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Academic Journal

A-series agent A-234: initial in vitro and in vivo characterization.

  • Authors : Hrabinova M; University of Defence, Military Faculty of Medicine, Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 01, Hradec Králové, Czech Republic.; Pejchal J

Subjects: Cholinesterase Reactivators*/Cholinesterase Reactivators*/Cholinesterase Reactivators*/pharmacology ; Pralidoxime Compounds*; Taurine/Taurine/Taurine/*analogs & derivatives

  • Source: Archives of toxicology [Arch Toxicol] 2024 Apr; Vol. 98 (4), pp. 1135-1149. Date of Electronic Publication: 2024 Mar 06.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate.

  • Authors : Bernardo LB; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. .; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. .

Subjects: Oximes*/Oximes*/Oximes*/pharmacology ; Acetylcholinesterase*/Acetylcholinesterase*/Acetylcholinesterase*/metabolism ; Cholinesterase Reactivators*/Cholinesterase Reactivators*/Cholinesterase Reactivators*/pharmacology

  • Source: Archives of toxicology [Arch Toxicol] 2024 Oct; Vol. 98 (10), pp. 3397-3407. Date of Electronic Publication: 2024 Jul 14.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Functional basis for dose-dependent antagonism of rat and rabbit neuromuscular transmission by the bis-pyridinium oxime MMB4.

  • Authors : Machamer JB; Department of Neuroscience, U.S. Army Medical Research Institute of Chemical Defense, 8350 Ricketts Point Road, Gunpowder, MD, 21010, USA.; Apland JP

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*drug effects ; Muscles/Muscles/Muscles/*drug effects ; Organophosphate Poisoning/Organophosphate Poisoning/Organophosphate Poisoning/*drug therapy

  • Source: Archives of toxicology [Arch Toxicol] 2020 Nov; Vol. 94 (11), pp. 3877-3891. Date of Electronic Publication: 2020 Jul 20.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of pyridostigmine, pralidoxime and their combination on survival and cholinesterase activity in rats exposed to the organophosphate paraoxon.

  • Authors : Petroianu GA; Faculty of Medicine and Health Sciences, Department of Pharmacology and Therapeutics, United Arab Emirates University, P.O.Box 17 666, Al Ain, United Arab Emirates. ; Nurulain SM

Subjects: Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*administration & dosage ; Paraoxon/Paraoxon/Paraoxon/*toxicity

  • Source: Archives of toxicology [Arch Toxicol] 2006 Nov; Vol. 80 (11), pp. 777-84. Date of Electronic Publication: 2006 Apr 06.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Plasma concentrations of pralidoxime methylsulphate in organophosphorus poisoned patients.

  • Authors : Willems JL; Heymans Institute of Pharmacology, University of Ghent Medical School, Belgium.; Langenberg JP

Subjects: Organothiophosphorus Compounds*; Insecticides/Insecticides/Insecticides/*poisoning ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*blood

  • Source: Archives of toxicology [Arch Toxicol] 1992; Vol. 66 (4), pp. 260-6.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print Cited Medium: Print ISSN: 0340-5761 (Print)

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Academic Journal

Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain.

  • Authors : Antonijevic E; Department of Toxicology 'Akademik Danilo Soldatović', Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, Belgrade, 11221, Serbia.; Kotur-Stevuljevic J

Subjects: Brain/Brain/Brain/*drug effects ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Dichlorvos/Dichlorvos/Dichlorvos/*toxicity

  • Source: Archives of toxicology [Arch Toxicol] 2018 Feb; Vol. 92 (2), pp. 745-757. Date of Electronic Publication: 2017 Nov 02.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Oxime-type acetylcholinesterase reactivators in pregnancy: an overview.

  • Authors : Nurulain SM; Department of Pharmacology and Therapeutics, College of Medicine and Health Science, United Arab Emirates University, P.O. Box 17666, Al Ain, UAE.; Kornelia T

Subjects: Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology ; Organophosphate Poisoning/Organophosphate Poisoning/Organophosphate Poisoning/*drug therapy ; Oximes/Oximes/Oximes/*pharmacology

  • Source: Archives of toxicology [Arch Toxicol] 2014 Mar; Vol. 88 (3), pp. 575-84. Date of Electronic Publication: 2013 Nov 21.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Therapeutic effects of HS-3, HS-6, benactyzine, and atropine in soman poisoning of dogs.

Subjects: Organophosphate Poisoning*; Atropine/Atropine/Atropine/*therapeutic use ; Benactyzine/Benactyzine/Benactyzine/*therapeutic use

  • Source: Archives of toxicology [Arch Toxicol] 1976 Sep 15; Vol. 36 (1), pp. 71-81.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print Cited Medium: Print ISSN: 0340-5761 (Print)

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Academic Journal

Direct reaction of oximes with crotylsarin, cyclosarin, or VX in vitro.

  • Authors : Becker G; Institut für Pharmakologie und Toxikologie der Bundeswehr, Neuherbergstrasse 11, 80937 München, Germany.; Kawan A

Subjects: Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*chemistry ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*chemistry ; Organophosphorus Compounds/Organophosphorus Compounds/Organophosphorus Compounds/*chemistry

  • Source: Archives of toxicology [Arch Toxicol] 2007 Jun; Vol. 81 (6), pp. 415-20. Date of Electronic Publication: 2006 Dec 07.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Acetylcholinesterase inhibition: does it explain the toxicity of organophosphorus compounds?

  • Authors : Maxwell DM; US Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010-5400, USA. ; Brecht KM

Subjects: Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*toxicity ; Organophosphorus Compounds/Organophosphorus Compounds/Organophosphorus Compounds/*toxicity; Animals

  • Source: Archives of toxicology [Arch Toxicol] 2006 Nov; Vol. 80 (11), pp. 756-60. Date of Electronic Publication: 2006 Jun 13.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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