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Academic Journal

ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming.

Subjects: PROSTATE; GENE silencing; PROSTATE cancer

  • Source: Journal of Clinical Investigation. Nov2020, Vol. 130 Issue 11, p5924-5941. 18p. 7 Color Photographs, 3 Diagrams.

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Academic Journal

Differential impact of RB status on E2F1 reprogramming in human cancer.

Subjects: RETINOBLASTOMA; TRANSCRIPTION factors; PROSTATE cancer patients

  • Source: Journal of Clinical Investigation. Jan2018, Vol. 128 Issue 1, p341-358. 18p. 1 Color Photograph, 7 Graphs.

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Academic Journal

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.

Subjects: NEUROBLASTOMA; TRANSCRIPTION factors; CANCER treatment

  • Source: Journal of Clinical Investigation. Jan2018, Vol. 128 Issue 1, p446-462. 17p. 1 Diagram, 9 Graphs.

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Academic Journal

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis.

Subjects: FIBROSIS; DISEASES; MORTALITY

  • Source: Journal of Clinical Investigation. Aug2016, Vol. 126 Issue 8, p3063-3079. 15p. 7 Color Photographs, 2 Graphs.

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Academic Journal

Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development.

Subjects: TRANSCRIPTION factors; TRETINOIN; SPLEEN diseases

  • Source: Journal of Clinical Investigation. Jul2016, Vol. 126 Issue 7, p2452-2464. 13p. 3 Diagrams, 6 Graphs.

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Academic Journal

Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs.

Subjects: TRANSCRIPTION factors; T cells; CELLULAR signal transduction

  • Source: Journal of Clinical Investigation. 3/1/2016, Vol. 126 Issue 3, p865-878. 14p. 1 Diagram, 3 Charts, 7 Graphs.

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