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Combining binding pocket mutagenesis and substrate tunnel engineering to improve an (R)-selective transaminase for the efficient synthesis of (R)-3-aminobutanol.

• Authors : Liu H; State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai, 200237, China.; Gao Q

Subjects: Transaminases*/Transaminases*/Transaminases*/metabolism ; Transaminases*/Transaminases*/Transaminases*/genetics ; Transaminases*/Transaminases*/Transaminases*/chemistry

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Oct 30; Vol. 731, pp. 150383. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Reducing the vicissitudes of heterologous prochiral substrate catalysis by alcohol dehydrogenases through machine learning algorithms.

• Authors : Ghatak A; Department of Biophysics, Molecular Biology and Bioinformatics, University of Calcutta, Kolkata, India; Biomoneta Research Pvt. Ltd., C-CAMP, National Centre for Biological Sciences (NCBS), UAS GKVK, Bangalore, 560065, India.

Subjects: Alcohol Dehydrogenase*/Alcohol Dehydrogenase*/Alcohol Dehydrogenase*/chemistry ; Algorithms*; Catalysis

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jan 08; Vol. 691, pp. 149298. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Electron withdrawing group-dependent substrate inhibition of an α-ketoamide reductase from Saccharomyces cerevisiae.

• Authors : Akbary Z; Program in Biochemistry and Molecular Biology, Drew University, 36 Madison Ave, Madison, NJ, 07940, United States.; Yu H

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Oct 08; Vol. 676, pp. 97-102. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Forming coumarin C-glycosides via biocatalysis: Characterization of a C-glycosyltransferase from Angelica decursiva.

• Authors : Wang Z; Key Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, College of Horti-culture, Hainan University (HNU), Haikou, China; Key Laboratory of Tropical Agritourism in Greenhouse of Haikou, College of Horticulture, Hainan University (HNU), Haikou, China.

Subjects: Angelica*/Angelica*/Angelica*/chemistry ; Angelica*/Angelica*/Angelica*/metabolism; Biocatalysis

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jul 23; Vol. 614, pp. 85-91. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Crystal structure of the adenylation domain from an ε-poly-l-lysine synthetase provides molecular mechanism for substrate specificity.

• Authors : Okamoto T; Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Tottori, 680-8552, Japan.; Yamanaka K

Subjects: Adenosine Monophosphate/Adenosine Monophosphate/Adenosine Monophosphate/*analogs & derivatives ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Peptide Synthases/Peptide Synthases/Peptide Synthases/*metabolism Streptomyces albulus

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Mar 12; Vol. 596, pp. 43-48. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Regiospecific 7-hydroxylation of ten-carbon monoterpenes by detoxifying CYP5035S7 monooxygenase of the white-rot fungus Polyporus arcularius.

• Authors : Fessner ND; Institute of Molecular Biotechnology, NAWI Graz, Graz University of Technology, Petersgasse 14, 8010, Graz, Austria. Electronic address: .; Weber H

Subjects: Carbon/Carbon/Carbon/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism ; Fungal Proteins/Fungal Proteins/Fungal Proteins/*metabolism Polyporus arcularius

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Mar 05; Vol. 595, pp. 35-40. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Comparative kinetic analysis of ascorbate (Vitamin-C) recycling dehydroascorbate reductases from plants and humans.

• Authors : Das BK; Membrane Protein Biology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, 110067, India; Southern California Institute for Research and Education, Veterans Affairs Long Beach Health Care System, 5901 E. 7th Street Long Beach, CA, 90822, USA.

Subjects: Ascorbic Acid/Ascorbic Acid/Ascorbic Acid/*metabolism ; Oxidoreductases/Oxidoreductases/Oxidoreductases/*metabolism ; Pennisetum/Pennisetum/Pennisetum/*enzymology

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Feb 05; Vol. 591, pp. 110-117. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Enzymatic conversion of dehydrocoelenterazine to coelenterazine using FMN-bound flavin reductase of NAD(P)H:FMN oxidoreductase.

• Authors : Inouye S; Yokohama Research Center, JNC Co., 5-1 Okawa, Kanazawa-ku, Yokohama, 236-8605, Japan. Electronic address: .; Nakamura M

Subjects: Aliivibrio fischeri/Aliivibrio fischeri/Aliivibrio fischeri/*enzymology ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Imidazoles/Imidazoles/Imidazoles/*metabolism

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jan 08; Vol. 587, pp. 24-28. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Consensus mutagenesis and computational simulation provide insight into the desaturation catalytic mechanism for delta 6 fatty acid desaturase.

• Authors : Cui J; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, PR China. Electronic address: .

Subjects: Molecular Docking Simulation*; Algal Proteins/Algal Proteins/Algal Proteins/*chemistry ; Chlorophyta/Chlorophyta/Chlorophyta/*enzymology

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jan 01; Vol. 586, pp. 74-80. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Dimeric architecture of maltodextrin glucosidase (MalZ) provides insights into the substrate recognition and hydrolysis mechanism.

• Authors : Ahn WC; Department of Biological Science, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea.

Subjects: Escherichia coli/Escherichia coli/Escherichia coli/*enzymology ; Escherichia coli Proteins/Escherichia coli Proteins/Escherichia coli Proteins/*chemistry ; Glucose/Glucose/Glucose/*chemistry

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jan 01; Vol. 586, pp. 49-54. Date of Electronic Publication: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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