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Academic Journal

Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway.

  • Authors : Zhang T; Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, 201203, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.

Subjects: Liver Neoplasms, Experimental*/Liver Neoplasms, Experimental*/Liver Neoplasms, Experimental*/drug therapy ; Liver Neoplasms, Experimental*/Liver Neoplasms, Experimental*/Liver Neoplasms, Experimental*/metabolism ; Liver Neoplasms, Experimental*/Liver Neoplasms, Experimental*/Liver Neoplasms, Experimental*/pathology

  • Source: Archives of toxicology [Arch Toxicol] 2022 Jun; Vol. 96 (6), pp. 1829-1843. Date of Electronic Publication: 2022 Mar 10.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats.

  • Authors : Naiki-Ito A; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, 1-Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan. .; Kato H

Subjects: Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*metabolism ; Connexins/Connexins/Connexins/*metabolism ; Liver/Liver/Liver/*metabolism

  • Source: Archives of toxicology [Arch Toxicol] 2020 Dec; Vol. 94 (12), pp. 4085-4097. Date of Electronic Publication: 2020 Aug 24.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tumor promotion and inhibition by phenobarbital in livers of conditional Apc-deficient mice.

  • Authors : Braeuning A; Department of Food Safety, Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany. .; Department of Toxicology, University of Tuebingen, Wilhelmstr. 56, 72074, Tuebingen, Germany. .

Subjects: Adenomatous Polyposis Coli Protein/Adenomatous Polyposis Coli Protein/Adenomatous Polyposis Coli Protein/*deficiency ; Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/*chemically induced ; Phenobarbital/Phenobarbital/Phenobarbital/*toxicity

  • Source: Archives of toxicology [Arch Toxicol] 2016 Jun; Vol. 90 (6), pp. 1481-94. Date of Electronic Publication: 2016 Feb 02.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Superoxide deficiency attenuates promotion of hepatocarcinogenesis by cytotoxicity in NADPH oxidase knockout mice.

  • Authors : Parzefall W; Department of Medicine I, Comprehensive Cancer Center, Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090, Wien, Austria.; Freiler C

Subjects: Cocarcinogenesis*; Liver/Liver/Liver/*drug effects ; Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/*chemically induced

  • Source: Archives of toxicology [Arch Toxicol] 2015 Aug; Vol. 89 (8), pp. 1383-93. Date of Electronic Publication: 2014 Sep 03.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures.

  • Authors : Phillips TD; College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, 77843, USA.; Richardson M

Subjects: DNA Repair*; DNA Adducts/DNA Adducts/DNA Adducts/*metabolism ; Liver/Liver/Liver/*drug effects

  • Source: Archives of toxicology [Arch Toxicol] 2015 Jun; Vol. 89 (6), pp. 967-77. Date of Electronic Publication: 2014 Jun 03.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice.

  • Authors : Wang X; Department of Metabolic Regulation, Shinshu University School of Medicine, Matsumoto, 390-8621, Japan.; Department of Gastroenterology, Lishui Hospital, Zhejiang University School of Medicine, Lishui, Zhejiang, People's Republic of China.

Subjects: Cholesterol, Dietary/Cholesterol, Dietary/Cholesterol, Dietary/*toxicity ; Genes, Viral/Genes, Viral/Genes, Viral/*genetics ; Hepatitis C/Hepatitis C/Hepatitis C/*genetics

  • Source: Archives of toxicology [Arch Toxicol] 2019 Jun; Vol. 93 (6), pp. 1713-1725. Date of Electronic Publication: 2019 Apr 19.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophen.

  • Authors : Singh Y; Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, University of Tuebingen, Wilhelmstr. 56, 72074, Tübingen, Germany.; Braeuning A

Subjects: Mutation*; Acetaminophen/Acetaminophen/Acetaminophen/*pharmacology ; Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/*drug therapy

  • Source: Archives of toxicology [Arch Toxicol] 2013 Aug; Vol. 87 (8), pp. 1595-607. Date of Electronic Publication: 2013 Mar 12.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanistic study on liver tumor promoting effects of flutamide in rats.

  • Authors : Tawfeeq MM; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo 183-8509, Japan.; Hayashi H

Subjects: Androgen Antagonists/Androgen Antagonists/Androgen Antagonists/*toxicity ; Flutamide/Flutamide/Flutamide/*toxicity ; Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/*chemically induced

  • Source: Archives of toxicology [Arch Toxicol] 2012 Mar; Vol. 86 (3), pp. 497-507. Date of Electronic Publication: 2011 Nov 11.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats.

  • Authors : Morita R; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo, Japan.; Shimamoto K

Subjects: Anticarcinogenic Agents/Anticarcinogenic Agents/Anticarcinogenic Agents/*pharmacology ; Liver/Liver/Liver/*drug effects ; Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/*chemically induced

  • Source: Archives of toxicology [Arch Toxicol] 2011 Nov; Vol. 85 (11), pp. 1475-84. Date of Electronic Publication: 2011 Mar 29.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.

  • Authors : Shimamoto K; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.; Dewa Y

Subjects: Cytochrome P-450 CYP1A1/Cytochrome P-450 CYP1A1/Cytochrome P-450 CYP1A1/*biosynthesis ; Flutamide/Flutamide/Flutamide/*toxicity ; Indoles/Indoles/Indoles/*toxicity

  • Source: Archives of toxicology [Arch Toxicol] 2011 Sep; Vol. 85 (9), pp. 1159-66. Date of Electronic Publication: 2011 Jan 04.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  55 results for ""Liver Neoplasms, Experimental""