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  • 1-10 of  64 results for ""Sphingomyelin Phosphodiesterase""

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Academic Journal

N-glycosylation of human sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is essential for stability, secretion and activity.

  • Authors : Traini M; Atherosclerosis Laboratory, ANZAC Research Institute, University of Sydney, NSW, Australia .; Kumaran R

Subjects: Monocytes/Monocytes/Monocytes/*enzymology ; Recombinant Fusion Proteins/Recombinant Fusion Proteins/Recombinant Fusion Proteins/*chemistry ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*chemistry

  • Source: The Biochemical journal [Biochem J] 2017 Mar 08; Vol. 474 (7), pp. 1071-1092. Date of Electronic Publication: 2017 Mar 08.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Electronic

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Academic Journal

Neutral sphingomyelinase-2 is a redox sensitive enzyme: role of catalytic cysteine residues in regulation of enzymatic activity through changes in oligomeric state.

  • Authors : Dotson PP 2nd; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY 40536, U.S.A.; Karakashian AA

Subjects: Cysteine/Cysteine/Cysteine/*physiology ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*metabolism; Animals

  • Source: The Biochemical journal [Biochem J] 2015 Feb 01; Vol. 465 (3), pp. 371-82.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells.

  • Authors : Clarke CJ; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA.; Cloessner EA

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Carcinoma/Carcinoma/Carcinoma/*pathology ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*metabolism

  • Source: The Biochemical journal [Biochem J] 2011 Apr 15; Vol. 435 (2), pp. 381-90.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

PKCzeta protects against UV-C-induced apoptosis by inhibiting acid sphingomyelinase-dependent ceramide production.

  • Authors : Charruyer A; Inserm, U563, Centre de Physiopathologie de Toulouse Purpan, Toulouse, F-31300, France.; Jean C

Subjects: Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/antagonists & inhibitors ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/metabolism; Apoptosis/Apoptosis/Apoptosis/*radiation effects

  • Source: The Biochemical journal [Biochem J] 2007 Jul 01; Vol. 405 (1), pp. 77-83.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis.

  • Authors : Wu J; Gastroenterology Lab, Biomedical Center B11, Lund University, S-221 84 Lund, Sweden.; Hansen GH

Subjects: Protein Processing, Post-Translational*/Protein Processing, Post-Translational*/Protein Processing, Post-Translational*/drug effects; Cations, Divalent/Cations, Divalent/Cations, Divalent/*metabolism ; Intestines/Intestines/Intestines/*enzymology

  • Source: The Biochemical journal [Biochem J] 2005 Feb 15; Vol. 386 (Pt 1), pp. 153-60.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

A neutral sphingomyelinase resides in sphingolipid-enriched microdomains and is inhibited by the caveolin-scaffolding domain: potential implications in tumour necrosis factor signalling.

  • Authors : Veldman RJ; INSERM 466, CHU Rangueil, 1 avenue Jean Poulhès, 31403 Toulouse, France.; Maestre N

Subjects: Caveolins/Caveolins/Caveolins/*pharmacology ; Signal Transduction/Signal Transduction/Signal Transduction/*physiology ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*metabolism

  • Source: The Biochemical journal [Biochem J] 2001 May 01; Vol. 355 (Pt 3), pp. 859-68.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Neutral sphingomyelinase activity dependent on Mg2+ and anionic phospholipids in the intraerythrocytic malaria parasite Plasmodium falciparum.

  • Authors : Hanada K; Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases, 1-23-1, Toyama, Shinjuku-ku, Tokyo 162-8640, Japan. ; Mitamura T

Subjects: Magnesium/Magnesium/Magnesium/*metabolism ; Phospholipids/Phospholipids/Phospholipids/*metabolism ; Plasmodium falciparum/Plasmodium falciparum/Plasmodium falciparum/*metabolism

  • Source: The Biochemical journal [Biochem J] 2000 Mar 15; Vol. 346 Pt 3, pp. 671-7.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Rapid replenishment of sphingomyelin in the plasma membrane upon degradation by sphingomyelinase in NIH3T3 cells overexpressing the phosphatidylinositol transfer protein beta.

  • Authors : Van Tiel CM; Institute of Biomembranes, Center for Biomembranes and Lipid Enzymology, Department Biochemistry of Lipids, Utrecht University, P. O. Box 80.054, 3508 TB Utrecht, The Netherlands.; Luberto C

Subjects: Membrane Proteins*; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Cell Membrane/Cell Membrane/Cell Membrane/*metabolism

  • Source: The Biochemical journal [Biochem J] 2000 Mar 01; Vol. 346 Pt 2, pp. 537-43.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Evidence against involvement of the acid lysosomal sphingomyelinase in the tumor-necrosis-factor- and interleukin-1-induced sphingomyelin cycle and cell proliferation in human fibroblasts.

  • Authors : Andrieu N; CJF INSERM 9206, Institut Louis Bugnard, C.H.U. Rangueil, Toulouse, France.; Salvayre R

Subjects: Fibroblasts/Fibroblasts/Fibroblasts/*drug effects ; Interleukin-1/Interleukin-1/Interleukin-1/*pharmacology ; Peptide Fragments/Peptide Fragments/Peptide Fragments/*pharmacology

  • Source: The Biochemical journal [Biochem J] 1994 Oct 15; Vol. 303 ( Pt 2), pp. 341-5.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Occurrence of two molecular forms of human acid sphingomyelinase.

  • Authors : Ferlinz K; Institut für Organische Chemie und Biochemie, Bonn, Germany.; Hurwitz R

Subjects: Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*biosynthesis; Base Sequence ; Cell Line

  • Source: The Biochemical journal [Biochem J] 1994 Aug 01; Vol. 301 ( Pt 3), pp. 855-62.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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  • 1-10 of  64 results for ""Sphingomyelin Phosphodiesterase""