Search Results

Filter
  • 1-10 of  11 results for ""Adrenergic alpha-1 Receptor Agonists""
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Discovery of potent α1L-adrenoceptor agonists: Design and synthesis of bicyclic derivatives.

  • Authors : Suzuki S; Pharmaceutical Research Laboratories, Toray Industries, Inc., 6-10-1 Tebiro, Kamakura, Kanagawa 248-8555, Japan. Electronic address: .; Okano T

Subjects: Drug Discovery*; Adrenergic alpha-1 Receptor Agonists/Adrenergic alpha-1 Receptor Agonists/Adrenergic alpha-1 Receptor Agonists/*chemical synthesis ; Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*chemical synthesis

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Aug 15; Vol. 25 (16), pp. 3368-72. Date of Electronic Publication: 2015 May 31.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

6,7-Dihydro-5H-pyrrolo[1,2-a] imidazoles as potent and selective alpha1A adrenoceptor partial agonists.

  • Authors : Roberts LR; Department of Chemistry, Pfizer Global Research and Development, Sandwich Labs, Sandwich, Kent, UK. ; Fish PV

Subjects: Adrenergic alpha-1 Receptor Agonists*; Imidazoles/Imidazoles/Imidazoles/*chemistry ; Imidazoles/Imidazoles/Imidazoles/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Jun 01; Vol. 19 (11), pp. 3113-7. Date of Electronic Publication: 2009 Apr 18.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

Potent and selective alpha1A adrenoceptor partial agonists--novel imidazole frameworks.

  • Authors : Whitlock GA; Pfizer Global Research and Development, Sandwich Labs, Sandwich, Kent, UK. ; Brennan PE

Subjects: Adrenergic alpha-1 Receptor Agonists*; Imidazoles/Imidazoles/Imidazoles/*chemistry; ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Jun 01; Vol. 19 (11), pp. 3118-21. Date of Electronic Publication: 2009 Apr 07.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

Novel 2-imidazoles as potent, selective and CNS penetrant alpha1A adrenoceptor partial agonists.

  • Authors : Roberts LR; Department of Chemistry, Pfizer Global Research and Development, Sandwich Labs, IPC432, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK. ; Bryans J

Subjects: Adrenergic alpha-1 Receptor Agonists*; Central Nervous System/Central Nervous System/Central Nervous System/*drug effects ; Chemistry, Pharmaceutical/Chemistry, Pharmaceutical/Chemistry, Pharmaceutical/*methods

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2008 Dec 15; Vol. 18 (24), pp. 6437-40. Date of Electronic Publication: 2008 Oct 19.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

Novel 2-imidazoles as potent and selective alpha1A adrenoceptor partial agonists.

  • Authors : Whitlock GA; Department of Chemistry, Pfizer Global Research and Development, Sandwich Labs, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK. ; Conlon K

Subjects: Adrenergic alpha-1 Receptor Agonists*; Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*therapeutic use ; Imidazoles/Imidazoles/Imidazoles/*therapeutic use

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2008 May 01; Vol. 18 (9), pp. 2930-4. Date of Electronic Publication: 2008 Mar 29.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: alpha1a subtype selective 2'-heteroaryl compounds.

  • Authors : Speake JD; GlaxoSmithKline, 5Moore Drive, Research Triangle Park, NC 27709, USA. ; Navas F

Subjects: Adrenergic alpha-1 Receptor Agonists*; Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*chemical synthesis ; Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2003 Mar 24; Vol. 13 (6), pp. 1183-6.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X

Record details

×
Academic Journal

Alpha(1)-adrenoceptor activation: a comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines.

  • Authors : Hodson SJ; GlaxoSmithKline Research and Development, Research Triangle Park, NC 27709, USA.; Bigham EC

Subjects: Adrenergic alpha-1 Receptor Agonists*; Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*chemistry ; Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2002 Dec 02; Vol. 12 (23), pp. 3449-52.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X

Record details

×
Academic Journal

alpha(1)-Adrenoceptor agonists: the identification of novel alpha(1A )subtype selective 2'-heteroaryl-2-(phenoxymethyl)imidazolines.

  • Authors : Bishop MJ; GlaxoSmithKline Research and Development, 5 Moore Drive, Research Triangle Park, NC 27709, ; Barvian KA

Subjects: Adrenergic alpha-1 Receptor Agonists*; Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*pharmacology ; Imidazoles/Imidazoles/Imidazoles/*chemical synthesis

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2002 Feb 11; Vol. 12 (3), pp. 471-5.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X

Record details

×
Academic Journal

New piperidinyl- and 1,2,3,6-tetrahydropyridinyl-pyrimidine derivatives as selective 5-HT1A receptor agonists with highly potent anti-ischemic effects.

  • Authors : Kamei K; Daiichi Suntory Biomedical Research Co., Ltd, 1-1-1, Wakayamadai, Shimamoto-cho, Mishima-gun, Osaka 618-8513, Japan. ; Maeda N

Subjects: Serotonin 5-HT1 Receptor Agonists*; Cerebrovascular Circulation/Cerebrovascular Circulation/Cerebrovascular Circulation/*drug effects ; Neuroprotective Agents/Neuroprotective Agents/Neuroprotective Agents/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2005 Jun 15; Vol. 15 (12), pp. 2990-3.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X

Record details

×
Academic Journal

2-(anilinomethyl)imidazolines as alpha1A adrenergic receptor agonists: 2'-heteroaryl and 2'-oxime ether series.

  • Authors : Navas F 3rd; Division of Chemistry, GlaxoSmithKline, 5Moore Drive, Research Triangle Park, NC 27709, USA. ; Bishop MJ

Subjects: Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*chemical synthesis ; Imidazoles/Imidazoles/Imidazoles/*pharmacology; Adrenergic alpha-1 Receptor Agonists

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2002 Feb 25; Vol. 12 (4), pp. 575-9.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X

Record details

×
  • 1-10 of  11 results for ""Adrenergic alpha-1 Receptor Agonists""