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Publication : british journal of clinical pharmacology
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Academic Journal

Involvement of CYP1A2 in mexiletine metabolism.

  • Authors : Nakajima M; Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Showa University, Tokyo, Japan.; Kobayashi K

Subjects: Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/*pharmacokinetics ; Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/Cytochrome P-450 CYP1A2/*metabolism ; Mexiletine/Mexiletine/Mexiletine/*pharmacokinetics

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1998 Jul; Vol. 46 (1), pp. 55-62.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

Influence of the CYP2D6*10 allele on the metabolism of mexiletine by human liver microsomes.

  • Authors : Senda C; Department of Drug Metabolism and Pharmacokinetics, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co, Hyogo.; Yamaura Y

Subjects: Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/*pharmacokinetics ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*genetics ; Mexiletine/Mexiletine/Mexiletine/*pharmacokinetics

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2001 Jul; Vol. 52 (1), pp. 100-3.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

The metabolism of mexiletine in relation to the debrisoquine/sparteine-type polymorphism of drug oxidation.

  • Authors : Broly F; Laboratoire de Pharmacologie, Faculté de Médecine de Lille, France.; Vandamme N

Subjects: Debrisoquin/Debrisoquin/Debrisoquin/*metabolism ; Mexiletine/Mexiletine/Mexiletine/*metabolism ; Sparteine/Sparteine/Sparteine/*metabolism

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1991 Oct; Vol. 32 (4), pp. 459-66.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

Dose independent pharmacokinetics of mexiletine in healthy volunteers.

Subjects: Mexiletine/Mexiletine/Mexiletine/*blood ; Propylamines/Propylamines/Propylamines/*blood; Administration, Oral

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1986 Mar; Vol. 21 (3), pp. 319-21.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

The clinical pharmacology of mexiletine.

Subjects: Mexiletine/Mexiletine/Mexiletine/*blood ; Propylamines/Propylamines/Propylamines/*blood; Administration, Oral

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1978 Aug; Vol. 6 (2), pp. 103-8.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

Mexiletine disposition: individual variation in response to urine acidification and alkalinisation.

Subjects: Mexiletine/Mexiletine/Mexiletine/*metabolism ; Propylamines/Propylamines/Propylamines/*metabolism ; Urine/Urine/Urine/*analysis

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1983 Sep; Vol. 16 (3), pp. 281-4.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

The effect of spontaneous changes in urinary pH on mexiletine plasma concentrations and excretion during chronic administration to healthy volunteers.

Subjects: Mexiletine/Mexiletine/Mexiletine/*metabolism ; Propylamines/Propylamines/Propylamines/*metabolism ; Urine/Urine/Urine/*physiology

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1979 Oct; Vol. 8 (4), pp. 349-52.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

A comparison of mexiletine and a slow release formulation of mexiletine in patients admitted to a coronary care unit [proceedings].

Subjects: Arrhythmias, Cardiac/Arrhythmias, Cardiac/Arrhythmias, Cardiac/*drug therapy ; Coronary Disease/Coronary Disease/Coronary Disease/*drug therapy ; Mexiletine/Mexiletine/Mexiletine/*therapeutic use

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1980 Mar; Vol. 9 (3), pp. 293P.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

Mexiletine in normal volunteers.

Subjects: Mexiletine/Mexiletine/Mexiletine/*blood ; Propylamines/Propylamines/Propylamines/*blood; Administration, Oral

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1978 Oct; Vol. 6 (4), pp. 372-3.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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Academic Journal

Absorption of mexiletine after treatment with gastric antacids.

Subjects: Antacids/Antacids/Antacids/*pharmacology ; Intestinal Absorption/Intestinal Absorption/Intestinal Absorption/*drug effects ; Mexiletine/Mexiletine/Mexiletine/*metabolism

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 1982 Nov; Vol. 14 (5), pp. 746-7.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Print ISSN: 0306-5251 (Print)

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  • 1-10 of  99 results for ""MEXILETINE""