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  • 10-20 of  1,233 results for ""Liver-Specific Organic Anion Transporter 1""

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Academic Journal

Hepatic OATP1B zonal distribution: Implications for rifampicin-mediated drug-drug interactions explored within a PBPK framework.

  • Authors : Hartauer M; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Murphy WA

Subjects: Rifampin*/Rifampin*/Rifampin*/pharmacokinetics ; Rifampin*/Rifampin*/Rifampin*/pharmacology ; Drug Interactions*

  • Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Sep; Vol. 13 (9), pp. 1513-1527. Date of Electronic Publication: 2024 Jun 19.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

SLCO1B1 and ABCG2 genotype-informed phenotypes are related to variation in ramipril exposure.

  • Authors : Abbes H; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria La Princesa (IP), Madrid, Spain.; Biochemistry Department, LR12SP11, Sahloul University Hospital, Sousse, Tunisia.

Subjects: ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/metabolism ; Ramipril*/Ramipril*/Ramipril*/pharmacokinetics

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2024 Sep; Vol. 135 (3), pp. 295-307. Date of Electronic Publication: 2024 Jul 16.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

The reduced function allele SLCO1B1 c.521T>C is of no practical relevance for the renal graft function over the first post-transplant year in patients treated with mycophenolic acid.

Subjects: Kidney Transplantation*/Kidney Transplantation*/Kidney Transplantation*/adverse effects ; Mycophenolic Acid*/Mycophenolic Acid*/Mycophenolic Acid*/adverse effects ; Mycophenolic Acid*/Mycophenolic Acid*/Mycophenolic Acid*/administration & dosage

  • Source: Pharmacogenetics and genomics [Pharmacogenet Genomics] 2024 Sep 01; Vol. 34 (7), pp. 226-235. Date of Electronic Publication: 2024 May 20.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101231005 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Mechanistic Account of Distinct Change in Organic Anion Transporting Polypeptide 1B (OATP1B) Substrate Pharmacokinetics during OATP1B-Mediated Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling.

  • Authors : Hegde PV; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.; Morse BL

Subjects: Drug Interactions*/Drug Interactions*/Drug Interactions*/physiology ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/metabolism ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/genetics

  • Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2024 Jul 16; Vol. 52 (8), pp. 886-898. Date of Electronic Publication: 2024 Jul 16.Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model:

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Academic Journal

Effect of Strong CYP3A4 Inhibition, CYP3A4 Induction, and OATP1B1/3 Inhibition on the Pharmacokinetics of a Single Oral Dose of Sotorasib.

  • Authors : Cardona P; Clinical Pharmacology, Modeling and Simulation, Amgen Inc., Thousand Oaks, CA, USA.; Dutta S

Subjects: Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/antagonists & inhibitors ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/antagonists & inhibitors

  • Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2024 Jul; Vol. 13 (7), pp. 810-818. Date of Electronic Publication: 2024 Feb 29.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Clinical Practice Perspective on the Evaluation of OATP1B1-associated Drug Interactions.

  • Authors : Stäuble CK; Biopharmacy, Pharmaceutical Sciences, University of Basel, Basel, Switzerland.; Pharmaceutical Care, Pharmaceutical Sciences, University of Basel, Basel, Switzerland.

Subjects: Drug Interactions* ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/metabolism ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/genetics

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Jul; Vol. 116 (1), pp. 30-33. Date of Electronic Publication: 2024 Mar 14.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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Academic Journal

Mechanistic Determinants of Daprodustat Drug-Drug Interactions and Pharmacokinetics in Hepatic Dysfunction and Chronic Kidney Disease: Significance of OATP1B-CYP2C8 Interplay.

  • Authors : Bi YA; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA.; Jordan S

Subjects: Cytochrome P-450 CYP2C8*/Cytochrome P-450 CYP2C8*/Cytochrome P-450 CYP2C8*/metabolism ; Drug Interactions* ; Hepatocytes*/Hepatocytes*/Hepatocytes*/metabolism

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Jun; Vol. 115 (6), pp. 1336-1345. Date of Electronic Publication: 2024 Feb 26.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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Academic Journal

Physiologically Based Pharmacokinetic Model of OATP1B Substrates with a Nonlinear Mixed Effect Approach: Estimating Empirical In Vitro-to-In Vivo Scaling Factors.

  • Authors : Li R; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Cambridge, MA, 02139, USA. .; Kimoto E

Subjects: Models, Biological* ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/metabolism ; Nonlinear Dynamics*

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Aug; Vol. 63 (8), pp. 1177-1189. Date of Electronic Publication: 2024 Aug 19.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Allelic frequencies of polymorphism c.521T>C (rs4149056) favor preemptive SLCO1B1 genotyping in Armenia.

Subjects: Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/genetics ; Gene Frequency* ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2024 Jul 15; Vol. 39 (3), pp. 159-161. Date of Electronic Publication: 2024 Jul 15 (Print Publication: 2024).Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: eCollection Cited Medium: Internet ISSN: 2363-8915

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Academic Journal

Interactions of oleanane pentacyclic triterpenoids with human organic anion transporting polypeptide 1B1 and 1B3.

  • Authors : Tian Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.; Wang X

Subjects: Oleanolic Acid*/Oleanolic Acid*/Oleanolic Acid*/analogs & derivatives ; Oleanolic Acid*/Oleanolic Acid*/Oleanolic Acid*/pharmacology ; Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism

  • Source: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2024 Jun; Vol. 98, pp. 105842. Date of Electronic Publication: 2024 May 16.Publisher: Pergamon Press Country of Publication: England NLM ID: 8712158 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 10-20 of  1,233 results for ""Liver-Specific Organic Anion Transporter 1""