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Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury.

• Authors : Tallon C; Johns Hopkins Drug Discovery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Subjects: Brain Injuries/Brain Injuries/Brain Injuries/*enzymology ; Extracellular Vesicles/Extracellular Vesicles/Extracellular Vesicles/*enzymology ; Microglia/Microglia/Microglia/*enzymology

• Source: Biochemical pharmacology [Biochem Pharmacol] 2021 Dec; Vol. 194, pp. 114796. Date of Electronic Publication: 2021 Oct 20.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor.

• Authors : Jeske J; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology Stuttgart, Germany and University of Tübingen, Germany.; Bitter A

Subjects: Hepatocytes/Hepatocytes/Hepatocytes/*metabolism ; Liver X Receptors/Liver X Receptors/Liver X Receptors/*metabolism ; Receptor Cross-Talk/Receptor Cross-Talk/Receptor Cross-Talk/*physiology

• Source: Biochemical pharmacology [Biochem Pharmacol] 2017 Jul 15; Vol. 136, pp. 122-135. Date of Electronic Publication: 2017 Apr 13.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Stimulation of CD95-induced apoptosis in T-cells by a subtype specific neutral sphingomyelinase inhibitor.

• Authors : Amtmann E; German Cancer Research Center, Abteilung Immunregulation und Tumorabwehr, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. ; Zöller M

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*antagonists & inhibitors ; T-Lymphocytes/T-Lymphocytes/T-Lymphocytes/*drug effects

• Source: Biochemical pharmacology [Biochem Pharmacol] 2005 Apr 15; Vol. 69 (8), pp. 1141-8.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print Cited Medium: Print ISSN: 0006-2952 (Print)

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New oleyl glycoside as anti-cancer agent that targets on neutral sphingomyelinase.

• Authors : Romero-Ramírez L; Hospital Nacional de Parapléjicos, SESCAM, Finca la Peraleda s/n, 45071 Toledo, Spain. Electronic address: .; García-Álvarez I

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*metabolism ; Glycosides/Glycosides/Glycosides/*administration & dosage

• Source: Biochemical pharmacology [Biochem Pharmacol] 2015 Sep 15; Vol. 97 (2), pp. 158-72. Date of Electronic Publication: 2015 Jul 20.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Agricola

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Promising neuroprotective effects of β-caryophyllene against LPS-induced oligodendrocyte toxicity: A mechanistic study.

• Authors : Askari VR; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran; Student Research Committee, Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: .

Subjects: Lipopolysaccharides/Lipopolysaccharides/Lipopolysaccharides/*toxicity ; Neuroprotective Agents/Neuroprotective Agents/Neuroprotective Agents/*pharmacology ; Oligodendroglia/Oligodendroglia/Oligodendroglia/*drug effects

• Source: Biochemical pharmacology [Biochem Pharmacol] 2019 Jan; Vol. 159, pp. 154-171. Date of Electronic Publication: 2018 Dec 05.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Effects of phospholipases C on the beta-receptor-adenylate cyclase system of chick erythrocyte membranes.

• Authors : Nakajima M; Taguchi R; Ikezawa H

Subjects: Adenylyl Cyclases/Adenylyl Cyclases/Adenylyl Cyclases/*metabolism ; Erythrocyte Membrane/Erythrocyte Membrane/Erythrocyte Membrane/*enzymology ; Receptors, Adrenergic, beta/Receptors, Adrenergic, beta/Receptors, Adrenergic, beta/*metabolism

• Source: Biochemical pharmacology [Biochem Pharmacol] 1986 Sep 15; Vol. 35 (18), pp. 3031-8.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print Cited Medium: Print ISSN: 0006-2952 (Print)

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