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Academic Journal

The dual phosphodiesterase 3/4 inhibitor RPL554 stimulates rare class III and IV CFTR mutants.

  • Authors : Turner MJ; Department of Physiology, McGill University, Montreal, Quebec, Canada.; Cystic Fibrosis Translational Research Centre, McGill University, Montreal, Quebec, Canada.

Subjects: Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism ; Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/*genetics ; Isoquinolines/Isoquinolines/Isoquinolines/*pharmacology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 May 01; Vol. 318 (5), pp. L908-L920. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.

  • Authors : Nino G; Joseph Stokes Jr. Research Institute, Division of Pulmonary Medicine, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.; Hu A

Subjects: Desensitization, Immunologic*; Asthma/Asthma/Asthma/*metabolism ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*immunology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2009 Oct; Vol. 297 (4), pp. L746-57. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1.

  • Authors : Murray F; Department of Pharmacology, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0636, USA.; Patel HH

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*genetics ; 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*metabolism ; Hypertension, Pulmonary/Hypertension, Pulmonary/Hypertension, Pulmonary/*enzymology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2007 Jan; Vol. 292 (1), pp. L294-303. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure.

  • Authors : Tarpey SB; Department of Physiology, University of South Alabama, Mobile, Alabama 36688, USA.; Sawmiller DR

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*metabolism ; Heart Failure/Heart Failure/Heart Failure/*metabolism ; Lung/Lung/Lung/*enzymology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2003 May; Vol. 284 (5), pp. L766-73. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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