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Linker and Conjugation Site Synergy in Antibody–Drug Conjugates: Impacts on Biological Activity.

• Authors : Aoyama, Michihiko; Tada, Minoru; Yokoo, Hidetomo

• Source: Bioconjugate Chemistry; 10/16/2024, Vol. 35 Issue 10, p1568-1576, 9p

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A New Age of Drug Delivery: A Comparative Perspective of Ferritin–Drug Conjugates (FDCs) and Antibody–Drug Conjugates (ADCs).

• Authors : Hong, Juanji; Li, Kang; He, Jiuyang

• Source: Bioconjugate Chemistry; 8/21/2024, Vol. 35 Issue 8, p1142-1147, 6p

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Late-Stage Desulfurization Enables Rapid and Efficient Solid-Phase Synthesis of Cathepsin-Cleavable Linkers for Antibody–Drug Conjugates.

• Authors : Ahangarpour, Marzieh; Brimble, Margaret A.; Kavianinia, Iman

• Source: Bioconjugate Chemistry; 7/17/2024, Vol. 35 Issue 7, p1007-1014, 8p

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Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody–Drug Conjugates.

• Authors : Zhang, Alan; Seiss, Katherine; Laborde, Laurent

• Source: Bioconjugate Chemistry; 2/21/2024, Vol. 35 Issue 2, p140-146, 7p

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The Evolving Landscape of Antibody–Drug Conjugates: In Depth Analysis of Recent Research Progress.

• Authors : Sasso, Janet M.; Tenchov, Rumiana; Bird, Robert

• Source: Bioconjugate Chemistry; 11/15/2023, Vol. 34 Issue 11, p1951-2000, 50p

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Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody–Drug Conjugates.

• Authors : Marvin, Christopher C.; Hobson, Adrian D.; McPherson, Michael

• Source: Bioconjugate Chemistry; 10/18/2023, Vol. 34 Issue 10, p1835-1850, 16p

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One-Pot Assembly of Dual-Site-Specific Antibody–Drug Conjugates via Glycan Remodeling and Affinity-Directed Traceless Conjugation.

• Authors : Tang, Caihong; Zeng, Yue; Zhang, Jianxin

• Source: Bioconjugate Chemistry; 4/19/2023, Vol. 34 Issue 4, p748-755, 8p

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Generation of DAR1 Antibody-Drug Conjugates for Ultrapotent Payloads Using Tailored GlycoConnect Technology.

• Authors : de Bever, Laureen; Popal, Sorraya; van Schaik, Jord

• Source: Bioconjugate Chemistry; 3/15/2023, Vol. 34 Issue 3, p538-548, 11p

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Selective Reduction of Cysteine Mutant Antibodies for Site-Specific Antibody-Drug Conjugates.

• Authors : Liao X; Process Chemistry, Small Molecule CMC Development, AbbVie Inc., North Chicago, Illinois 60064, United States.; Haight A

Subjects: Immunoconjugates*/Immunoconjugates*/Immunoconjugates*/chemistry; Cysteine/Cysteine/Cysteine/chemistry ; Reducing Agents

• Source: Bioconjugate chemistry [Bioconjug Chem] 2023 Dec 20; Vol. 34 (12), pp. 2293-2301. Date of Electronic Publication: 2023 Nov 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet

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A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity.

• Authors : Rady, Tony; Turelli, Lorenzo; Nothisen, Marc

• Source: Bioconjugate Chemistry; 10/19/2022, Vol. 33 Issue 10, p1860-1866, 7p

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