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Academic Journal

Human SMOOTHENED inhibits human immunodeficiency virus type 1 infection.

  • Authors : Yoshida T; Department of Molecular Virology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. Electronic address: .; Hamano A

Subjects: Virus Internalization*; HIV Infections/HIV Infections/HIV Infections/*immunology ; HIV-1/HIV-1/HIV-1/*immunology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2017 Nov 04; Vol. 493 (1), pp. 132-138. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.

  • Authors : Lee H; College of Pharmacy, Dongguk University-Seoul, 32 Donggukro, Ilsandonggu, Goyangsi, Gyeonggido, 10326, South Korea.; Ko HW

Subjects: Cilia/Cilia/Cilia/*metabolism ; Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism ; Signal Transduction/Signal Transduction/Signal Transduction/*physiology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2016 Nov 25; Vol. 480 (4), pp. 574-579. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

HDAC8 is implicated in embryoid body formation via canonical Hedgehog signaling and regulates neuronal differentiation.

  • Authors : Morii A; Graduate School of Pharmacy, Ritsumeikan University, Kusatsu, Shiga, 525-8577, Japan.; Inazu T

Subjects: Embryoid Bodies*/Embryoid Bodies*/Embryoid Bodies*/metabolism ; Hedgehog Proteins*/Hedgehog Proteins*/Hedgehog Proteins*/metabolism; Histone Deacetylases/Histone Deacetylases/Histone Deacetylases/genetics

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Nov 12; Vol. 629, pp. 78-85. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

De novo design of dual-target JAK2, SMO inhibitors based on deep reinforcement learning, molecular docking and molecular dynamics simulations.

  • Authors : He L; College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.; Liu J

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Janus Kinase Inhibitors*; Humans

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Jan 01; Vol. 638, pp. 23-27. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

HERC4 exerts an anti-tumor role through destabilizing the oncoprotein Smo.

  • Authors : Sun X; College of Life Sciences, Shandong Agricultural University, Tai'an, Shandong, China.; Sun B

Subjects: Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*pathology ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*pathology ; Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/*physiology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Jun 11; Vol. 513 (4), pp. 1013-1018. Date of Electronic Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effects of Icaritin on the physiological activities of esophageal cancer stem cells.

  • Authors : Han S; Thoracic Surgery Department of Gansu Province People's Hospital, Lanzhou, 730000, China.; Gou Y

Subjects: Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*pharmacology ; Esophageal Neoplasms/Esophageal Neoplasms/Esophageal Neoplasms/*pathology ; Flavonoids/Flavonoids/Flavonoids/*pharmacology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Oct 12; Vol. 504 (4), pp. 792-796. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Sonic hedgehog stimulates glycolysis and proliferation of breast cancer cells: Modulation of PFKFB3 activation.

  • Authors : Ge X; Department of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.; Lyu P

Subjects: Glycolysis*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2015 Aug 28; Vol. 464 (3), pp. 862-8. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The primary cilium undergoes dynamic size modifications during adipocyte differentiation of human adipose stem cells.

  • Authors : Forcioli-Conti N; University of Nice Sophia Antipolis, UFR Sciences, Nice F-06108, France; CNRS, UMR7277, F-06108, France

Subjects: Cell Differentiation*/Cell Differentiation*/Cell Differentiation*/drug effects; Adipocytes/Adipocytes/Adipocytes/*cytology ; Adipocytes/Adipocytes/Adipocytes/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2015 Feb 27; Vol. 458 (1), pp. 117-22. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hedgehog signaling is synergistically enhanced by nutritional deprivation and ligand stimulation in human fibroblasts of Gorlin syndrome.

  • Authors : Mizuochi H; Department of Pediatrics, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, 260-8670, Chiba, Japan. Electronic address: .; Fujii K

Subjects: Basal Cell Nevus Syndrome/Basal Cell Nevus Syndrome/Basal Cell Nevus Syndrome/*metabolism ; Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism; Anilides/Anilides/Anilides/pharmacology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2015 Feb 13; Vol. 457 (3), pp. 318-23. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Metabolites in vertebrate Hedgehog signaling.

  • Authors : Roberg-Larsen H; Department of Chemistry, University of Oslo, PO Box 1033, Blindern, NO-0315 Oslo, Norway.; Strand MF

Subjects: Chemistry Techniques, Analytical/Chemistry Techniques, Analytical/Chemistry Techniques, Analytical/*methods ; Glucocorticoids/Glucocorticoids/Glucocorticoids/*metabolism ; Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2014 Apr 11; Vol. 446 (3), pp. 669-74. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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