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Academic Journal

A distinct role of STING in regulating glucose homeostasis through insulin sensitivity and insulin secretion.

  • Authors : Qiao J; Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin 300052, China.; Zhang Z

Subjects: Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*metabolism ; Glucose/Glucose/Glucose/*metabolism ; Glucose Intolerance/Glucose Intolerance/Glucose Intolerance/*chemically induced

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Feb 15; Vol. 119 (7).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited

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Editorial & Opinion

High brain lactate is not caused by a shift in the lactate dehydrogenase A/B ratio.

Subjects: Aging/Aging/Aging/*metabolism ; Biomarkers/Biomarkers/Biomarkers/*metabolism ; Brain/Brain/Brain/*enzymology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 Feb 15; Vol. 108 (7), pp. E21; author reply Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.

  • Authors : Klebig ML; Biology Division, Oak Ridge National Laboratory, TN 37831-8080, USA.; Wilkinson JE

Subjects: Intercellular Signaling Peptides and Proteins* ; Protein Biosynthesis*; Aging/Aging/Aging/*physiology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1995 May 23; Vol. 92 (11), pp. 4728-32.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited

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Academic Journal

Senolytic and senomorphic agent procyanidin C1 alleviates structural and functional decline in the aged retina.

  • Authors : Liu Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510060, People's Republic of China.; Liu X

Subjects: Retina*/Retina*/Retina*/metabolism ; Retina*/Retina*/Retina*/drug effects ; Proanthocyanidins*/Proanthocyanidins*/Proanthocyanidins*/pharmacology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 30; Vol. 121 (18), pp. e2311028121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction.

  • Authors : Woo JR; Division of Convergence Technology, New Drug Development Center, KBIOHealth, Cheongju 28160, Republic of Korea.; Bae SH

Subjects: Insulin Resistance* ; Diabetes Mellitus, Type 2*; Mice

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 23; Vol. 121 (17), pp. e2401716121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair.

  • Authors : Shao S; Calibr, a Division of Scripps Research, La Jolla, CA 92037.; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.

Subjects: Alveolar Epithelial Cells*/Alveolar Epithelial Cells*/Alveolar Epithelial Cells*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism; Animals

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 16; Vol. 121 (16), pp. e2400077121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Intracellular C3 protects β-cells from IL-1β-driven cytotoxicity via interaction with Fyn-related kinase.

  • Authors : Kulak K; Section of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö 214-28, Sweden.; Kuska K

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/metabolism ; Islets of Langerhans*/Islets of Langerhans*/Islets of Langerhans*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Feb 20; Vol. 121 (8), pp. e2312621121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Neuronal MML-1/MXL-2 regulates systemic aging via glutamate transporter and cell nonautonomous autophagic and peroxidase activity.

  • Authors : Shioda T; Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University, Osaka 565-0871, Japan.; Takahashi I

Subjects: Aging*/Aging*/Aging*/genetics ; Neurons*; Animals

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Sep 26; Vol. 120 (39), pp. e2221553120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.

  • Authors : Adam RC; Regeneron Pharmaceuticals, Tarrytown, NY 10591.; Pryce DS

Subjects: Lipolysis* ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism; Humans

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug 08; Vol. 120 (32), pp. e2309967120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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Academic Journal

NFIA in adipocytes reciprocally regulates mitochondrial and inflammatory gene program to improve glucose homeostasis.

  • Authors : Hiraike Y; Division for Health Service Promotion, The University of Tokyo, Tokyo 113-0033, Japan.; The University of Tokyo Excellent Young Researcher Program, The University of Tokyo, Tokyo 113-8654, Japan.

Subjects: NFI Transcription Factors* ; Diabetes Mellitus, Type 2*; Humans

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug; Vol. 120 (31), pp. e2308750120. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model:

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