] 2016 Aug; Vol. 173 (16), pp. 2478-89. Date of Electronic Publication: 2016 Jul 18.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

PDE4 in the human heart - major player or little helper?

  • Authors : Eschenhagen T; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, Germany.

Subjects: Adrenergic beta-1 Receptor Antagonists/Adrenergic beta-1 Receptor Antagonists/Adrenergic beta-1 Receptor Antagonists/*adverse effects ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Heart Failure/Heart Failure/Heart Failure/*drug therapy

  • Source: British journal of pharmacology [Br J Pharmacol] 2013 Jun; Vol. 169 (3), pp. 524-7.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN: 1476-5381 (Electronic)

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Academic Journal

Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle.

  • Authors : Afzal F; Department of Pharmacology, Faculty of Medicine, University of Oslo, Norway.; Aronsen JM

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/*metabolism ; Heart Ventricles/Heart Ventricles/Heart Ventricles/*physiopathology

  • Source: British journal of pharmacology [Br J Pharmacol] 2011 Jan; Vol. 162 (1), pp. 54-71.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Internet ISSN: 1476-5381 (Electronic)

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Academic Journal

Dual PDE3/4 inhibitors as therapeutic agents for chronic obstructive pulmonary disease.

  • Authors : Banner KH; Novartis Institute for Biomedical Research, Horsham, West Sussex, RH12 5AB, UK. ; Press NJ

Subjects: Phosphodiesterase 3 Inhibitors* ; Phosphodiesterase 4 Inhibitors*; Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/*administration & dosage

  • Source: British journal of pharmacology [Br J Pharmacol] 2009 Jul; Vol. 157 (6), pp. 892-906. Date of Electronic Publication: 2009 Jun 05.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Ontogenic changes of the control by phosphodiesterase-3 and -4 of 5-HT responses in porcine heart and relevance to human atrial 5-HT(4) receptors.

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*physiology ; Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/*physiology ; Heart Rate/Heart Rate/Heart Rate/*drug effects

  • Source: British journal of pharmacology [Br J Pharmacol] 2009 Jan; Vol. 156 (2), pp. 237-49. Date of Electronic Publication: 2009 Jan 19.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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  • 1-10 of  34 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""