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Academic Journal

Unraveling the impact of AXIN1 mutations on HCC development: Insights from CRISPR/Cas9 repaired AXIN1-mutant liver cancer cell lines.

  • Authors : Zhang R; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands.; Yunnan Key Laboratory of Chiral Functional Substance Research and Application, School of Chemistry & Environment, Yunnan Minzu University, Kunming, China.

Subjects: Axin Protein*/Axin Protein*/Axin Protein*/genetics ; Axin Protein*/Axin Protein*/Axin Protein*/metabolism ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics

  • Source: PloS one [PLoS One] 2024 Jun 07; Vol. 19 (6), pp. e0304607. Date of Electronic Publication: 2024 Jun 07 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Insufficient radiofrequency ablation promotes angiogenesis of residual hepatocellular carcinoma via HIF-1α/VEGFA.

  • Authors : Kong J; Department of Hepatobiliary Surgery, West Campus, Capital Medical University, Beijing Chao-yang Hospital, Beijing, People's Republic of China.; Kong J

Subjects: Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*pathology ; Catheter Ablation/Catheter Ablation/Catheter Ablation/*adverse effects ; Hyperthermia, Induced/Hyperthermia, Induced/Hyperthermia, Induced/*adverse effects

  • Source: PloS one [PLoS One] 2012; Vol. 7 (5), pp. e37266. Date of Electronic Publication: 2012 May 15.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Down-regulation of hepatic expression of GHR/STAT5/IGF-1 signaling pathway fosters development and aggressiveness of HCV-related hepatocellular carcinoma: Crosstalk with Snail-1 and type 2 transforming growth factor-beta receptor.

  • Authors : Abu El-Makarem MA; Department of Internal Medicine, School of Medicine, Minia University, Minia, Egypt.; Kamel MF

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Liver Neoplasms* ; Hepatitis C*

  • Source: PloS one [PLoS One] 2022 Nov 14; Vol. 17 (11), pp. e0277266. Date of Electronic Publication: 2022 Nov 14 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Nrf2 signaling promotes cancer stemness, migration, and expression of ABC transporter genes in sorafenib-resistant hepatocellular carcinoma cells.

  • Authors : Gao L; Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.; Morine Y

Subjects: Gene Expression* ; Gene Expression Regulation, Neoplastic*; ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/*genetics

  • Source: PloS one [PLoS One] 2021 Sep 02; Vol. 16 (9), pp. e0256755. Date of Electronic Publication: 2021 Sep 02 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Role of long intergenic non-protein coding RNA 01857 in hepatocellular carcinoma malignancy via the regulation of the microRNA-197-3p/anterior GRadient 2 axis.

  • Authors : Bi J; Department of Hepatopancreatobiliary Surgery, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.; Guo Y

Subjects: Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*genetics ; MicroRNAs/MicroRNAs/MicroRNAs/*genetics

  • Source: PloS one [PLoS One] 2021 Nov 18; Vol. 16 (11), pp. e0258312. Date of Electronic Publication: 2021 Nov 18 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting the PI3K/AKT/mTOR pathways and DNA damage repair.

  • Authors : Xie Y; Huainan First People's Hospital and First Affiliated Hospital of Medical School, Anhui University of Science and Technology, Huainan, China.; Liu C

Subjects: Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*therapy ; Chemoradiotherapy/Chemoradiotherapy/Chemoradiotherapy/*methods ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*therapy

  • Source: PloS one [PLoS One] 2021 Oct 19; Vol. 16 (10), pp. e0258817. Date of Electronic Publication: 2021 Oct 19 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

PGE2 upregulates the Na+/K+ ATPase in HepG2 cells via EP4 receptors and intracellular calcium.

  • Authors : Hodeify R; Department of Biotechnology, School of Arts and Sciences, American University of Ras Al Khaimah, Ras Al Khaimah, United Arab Emirates.; Chakkour M

Subjects: Calcium/Calcium/Calcium/*metabolism ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*pathology ; Dinoprostone/Dinoprostone/Dinoprostone/*pharmacology

  • Source: PloS one [PLoS One] 2021 Jan 14; Vol. 16 (1), pp. e0245400. Date of Electronic Publication: 2021 Jan 14 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer.

  • Authors : Chandrashekar DS; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, United States of America.; Golonka RM

Subjects: Gene Expression Regulation, Neoplastic*; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*pathology ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*pathology

  • Source: PloS one [PLoS One] 2020 Jun 19; Vol. 15 (6), pp. e0234726. Date of Electronic Publication: 2020 Jun 19 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

HNF-4α inhibits hepatocellular carcinoma cell proliferation through mir-122-adam17 pathway.

  • Authors : Yang G; Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, China.; Zhang M

Subjects: ADAM17 Protein/ADAM17 Protein/ADAM17 Protein/*genetics ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics ; Hepatocyte Nuclear Factor 4/Hepatocyte Nuclear Factor 4/Hepatocyte Nuclear Factor 4/*genetics

  • Source: PloS one [PLoS One] 2020 Mar 25; Vol. 15 (3), pp. e0230450. Date of Electronic Publication: 2020 Mar 25 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells.

  • Authors : Chao X; The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, P. R.China.; The College of Basic Medicine Sciences, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi, P. R.China.

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*metabolism ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects

  • Source: PloS one [PLoS One] 2019 Jan 07; Vol. 14 (1), pp. e0201864. Date of Electronic Publication: 2019 Jan 07 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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