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Academic Journal

Assessing the Mechanism of Rac1b: An All-Atom Simulation Study of the Alternative Spliced Variant of Rac1 Small Rho GTPase.

  • Authors : Cresca S; Theory Department, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia.; Consiglio Nazionale delle Ricerche (CNR)-IOM, c/o International School for Advanced Studies (SISSA/ISAS), via Bonomea 265, 34136 Trieste, Italy.

Subjects: rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/metabolism ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/chemistry ; Molecular Dynamics Simulation*

  • Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 Dec 23; Vol. 64 (24), pp. 9474-9486. Date of Electronic Publication: 2024 Dec 05.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

pERK transition-induced directional mode switching promotes epithelial tumor cell migration.

  • Authors : Yu H; Shenzhen Key Laboratory of Metabolism and Cardiovascular Homeostasis, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518055, China.; School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518060, China.

Subjects: Cell Movement* ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/metabolism ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Dec 17; Vol. 121 (51), pp. e2318871121. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovarian cancer.

  • Authors : Tocci P; Preclinical Models and New Therapeutic Agents Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Regina Elena National Cancer Institute, Rome, Italy.; Caprara V

Subjects: Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/pathology ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/genetics

  • Source: Bioscience reports [Biosci Rep] 2024 Dec 17; Vol. 44 (12).Publisher: Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 8102797 Publication Model: Print Cited Medium:

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Academic Journal

Repurposing an epithelial sodium channel inhibitor as a therapy for murine and human skin inflammation.

  • Authors : Winge MCG; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Nasrallah M

Subjects: Keratinocytes*/Keratinocytes*/Keratinocytes*/metabolism ; Keratinocytes*/Keratinocytes*/Keratinocytes*/drug effects ; Amiloride*/Amiloride*/Amiloride*/analogs & derivatives

  • Source: Science translational medicine [Sci Transl Med] 2024 Dec 11; Vol. 16 (777), pp. eade5915. Date of Electronic Publication: 2024 Dec 11.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic

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Academic Journal

Spatial and planar profiling of Rac1/Cdc42 signaling in Alzheimer's disease brain.

  • Authors : Akhtar SN; Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.; Department of Chemistry and Biochemistry, The University of South Carolina, Columbia, SC, USA.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

  • Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2024 Dec; Vol. 102 (3), pp. 670-682. Date of Electronic Publication: 2024 Nov 29.Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Circulating RAC1 contributed to steroid-sensitive nephrotic syndrome: Mendelian randomization, single-cell RNA-sequencing, proteomic, and experimental evidence.

  • Authors : Zhang Y; Department of Nephrology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Yao T

Subjects: rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/metabolism ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/genetics ; Mendelian Randomization Analysis*

  • Source: Renal failure [Ren Fail] 2024 Dec; Vol. 46 (2), pp. 2416087. Date of Electronic Publication: 2024 Oct 18.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

WDR12/RAC1 axis promoted proliferation and anti-apoptosis in colorectal cancer cells.

  • Authors : Wen S; Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road No.1095, Wuhan, 430030, Hubei, China.; Huang X

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/metabolism ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics

  • Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2024 Dec; Vol. 479 (12), pp. 3341-3354. Date of Electronic Publication: 2024 Feb 11.Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Additional statin treatment enhances the efficacy of HER2 blockade and improves prognosis in Rac1-high/HER2-positive breast cancer.

  • Authors : Kato C; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Iizuka-Ohashi M

Subjects: rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/metabolism ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/genetics ; Receptor, ErbB-2*/Receptor, ErbB-2*/Receptor, ErbB-2*/metabolism

  • Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Dec; Vol. 1870 (8), pp. 167458. Date of Electronic Publication: 2024 Aug 10.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

[Research progress in the small G-protein Rac1].

  • Authors : Yang Y; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225100, Jiangsu, China.; Zhao S

Subjects: rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/metabolism ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/genetics ; Virus Replication*

  • Source: Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2024 Nov 25; Vol. 40 (11), pp. 3902-3911.Publisher: Ke xue chu ban she Country of Publication: China NLM ID: 9426463 Publication Model: Print Cited Medium: Internet ISSN: 1872-2075

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Academic Journal

TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis.

  • Authors : Ren W; School of Life Science, University of Science & Technology of China, Hefei, Anhui, China.; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.

Subjects: Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/genetics ; Neovascularization, Pathologic*/Neovascularization, Pathologic*/Neovascularization, Pathologic*/genetics

  • Source: Cell death & disease [Cell Death Dis] 2024 Nov 13; Vol. 15 (11), pp. 821. Date of Electronic Publication: 2024 Nov 13.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  5,462 results for ""rac1 GTP-Binding Protein""