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EXPRESSION OF CONCERN: HSP70 Inhibition Reverses Cell Adhesion Mediated and Acquired Drug Resistance in Multiple Myeloma.

  • Source: British journal of haematology [Br J Haematol] 2024 Dec 17. Date of Electronic Publication: 2024 Dec 17.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

E2F2 modulates cell adhesion through the transcriptional regulation of PECAM1 in multiple myeloma.

  • Authors : Chen SN; Department of Hematology, Institute of Hematology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.; Key Laboratory for Efficacy and Safety Evaluation of Hematological Malignancy Targeted Medicine of Guangdong Provincial Drug Administration, School of Medicine, Sun Yat-Sen University, Shenzhen, China.

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics; Humans ; Animals

  • Source: British journal of haematology [Br J Haematol] 2023 Aug; Vol. 202 (4), pp. 840-855. Date of Electronic Publication: 2023 Jun 26.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Sickle red blood cell-derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor.

  • Authors : An R; Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Biomedical Engineering, University of Houston, Houston, Texas, USA.

Subjects: Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/pathology ; Anemia, Sickle Cell*; Humans

  • Source: British journal of haematology [Br J Haematol] 2023 May; Vol. 201 (3), pp. 552-563. Date of Electronic Publication: 2023 Jan 05.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

CXCR4 antagonists disrupt leukaemia-meningeal cell adhesion and attenuate chemoresistance.

  • Authors : Jonart LM; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.

Subjects: Drug Resistance, Neoplasm* ; Leukemia*; Humans

  • Source: British journal of haematology [Br J Haematol] 2023 May; Vol. 201 (3), pp. 459-469. Date of Electronic Publication: 2022 Dec 19.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Antithrombin-III mitigates thrombin-mediated endothelial cell contraction and sickle red blood cell adhesion in microscale flow.

  • Authors : Wulftange WJ; Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, Ohio, USA.; Kucukal E

Subjects: Anemia, Sickle Cell* ; Thrombin*/Thrombin*/Thrombin*/metabolism ; Thrombin*/Thrombin*/Thrombin*/pharmacology

  • Source: British journal of haematology [Br J Haematol] 2022 Sep; Vol. 198 (5), pp. 893-902. Date of Electronic Publication: 2022 Jul 13.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Longitudinal assessment of adhesion to vascular cell adhesion molecule-1 at steady state and during vaso-occlusive crises in sickle cell disease.

  • Authors : White J; Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI, USA.; Functional Fluidics, Children's Hospital of Michigan, Detroit, MI, USA.

Subjects: Anemia, Sickle Cell/Anemia, Sickle Cell/Anemia, Sickle Cell/*genetics ; Vascular Cell Adhesion Molecule-1/Vascular Cell Adhesion Molecule-1/Vascular Cell Adhesion Molecule-1/*metabolism; Case-Control Studies

  • Source: British journal of haematology [Br J Haematol] 2022 Feb; Vol. 196 (4), pp. 1052-1058. Date of Electronic Publication: 2021 Dec 01.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Combination of a mitogen-activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion-based residual disease and prevents re-expansion of FLT3-ITD acute myeloid leukaemia.

  • Authors : Zabkiewicz J; Academic Department of Haematology, University of Cardiff, H, eath Park, Cardiff, UK.; Lazenby M

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/enzymology ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics

  • Source: British journal of haematology [Br J Haematol] 2020 Oct; Vol. 191 (2), pp. 231-242. Date of Electronic Publication: 2020 May 11.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Editorial & Opinion

Sevuparin blocks sickle blood cell adhesion and sickle-leucocyte rolling on immobilized L-selectin in a dose dependent manner.

  • Authors : White J; Division of Pediatric Critical Care Medicine, Wayne State University School of Medicine, Detroit, MI, USA.; Functional Fluidics, Detroit, MI, USA.

Subjects: Anemia, Sickle Cell/Anemia, Sickle Cell/Anemia, Sickle Cell/*metabolism ; Heparin/Heparin/Heparin/*analogs & derivatives ; Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/Human Umbilical Vein Endothelial Cells/*metabolism

  • Source: British journal of haematology [Br J Haematol] 2019 Mar; Vol. 184 (5), pp. 873-876. Date of Electronic Publication: 2018 May 16.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma.

  • Authors : Waldschmidt JM; Department of Haematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Simon A

Subjects: Drug Resistance, Neoplasm*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cell Adhesion/Cell Adhesion/Cell Adhesion/*drug effects

  • Source: British journal of haematology [Br J Haematol] 2017 Oct; Vol. 179 (1), pp. 36-49. Date of Electronic Publication: 2017 Jul 02.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Report

ZAP70 expression directly promotes chronic lymphocytic leukaemia cell adhesion to bone marrow stromal cells.

  • Authors : Lafarge ST; Department of Immunology, University of Manitoba, Winnipeg, MB, Canada; Cancercare Manitoba, Manitoba Institute of Cell Biology, Winnipeg, MB, Canada.

Subjects: Gene Expression*; Leukemia, Lymphocytic, Chronic, B-Cell/Leukemia, Lymphocytic, Chronic, B-Cell/Leukemia, Lymphocytic, Chronic, B-Cell/*metabolism ; Mesenchymal Stem Cells/Mesenchymal Stem Cells/Mesenchymal Stem Cells/*metabolism

  • Source: British journal of haematology [Br J Haematol] 2015 Jan; Vol. 168 (1), pp. 139-42. Date of Electronic Publication: 2014 Aug 04.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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