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Academic Journal

IDH2-NADPH pathway protects against acute pancreatitis via suppressing acinar cell ferroptosis.

  • Authors : Peng Q; Department of Gastroenterology, Shanghai General Hospital, Shanghai, China.; Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; Pancreatitis*/Pancreatitis*/Pancreatitis*/metabolism ; Pancreatitis*/Pancreatitis*/Pancreatitis*/chemically induced

  • Source: British journal of pharmacology [Br J Pharmacol] 2024 Oct; Vol. 181 (20), pp. 4067-4084. Date of Electronic Publication: 2024 Jul 27.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

ABT-199 (Venetoclax), a BH3-mimetic Bcl-2 inhibitor, does not cause Ca 2+ -signalling dysregulation or toxicity in pancreatic acinar cells.

  • Authors : Jakubowska MA; Medical Research Council Group, School of Biosciences, Cardiff University, Cardiff, UK.; International Associated Laboratory (LIA), Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.

Subjects: Acinar Cells/Acinar Cells/Acinar Cells/*drug effects ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*pharmacology

  • Source: British journal of pharmacology [Br J Pharmacol] 2019 Nov; Vol. 176 (22), pp. 4402-4415. Date of Electronic Publication: 2018 Nov 08.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Ibuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells upon inflammatory injury and mitogenic stimulation.

  • Authors : Bombardo M; Swiss Hepato-Pancreato-Biliary Center, Department of Visceral and Transplantation Surgery, University Hospital of Zurich, Zurich, Switzerland.; Malagola E

Subjects: Acinar Cells/Acinar Cells/Acinar Cells/*drug effects ; Diclofenac/Diclofenac/Diclofenac/*pharmacology ; Ibuprofen/Ibuprofen/Ibuprofen/*pharmacology

  • Source: British journal of pharmacology [Br J Pharmacol] 2018 Jan; Vol. 175 (2), pp. 335-347. Date of Electronic Publication: 2017 Jun 16.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Role of calcium in substance P-induced chemokine synthesis in mouse pancreatic acinar cells.

Subjects: PANCREATIC acinar cells; CALCIUM; CHEMOKINES

  • Source: British Journal of Pharmacology; Jul2008, Vol. 154 Issue 6, p1339-1348, 10p, 1 Diagram, 6 Graphs

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Academic Journal

Acinar cell NLRP3 inflammasome and gasdermin D (GSDMD) activation mediates pyroptosis and systemic inflammation in acute pancreatitis.

Subjects: CELL death; NLRP3 protein; PYROPTOSIS

  • Source: British Journal of Pharmacology; Sep2021, Vol. 178 Issue 17, p3533-3552, 20p, 8 Color Photographs, 1 Black and White Photograph, 1 Illustration

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Academic Journal

Intraglandular application of botulinum toxin leads to structural and functional changes in rat acinar cells.

Subjects: BOTULINUM toxin; PANCREATIC acinar cells; LABORATORY rats

  • Source: British Journal of Pharmacology; Sep2007, Vol. 152 Issue 1, p161-167, 7p, 5 Black and White Photographs, 1 Chart, 1 Graph

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