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Academic Journal

6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model.

  • Authors : Li ZC; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, PR China.; Li M

Subjects: NFATC Transcription Factors*/NFATC Transcription Factors*/NFATC Transcription Factors*/metabolism ; Bone Resorption*/Bone Resorption*/Bone Resorption*/drug therapy ; Bone Resorption*/Bone Resorption*/Bone Resorption*/metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2024 Jun; Vol. 224, pp. 116230. Date of Electronic Publication: 2024 Apr 20.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Oroxylin A reduces osteoclast formation and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation.

  • Authors : Xian Y; Guangxi Key Laboratory of Regenerative Medicine, Research Centre for Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi, China; Guangxi Collaborative Innovation Center for Biomedicine, Guangxi Medical University, Nanning, Guangxi, China.

Subjects: Bone Resorption/Bone Resorption/Bone Resorption/*prevention & control ; Flavonoids/Flavonoids/Flavonoids/*pharmacology ; Macrophages/Macrophages/Macrophages/*drug effects

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2021 Nov; Vol. 193, pp. 114761. Date of Electronic Publication: 2021 Sep 04.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca 2+ -NFATc1 signaling pathway and prevents ovariectomy-induced bone loss.

  • Authors : Zeng X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Department of Pharmacology, Hainan Medical College, Haikou 571199, China.

Subjects: Ovariectomy*; Artemisinins/Artemisinins/Artemisinins/*pharmacology ; Calcium/Calcium/Calcium/*metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2017 Jan 15; Vol. 124, pp. 57-68. Date of Electronic Publication: 2016 Oct 24.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Trapidil, a platelet-derived growth factor antagonist, inhibits osteoclastogenesis by down-regulating NFATc1 and suppresses bone loss in mice.

  • Authors : Kim SD; Department of Cell and Developmental Biology, Dental Research Institute, School of Dentistry, Seoul National University, Seoul 110-749, Republic of Korea.; Kim HN

Subjects: Bone Density Conservation Agents/Bone Density Conservation Agents/Bone Density Conservation Agents/*pharmacology ; Bone Resorption/Bone Resorption/Bone Resorption/*prevention & control ; Bone and Bones/Bone and Bones/Bone and Bones/*drug effects

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2013 Sep 15; Vol. 86 (6), pp. 782-90. Date of Electronic Publication: 2013 Aug 06.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Aminocoumarins inhibit osteoclast differentiation and bone resorption via downregulation of nuclear factor of activated T cells c1.

  • Authors : Zheng T; College of Pharmacy, Sookmyung Women's University, Seoul 140-742, Republic of Korea.; Noh AL

Subjects: Aminocoumarins/Aminocoumarins/Aminocoumarins/*pharmacology ; Bone Resorption/Bone Resorption/Bone Resorption/*metabolism ; Cell Differentiation/Cell Differentiation/Cell Differentiation/*drug effects

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2013 Feb 01; Vol. 85 (3), pp. 417-25. Date of Electronic Publication: 2012 Nov 01.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The profile of immune modulation by cannabidiol (CBD) involves deregulation of nuclear factor of activated T cells (NFAT).

  • Authors : Kaplan BL; Center for Integrative Toxicology and Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, USA.; Springs AE

Subjects: Cannabidiol/Cannabidiol/Cannabidiol/*pharmacology ; Immunologic Factors/Immunologic Factors/Immunologic Factors/*pharmacology ; NFATC Transcription Factors/NFATC Transcription Factors/NFATC Transcription Factors/*antagonists & inhibitors

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2008 Sep 15; Vol. 76 (6), pp. 726-37. Date of Electronic Publication: 2008 Jul 08.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Regulation of the hypertonic stress response and other cellular functions by the Rel-like transcription factor NFAT5.

  • Authors : Aramburu J; Molecular Immunopathology Unit, Department of Experimental and Health Sciences (DCEXS), Universitat Pompeu Fabra, Carrer Dr. Aiguader 80, E-08003 Barcelona, Spain. ; Drews-Elger K

Subjects: Adaptation, Physiological* ; Gene Expression Regulation*; NFATC Transcription Factors/NFATC Transcription Factors/NFATC Transcription Factors/*genetics

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2006 Nov 30; Vol. 72 (11), pp. 1597-604. Date of Electronic Publication: 2006 Aug 14.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Bavachalcone inhibits osteoclast differentiation through suppression of NFATc1 induction by RANKL.

  • Authors : Park CK; Department of Cell and Developmental Biology, BK21 Program, Dental Research Institute, Seoul National University School of Dentistry, 28 Yeongon-Dong, Chongno-Gu, Seoul 110-749, Republic of Korea.; Lee Y

Subjects: Chalcones/Chalcones/Chalcones/*pharmacology ; Flavones/Flavones/Flavones/*pharmacology ; NFATC Transcription Factors/NFATC Transcription Factors/NFATC Transcription Factors/*metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2008 Jun 01; Vol. 75 (11), pp. 2175-82. Date of Electronic Publication: 2008 Mar 21.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The acetaminophen-derived bioactive N-acylphenolamine AM404 inhibits NFAT by targeting nuclear regulatory events.

  • Authors : Caballero FJ; Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Facultad de Medicina, Avda. de Menendez Pidal s/n, 14004 Córdoba, Spain.; Navarrete CM

Subjects: Arachidonic Acids/Arachidonic Acids/Arachidonic Acids/*pharmacology ; NFATC Transcription Factors/NFATC Transcription Factors/NFATC Transcription Factors/*antagonists & inhibitors; Acetaminophen/Acetaminophen/Acetaminophen/chemistry

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2007 Apr 01; Vol. 73 (7), pp. 1013-23. Date of Electronic Publication: 2006 Dec 15.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Inhibition of interleukin-4 production in activated T cells via the downregulation of AP-1/NF-AT activation by N-lauroyl-D-erythro-sphingosine and N-lauroyl-D-erythro-C20-sphingosine.

  • Authors : Park J; School of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.; Kim SH

Subjects: CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*drug effects ; Ceramides/Ceramides/Ceramides/*pharmacology ; Interleukin-4/Interleukin-4/Interleukin-4/*metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2006 Apr 14; Vol. 71 (8), pp. 1229-39. Date of Electronic Publication: 2006 Jan 31.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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  • 1-10 of  27 results for ""NFATC Transcription Factors""