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Academic Journal

Sphingomyelin phosphodiesterase 1 (SMPD1) mediates the attenuation of myocardial infarction-induced cardiac fibrosis by astaxanthin.

  • Authors : Shi Y; Department of Cardiology, Yantai Yuhuangding Hospital, Yantai, Shandong Province, 264001, China.; Lin P

Subjects: Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*therapeutic use ; Fibrinolytic Agents/Fibrinolytic Agents/Fibrinolytic Agents/*therapeutic use ; Myocardial Infarction/Myocardial Infarction/Myocardial Infarction/*drug therapy

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Sep 05; Vol. 503 (2), pp. 637-643. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2.

  • Authors : Bilousova T; Drug Discovery Lab, Department of Neurology, University of California, Los Angeles, CA, USA; Gylys Lab, School of Nursing, University of California, Los Angeles, CA, USA.

Subjects: Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Naphthalenes/Naphthalenes/Naphthalenes/*pharmacology ; Pyrimidinones/Pyrimidinones/Pyrimidinones/*pharmacology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 May 23; Vol. 499 (4), pp. 751-757. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Alpha-mangostin attenuates diabetic nephropathy in association with suppression of acid sphingomyelianse and endoplasmic reticulum stress.

  • Authors : Liu T; Department of Endocrinology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China; Department of Endocrinology, Haikou People's Hospital, Haikou, Hainan, 570208, China.

Subjects: Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*drug therapy ; Diabetic Nephropathies/Diabetic Nephropathies/Diabetic Nephropathies/*drug therapy ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Feb 05; Vol. 496 (2), pp. 394-400. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency.

  • Authors : Acuña M; Departamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Center of Genome Regulation (Fondap 15090007), Universidad de Chile, Santiago, Chile. Electronic address: .

Subjects: Niemann-Pick Diseases/Niemann-Pick Diseases/Niemann-Pick Diseases/*genetics ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*metabolism; Alanine/Alanine/Alanine/chemistry

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2016 Oct 21; Vol. 479 (3), pp. 496-501. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.

  • Authors : Mizutani N; Department of Pathophysiological Laboratory Science, Nagoya University Graduate School of Medicine, Nagoya, Japan; College of Life and Health Sciences, Chubu University, Kasugai, Japan.

Subjects: Neoplasms, Experimental/Neoplasms, Experimental/Neoplasms, Experimental/*drug therapy ; Neoplasms, Experimental/Neoplasms, Experimental/Neoplasms, Experimental/*metabolism ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2016 Feb 19; Vol. 470 (4), pp. 851-6. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Acid sphingomyelinase (aSMase) deficiency leads to abnormal microglia behavior and disturbed retinal function.

  • Authors : Dannhausen K; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany.; Karlstetter M

Subjects: Microglia/Microglia/Microglia/*enzymology ; Retina/Retina/Retina/*enzymology ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2015 Aug 21; Vol. 464 (2), pp. 434-40. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Epigallocatechin-3-O-gallate induces acid sphingomyelinase activation through activation of phospholipase C.

  • Authors : Bae J; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, 819-0395, Japan.; Kumazoe M

Subjects: Gene Expression Regulation, Neoplastic*; Catechin/Catechin/Catechin/*analogs & derivatives ; Cyclic GMP/Cyclic GMP/Cyclic GMP/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Nov 26; Vol. 520 (1), pp. 186-191. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ceramide mediates lung fibrosis in cystic fibrosis.

  • Authors : Ziobro R; Department of Molecular Biology, University Hospital, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.; Henry B

Subjects: Ceramides/Ceramides/Ceramides/*metabolism ; Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*metabolism ; Pulmonary Fibrosis/Pulmonary Fibrosis/Pulmonary Fibrosis/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2013 May 17; Vol. 434 (4), pp. 705-9. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Role of side-edge site of sphingomyelinase from Bacillus cereus.

  • Authors : Oda M; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan. ; Takahashi M

Subjects: Bacillus cereus/Bacillus cereus/Bacillus cereus/*enzymology ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Magnesium/Magnesium/Magnesium/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2012 May 25; Vol. 422 (1), pp. 128-32. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Bacillus cereus sphingomyelinase recognizes ganglioside GM3.

  • Authors : Oda M; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. ; Fujita A

Subjects: Bacillus cereus/Bacillus cereus/Bacillus cereus/*enzymology ; G(M3) Ganglioside/G(M3) Ganglioside/G(M3) Ganglioside/*chemistry ; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*chemistry

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2013 Feb 08; Vol. 431 (2), pp. 164-8. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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