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Academic Journal

Modelling the Interplay between Lifestyle Factors and Genetic Predisposition on Markers of Type 2 Diabetes Mellitus Risk.

  • Authors : Walker CG; MRC Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, United Kingdom.; Solis-Trapala I

Subjects: Genetic Predisposition to Disease* ; Life Style* ; Models, Biological*

  • Source: PloS one [PLoS One] 2015 Jul 08; Vol. 10 (7), pp. e0131681. Date of Electronic Publication: 2015 Jul 08 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.

  • Authors : Kumar A; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America; Biotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Bethesda, Maryland, United States of America.

Subjects: Algorithms* ; Disease Models, Animal* ; Models, Biological*

  • Source: PloS one [PLoS One] 2014 Jul 16; Vol. 9 (7), pp. e102319. Date of Electronic Publication: 2014 Jul 16 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues.

  • Authors : Zake DM; Latvian Biomedical Research and Study Centre, Riga, Latvia.; Institute of Microbiology and Biotechnology, University of Latvia, Riga, Latvia.

Subjects: Models, Biological*; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*drug therapy ; Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*pharmacokinetics

  • Source: PloS one [PLoS One] 2021 Apr 07; Vol. 16 (4), pp. e0249594. Date of Electronic Publication: 2021 Apr 07 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Devil in the details: Mechanistic variations impact information transfer across models of transcriptional cascades.

  • Authors : Rowland MA; Environmental Laboratory, U.S. Army Engineer Research and Development Center, Vicksburg, MS, United States of America.; Pilkiewicz KR

Subjects: Gene Expression Regulation* ; Gene Regulatory Networks* ; Models, Biological*

  • Source: PloS one [PLoS One] 2021 Jan 13; Vol. 16 (1), pp. e0245094. Date of Electronic Publication: 2021 Jan 13 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A statistical model to identify determinants of glycemic control in patients with type 2 diabetes with different pharmacotherapeutic profiles.

  • Authors : Moura AM; Department of Social Pharmacy, Faculty of Pharmacy, University of Lisbon, Lisboa, Portugal.; Antunes M

Subjects: Models, Biological*; Blood Glucose/Blood Glucose/Blood Glucose/*analysis ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*drug therapy

  • Source: PloS one [PLoS One] 2020 Jul 06; Vol. 15 (7), pp. e0235376. Date of Electronic Publication: 2020 Jul 06 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes.

  • Authors : Jeon S; Department of Marketing Information Consulting, Mokwon University, Daejeon, KOREA.; Shin JY

Subjects: Genetic Association Studies* ; Genetic Predisposition to Disease* ; Models, Biological*

  • Source: PloS one [PLoS One] 2019 Sep 12; Vol. 14 (9), pp. e0217189. Date of Electronic Publication: 2019 Sep 12 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A robust data-driven genomic signature for idiopathic pulmonary fibrosis with applications for translational model selection.

  • Authors : Ammar R; Translational Bioinformatics, Translational Medicine, Bristol-Myers Squibb, Princeton, NJ, United States of America.; Sivakumar P

Subjects: Gene Expression Profiling* ; Gene Expression Regulation* ; Models, Biological*

  • Source: PloS one [PLoS One] 2019 Apr 18; Vol. 14 (4), pp. e0215565. Date of Electronic Publication: 2019 Apr 18 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A closed-loop multi-level model of glucose homeostasis.

  • Authors : Uluseker C; The Microsoft Research - University of Trento Centre for Computational and Systems Biology (COSBI), Rovereto (TN), Italy.; Simoni G

Subjects: Homeostasis* ; Models, Biological*; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*metabolism

  • Source: PloS one [PLoS One] 2018 Feb 08; Vol. 13 (2), pp. e0190627. Date of Electronic Publication: 2018 Feb 08 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Bi-stability in type 2 diabetes mellitus multi-organ signalling network.

  • Authors : Kulkarni S; Biology, Indian Institute of Science Education and Research, Pashan, Pune, Maharashtra, India.; Sharda S

Subjects: Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*metabolism ; Glucose Intolerance/Glucose Intolerance/Glucose Intolerance/*metabolism ; Insulin/Insulin/Insulin/*blood

  • Source: PloS one [PLoS One] 2017 Aug 02; Vol. 12 (8), pp. e0181536. Date of Electronic Publication: 2017 Aug 02 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Self-Organizing Global Gene Expression Regulated through Criticality: Mechanism of the Cell-Fate Change.

  • Authors : Tsuchiya M; Systems Biology Program, School of Media and Governance, Keio University, Fujisawa, Japan.; Giuliani A

Subjects: Models, Biological*; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*physiology ; Genome, Human/Genome, Human/Genome, Human/*physiology

  • Source: PloS one [PLoS One] 2016 Dec 20; Vol. 11 (12), pp. e0167912. Date of Electronic Publication: 2016 Dec 20 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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