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Academic Journal

Tailored Melatonin- and Donepezil-Based Hybrids Targeting Pathognomonic Changes in Alzheimer's Disease: An In Vitro and In Vivo Investigation.

  • Authors : Mihaylova R; Department 'Pharmacology, Pharmacotherapy and Toxicology', Faculty of Pharmacy, Medical University of Sofia, 1431 Sofia, Bulgaria.; Angelova VT

Subjects: Donepezil*/Donepezil*/Donepezil*/pharmacology ; Donepezil*/Donepezil*/Donepezil*/therapeutic use ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 29; Vol. 25 (11). Date of Electronic Publication: 2024 May 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer's Disease.

  • Authors : Vicente-Zurdo D; Department of Analytical Chemistry, Faculty of Chemistry Sciences, Complutense University of Madrid, 28040 Madrid, Spain.; Centre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Faculty of Pharmacy, Universidad San Pablo-CEU, CEU Universities, Montepríncipe Urbanization, 28660 Boadilla del Monte, Spain.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Polyphenols*/Polyphenols*/Polyphenols*/therapeutic use

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 28; Vol. 25 (11). Date of Electronic Publication: 2024 May 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Geniposide and Harpagoside Functionalized Cerium Oxide Nanoparticles as a Potential Neuroprotective.

  • Authors : Pérez Gutiérrez RM; Natural Products Research Laboratory, Higher School of Chemical Engineering and Extractive Industries, National Polytechnic Institute (IPN), Av. National Polytechnic Institute S/N, Mexico City 07708, Mexico.; Rodríguez-Serrano LM

Subjects: Cerium*/Cerium*/Cerium*/chemistry ; Cerium*/Cerium*/Cerium*/pharmacology ; Iridoids*/Iridoids*/Iridoids*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 11; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease.

  • Authors : Kiss E; Institute of Anatomy and Cell Biology, University of Heidelberg, 69120 Heidelberg, Germany.; Department of Cellular and Molecular Biology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mures, 540142 Târgu Mures, Romania.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Artemisinins*/Artemisinins*/Artemisinins*/therapeutic use

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 09; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Neuroprotection and Mechanism of Gas-miR36-5p from Gastrodia elata in an Alzheimer's Disease Model by Regulating Glycogen Synthase Kinase-3β.

  • Authors : Lu Z; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.; Fu J

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 09; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Glutathione-Mediated Neuroprotective Effect of Purine Derivatives.

  • Authors : Matsumura N; Department of Pharmacology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi, Tokyo 173-8605, Japan.; Aoyama K

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/prevention & control ; Glutathione*/Glutathione*/Glutathione*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 22; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

N-Acetylcysteine Amide against Aβ-Induced Alzheimer's-like Pathology in Rats.

  • Authors : Alkandari AF; Department of Anatomy, College of Medicine, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.; Madhyastha S

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/chemically induced ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Neuroprotective Agents*/Neuroprotective Agents*/Neuroprotective Agents*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 12; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

An RNAi-Mediated Reduction in Transcription Factor Nrf-2 Blocks the Positive Effects of Dimethyl Fumarate on Metabolic Stress in Alzheimer's Disease.

  • Authors : Lanza M; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.; Basilotta R

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Dimethyl Fumarate*/Dimethyl Fumarate*/Dimethyl Fumarate*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 11; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease.

  • Authors : Parrado Fernandez C; AlzeCure Pharma AB, Hälsovägen 7, 141 57 Huddinge, Sweden.; Division of Neuroscience, Care and Society, Department of Neurogeriatrics, Karolinska Institutet, 171 77 Solna, Sweden.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Neuroblastoma*/Neuroblastoma*/Neuroblastoma*/drug therapy ; Neuroprotective Agents*/Neuroprotective Agents*/Neuroprotective Agents*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 06; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Multi-Targeting Neuroprotective Effects of Syzygium aromaticum Bud Extracts and Their Key Phytocompounds against Neurodegenerative Diseases.

  • Authors : Sharma H; Department of Bionano Technology, Gachon Bionano Research Institute, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si 461-701, Gyeonggi-do, Republic of Korea.; Kim DY

Subjects: Neuroprotective Agents*/Neuroprotective Agents*/Neuroprotective Agents*/pharmacology ; Syzygium*/Syzygium*/Syzygium*/metabolism ; Neurodegenerative Diseases*/Neurodegenerative Diseases*/Neurodegenerative Diseases*/drug therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 May 02; Vol. 24 (9). Date of Electronic Publication: 2023 May 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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