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Shedding of klotho by ADAMs in the kidney.

• Authors : van Loon, Ellen P. M.; Pulskens, Wilco P.; van der Hagen, Eline A. E.

Subjects: FIBROBLAST growth factor receptors; HOMEOSTASIS; KIDNEY physiology

• Source: American Journal of Physiology: Renal Physiology; 8/15/2015, Vol. 309 Issue 4, pF359-F368, 10p

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Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice.

• Authors : Salem, Esam S. B.; Grobe, Nadja; Elased, Khalid M.

Subjects: INSULIN therapy; ANGIOTENSIN converting enzyme; VASOCONSTRICTORS

• Source: American Journal of Physiology: Renal Physiology; Mar2014, Vol. 306 Issue 6, pF629-F639, 11p

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Role of ADAM17 in kidney disease.

• Authors : Palau, Vanesa; Pascual, Julio; José Soler, Maria

• Source: American Journal of Physiology: Renal Physiology; Aug2019, Vol. 317 Issue 2, pF333-F342, 10p, 5 Diagrams

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ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice.

• Authors : Ford, Bridget M.; Eid, Assaad A.; Göoz, Monika

Subjects: DIABETIC nephropathies; EXTRACELLULAR matrix proteins; KIDNEY tubules

• Source: American Journal of Physiology: Renal Physiology; Aug2013, Vol. 305 Issue 2, pF323-F332, 10p

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ADAM17 upregulation in human renal disease: a role in modulating TGF-α availability?

• Authors : Melenhorst, W. B.; Visser, L.; Timmer, A.

Subjects: METALLOPROTEINASES; EPIDERMAL growth factor; TUMOR necrosis factors

• Source: American Journal of Physiology: Renal Physiology; Sep2009, Vol. 297, pF781-F790, 10p, 4 Charts, 10 Graphs

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H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells.

• Authors : Shougang Zhougang; Schnellmann, Rick G.

Subjects: EPIDERMAL growth factor; HYDROGEN peroxide; EPITHELIAL cells

• Source: American Journal of Physiology: Renal Physiology; May2004, Vol. 286, pF858-F865, 8p, 20 Black and White Photographs, 3 Graphs

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Hypertonic induction of COX-2 expression in renal medullary epithelial cells requires transactivation of the EGFR.

• Authors : Hongyu Zhao; Wei Tian; Tai, Cynthia

Subjects: CYCLOOXYGENASE 2; GENE expression; CELLULAR signal transduction

• Source: American Journal of Physiology: Renal Physiology; Aug2003, Vol. 54 Issue 2, pF281, 8p, 7 Diagrams, 2 Graphs

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