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Academic Journal

Proton bridging in the interactions of thrombin with small inhibitors.

  • Authors : Kovach IM; Department of Chemistry, The Catholic University of America, Washington, D.C. 20064, USA. ; Kelley P

Subjects: Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/chemistry ; Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/metabolism ; Protons*

  • Source: Biochemistry [Biochemistry] 2009 Aug 04; Vol. 48 (30), pp. 7296-304.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.

  • Authors : Arni RK; Department of Chemistry, Michigan State University, East Lansing 48824-1322.; Padmanabhan K

Subjects: Protein Conformation*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemistry ; Peptide Fragments/Peptide Fragments/Peptide Fragments/*chemistry

  • Source: Biochemistry [Biochemistry] 1993 May 11; Vol. 32 (18), pp. 4727-37.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Interaction of dansylated peptidyl chloromethanes with trypsin, chymotrypsin, elastase, and thrombin.

Subjects: Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/pharmacology ; Dansyl Compounds*/Dansyl Compounds*/Dansyl Compounds*/pharmacology; Chymotrypsin/Chymotrypsin/Chymotrypsin/*metabolism

  • Source: Biochemistry [Biochemistry] 1980 Jun 24; Vol. 19 (13), pp. 2888-94.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Conformation of the active site of thiolsubtilisin: reaction with specific chloromethyl ketones and arylacryloylimidazoles.

Subjects: Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/Amino Acid Chloromethyl Ketones*/pharmacology ; Imidazoles* ; Subtilisins*/Subtilisins*/Subtilisins*/antagonists & inhibitors

  • Source: Biochemistry [Biochemistry] 1979 Aug 21; Vol. 18 (17), pp. 3764-8.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Active site selective labeling of serine proteases with spectroscopic probes using thioester peptide chloromethyl ketones: demonstration of thrombin labeling using N alpha-[(acetylthio)acetyl]-D-Phe-Pro-Arg-CH2Cl.

  • Authors : Bock PE; American Red Cross Blood Services, Southeastern Michigan Region, Detroit 48232.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*metabolism ; Serine Endopeptidases/Serine Endopeptidases/Serine Endopeptidases/*metabolism ; Thrombin/Thrombin/Thrombin/*metabolism

  • Source: Biochemistry [Biochemistry] 1988 Aug 23; Vol. 27 (17), pp. 6633-9.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Synthesis of peptides of arginine chloromethyl ketone. Selective inactivation of human plasma kallikrein.

Subjects: Protease Inhibitors*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemical synthesis ; Kallikreins/Kallikreins/Kallikreins/*antagonists & inhibitors

  • Source: Biochemistry [Biochemistry] 1978 Oct 31; Vol. 17 (22), pp. 4778-84.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Identification of an opioid receptor subunit carrying the mu binding site.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*metabolism ; Receptors, Opioid/Receptors, Opioid/Receptors, Opioid/*metabolism; Affinity Labels/Affinity Labels/Affinity Labels/metabolism

  • Source: Biochemistry [Biochemistry] 1984 Nov 06; Vol. 23 (23), pp. 5385-9.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Evidence for hemiketals as intermediates in the inactivation of serine proteinases with halomethyl ketones.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemical synthesis ; Endopeptidases/Endopeptidases/Endopeptidases/*metabolism ; Fluoroacetates/Fluoroacetates/Fluoroacetates/*chemical synthesis

  • Source: Biochemistry [Biochemistry] 1986 Apr 22; Vol. 25 (8), pp. 2298-301.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

15N and 1H NMR spectroscopy of the catalytic histidine in chloromethyl ketone-inhibited complexes of serine proteases.

  • Authors : Tsilikounas E; Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.; Rao T

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Histidine/Histidine/Histidine/*chemistry ; Serine Proteinase Inhibitors/Serine Proteinase Inhibitors/Serine Proteinase Inhibitors/*pharmacology

  • Source: Biochemistry [Biochemistry] 1996 Feb 20; Vol. 35 (7), pp. 2437-44.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.

  • Authors : Kreutter K; Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254.; Steinmetz AC

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Chymotrypsin/Chymotrypsin/Chymotrypsin/*chemistry ; Dipeptides/Dipeptides/Dipeptides/*pharmacology

  • Source: Biochemistry [Biochemistry] 1994 Nov 22; Vol. 33 (46), pp. 13792-800.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN:

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  • 1-10 of  39 results for ""Amino Acid Chloromethyl Ketones""